NSG5003 WEEK 2 QUIZ EXAM
QUESTIONS WITH 100% CORRECT
ANSWERS LATEST VERSION 2025/2026.
c.
Altered immunologic response to an antigen that results in disease - ANS Hypersensitivity is
best defined as a(an)
Anaphylaxis - ANS A hypersensitivity reaction that produces an allergic response is called:
IgE - ANS The common hay fever allergy is expressed through a reaction that is mediated by
which class of immunoglobulins?
IgE - ANS Which type of antibody is involved in type I hypersensitivity reaction?
Alloimmunity - ANS Blood transfusion reactions are an example of:
c.
Eosinophils - ANS During an IgE-mediated hypersensitivity reaction, which leukocyte is
activated?
1 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,Histamine bound to H2 - ANS During an IgE-mediated hypersensitivity reaction, the
degranulation of mast cells is a result of which receptor action?
c.
Greater quantities of IgE - ANS What characteristic do atopic individuals have that make them
genetically predisposed to develop allergies?
d.
Antibodies bind to the antigens on the cell surface. - ANS What is the mechanism that results
in type II hypersensitivity reactions?
a.
Complement-mediated cell lysis - ANS When mismatched blood is administered causing an
ABO incompatibility, the erythrocytes are destroyed by
Phagocytosis in the spleen - ANS When antibodies are formed against red blood cell antigens
of the Rh system, the blood cells are destroyed by:
d.
Neutrophil granules and toxic oxygen products - ANS When soluble antigens from infectious
agents enter circulation, tissue damage is a result of:
d.
Natural killer cells - ANS How are target cells destroyed in a type II hypersensitivity reaction?
Modulation - ANS Graves disease (hyperthyroidism) is an example of which type II
hypersensitivity reaction?
2 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,b.
Antibodies binding to soluble antigens that were released into body fluids and the immune
complexes being deposited in the tissues - ANS Type III hypersensitivity reactions are a result
of which of the following?
.
Lymphokine-producing Th1 cells directly attacking and destroying cellular targets - ANS A
type IV hypersensitivity reaction causes which result?
Complement activation - ANS In a type III hypersensitivity reaction, the harmful effects after
the immune complexes that are deposited in tissues are a result of:
a.
Immune complexes that are deposited in capillary beds, blocking circulation - ANS Raynaud
phenomenon is classified as a type III hypersensitivity reaction and is due to:
Zinc - ANS Deficiencies in which element can produce depression of both B- and T-cell
function?
Alloimmunity - ANS When the maternal immune system becomes sensitized against antigens
expressed by the fetus, what reaction occurs?
Systemic lupus erythematosus - ANS Tissue damage caused by the deposition of circulating
immune complexes containing an antibody against the host DNA is the cause of which disease?
a.
Th1 cells release cytokines that activate infiltrating macrophages, and cytotoxic T cells directly
attack the endothelial cells of the transplanted tissue. - ANS Why does tissue damage occurs
in acute rejection after organ transplantation?
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, Erythrocytes - ANS Which blood cell carries the carbohydrate antigens for blood type?
A and B - ANS A person with type O blood is likely to have high titers of which anti-
antibodies?
IgM - ANS Which class of immunoglobulins forms isohemagglutinins?
T cells - ANS Which component of the immune system is deficient in individuals with
infections caused by viruses, fungi, or yeast?
DiGeorge syndrome - ANS In which primary immune deficiency is there a partial-to-complete
absence of T-cell immunity?
6 to 8 - ANS How many months does it take for the newborn to be sufficiently protected by
antibodies produced by its own B cells?
T cells - ANS Considering the effects of nutritional deficiencies on the immune system, severe
deficits in calories and protein lead to deficiencies in the formation of which immune cells?
Type I - ANS Urticaria are a manifestation of a which type of hypersensitivity reaction?
c.
Autoantibodies binding to thyroid-stimulating hormone (TSH)-receptor sites - ANS Graves
disease is a result of:
Type III - ANS Raynaud phenomenon is an example of which type of hypersensitivity?
4 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
QUESTIONS WITH 100% CORRECT
ANSWERS LATEST VERSION 2025/2026.
c.
Altered immunologic response to an antigen that results in disease - ANS Hypersensitivity is
best defined as a(an)
Anaphylaxis - ANS A hypersensitivity reaction that produces an allergic response is called:
IgE - ANS The common hay fever allergy is expressed through a reaction that is mediated by
which class of immunoglobulins?
IgE - ANS Which type of antibody is involved in type I hypersensitivity reaction?
Alloimmunity - ANS Blood transfusion reactions are an example of:
c.
Eosinophils - ANS During an IgE-mediated hypersensitivity reaction, which leukocyte is
activated?
1 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,Histamine bound to H2 - ANS During an IgE-mediated hypersensitivity reaction, the
degranulation of mast cells is a result of which receptor action?
c.
Greater quantities of IgE - ANS What characteristic do atopic individuals have that make them
genetically predisposed to develop allergies?
d.
Antibodies bind to the antigens on the cell surface. - ANS What is the mechanism that results
in type II hypersensitivity reactions?
a.
Complement-mediated cell lysis - ANS When mismatched blood is administered causing an
ABO incompatibility, the erythrocytes are destroyed by
Phagocytosis in the spleen - ANS When antibodies are formed against red blood cell antigens
of the Rh system, the blood cells are destroyed by:
d.
Neutrophil granules and toxic oxygen products - ANS When soluble antigens from infectious
agents enter circulation, tissue damage is a result of:
d.
Natural killer cells - ANS How are target cells destroyed in a type II hypersensitivity reaction?
Modulation - ANS Graves disease (hyperthyroidism) is an example of which type II
hypersensitivity reaction?
2 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
,b.
Antibodies binding to soluble antigens that were released into body fluids and the immune
complexes being deposited in the tissues - ANS Type III hypersensitivity reactions are a result
of which of the following?
.
Lymphokine-producing Th1 cells directly attacking and destroying cellular targets - ANS A
type IV hypersensitivity reaction causes which result?
Complement activation - ANS In a type III hypersensitivity reaction, the harmful effects after
the immune complexes that are deposited in tissues are a result of:
a.
Immune complexes that are deposited in capillary beds, blocking circulation - ANS Raynaud
phenomenon is classified as a type III hypersensitivity reaction and is due to:
Zinc - ANS Deficiencies in which element can produce depression of both B- and T-cell
function?
Alloimmunity - ANS When the maternal immune system becomes sensitized against antigens
expressed by the fetus, what reaction occurs?
Systemic lupus erythematosus - ANS Tissue damage caused by the deposition of circulating
immune complexes containing an antibody against the host DNA is the cause of which disease?
a.
Th1 cells release cytokines that activate infiltrating macrophages, and cytotoxic T cells directly
attack the endothelial cells of the transplanted tissue. - ANS Why does tissue damage occurs
in acute rejection after organ transplantation?
3 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
, Erythrocytes - ANS Which blood cell carries the carbohydrate antigens for blood type?
A and B - ANS A person with type O blood is likely to have high titers of which anti-
antibodies?
IgM - ANS Which class of immunoglobulins forms isohemagglutinins?
T cells - ANS Which component of the immune system is deficient in individuals with
infections caused by viruses, fungi, or yeast?
DiGeorge syndrome - ANS In which primary immune deficiency is there a partial-to-complete
absence of T-cell immunity?
6 to 8 - ANS How many months does it take for the newborn to be sufficiently protected by
antibodies produced by its own B cells?
T cells - ANS Considering the effects of nutritional deficiencies on the immune system, severe
deficits in calories and protein lead to deficiencies in the formation of which immune cells?
Type I - ANS Urticaria are a manifestation of a which type of hypersensitivity reaction?
c.
Autoantibodies binding to thyroid-stimulating hormone (TSH)-receptor sites - ANS Graves
disease is a result of:
Type III - ANS Raynaud phenomenon is an example of which type of hypersensitivity?
4 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
