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T or F. Beyond use date must be applied to each compounded product using USP 795
guidelines for Nonaqueous Liquids and Solid formulation and for Water-containing
Formulations. - Correct Answer-True
T or F. Beyond use date must be applied to each compounded product using USP 795
guidelines for Nonaqueous Liquids and Solid formulation and for Water-containing
Formulations. - Correct Answer-True
Which of the following is considered with Non-Sterile Preparation? A. USP 795 B. USP
797 - Correct Answer-A
Which of the following is considered with Non-Sterile Preparation? A. USP 795 B. USP
797 - Correct Answer-A
Labels on Pharmacy-compounded products - Expiration Dates (Beyond Use Dates) -
Correct Answer-* Water containing oral formulations *
> The beyond use date is no later than 14 days when stored at controlled cold
temperature
* Water containing topical/dermal/mucosal rliquid rand rsemisolid rformulations r*
> rThe rbeyond ruse rdate ris rno rlater rthan r30 rdays r
* rNonaqueous rformulations*
> rThe rbeyond ruse rdate ris rno rlater rthan rthe rtime rremaining runtil rthe rearliest
rexpiration rdate rof rany rAPI r(use rno rlater rthan r25% rof rtime rof rthis rapi) ror r6 rmonths,
rwhichever ris rearlier
Labels ron rPharmacy-compounded rproducts r- rExpiration rDates r(Beyond rUse rDates) r-
rCorrect rAnswer-* rWater rcontaining roral rformulations r*
> rThe rbeyond ruse rdate ris rno rlater rthan r14 rdays rwhen rstored rat rcontrolled rcold
rtemperature r
* rWater rcontaining rtopical/dermal/mucosal rliquid rand rsemisolid rformulations r*
> rThe rbeyond ruse rdate ris rno rlater rthan r30 rdays r
* rNonaqueous rformulations*
> rThe rbeyond ruse rdate ris rno rlater rthan rthe rtime rremaining runtil rthe rearliest
rexpiration rdate rof rany rAPI r(use rno rlater rthan r25% rof rtime rof rthis rapi) ror r6 rmonths,
rwhichever ris rearlier
T ror rF. rFor rcapsules, rthe rlabel rmust rinclude rmcg ror rmg/capsule? r- rCorrect rAnswer-
True r- rDoes rnot rrequire rfor rtablet
,T ror rF. rFor rcapsules, rthe rlabel rmust rinclude rmcg ror rmg/capsule? r- rCorrect rAnswer-
True r- rDoes rnot rrequire rfor rtablet
T ror rF. rYou rcan rrinse rcompounding requipment rwith rtap rwater? r- rCorrect rAnswer-
False r- ryou rcan ronly rrinse rPurified rwater rfor rrinsing requipment
T ror rF. rYou rcan rrinse rcompounding requipment rwith rtap rwater? r- rCorrect rAnswer-
False r- ryou rcan ronly rrinse rPurified rwater rfor rrinsing requipment
What ris rthe rbest rcertified rsterile rcompounding renvironment rfor rinjectable rproduct?
rWhich rISO? r- rCorrect rAnswer-ISO rclass r5 r(class r100) rlaminar rair rflow rhood rwithin
rISO rclass r7 r(class r10,000) rclean rroom r* rwith rpositive rair rpressure r* rdifferential
rrelative rto radjacent rareas. r
ISO rclass r5 r(class r100) rclean rroom rwith rpositive rair rpressure rdifferential rrelative rto
radjacent rareas ror ra rbarrier risolator rthat rprovides ra rISO rclass r5 r(class r100)
renvironment rfor rcompounding
What ris rthe rbest rcertified rsterile rcompounding renvironment rfor rinjectable rproduct?
rWhich rISO? r- rCorrect rAnswer-ISO rclass r5 r(class r100) rlaminar rair rflow rhood rwithin
rISO rclass r7 r(class r10,000) rclean rroom r* rwith rpositive rair rpressure r* rdifferential
rrelative rto radjacent rareas. r
ISO rclass r5 r(class r100) rclean rroom rwith rpositive rair rpressure rdifferential rrelative rto
radjacent rareas ror ra rbarrier risolator rthat rprovides ra rISO rclass r5 r(class r100)
renvironment rfor rcompounding
T ror rF. rLiquids rin ra rcontainer rcurve rup, rtherefore rmeasure rat rthe rtop rof rthe
rmeniscus. r- rCorrect rAnswer-False. rMust rmeasure rat rthe rbottom rof rmeniscus
T ror rF. rLiquids rin ra rcontainer rcurve rup, rtherefore rmeasure rat rthe rtop rof rthe
rmeniscus. r- rCorrect rAnswer-False. rMust rmeasure rat rthe rbottom rof rmeniscus
What ris rthe rdifference rbetween rglass rand rWedge-wood/Porcelain(ceramic) rMortar
rand rPestle? r- rCorrect rAnswer-wedge-wood ror rporcelain ris rused rcommonly rand ris
rbest rfor rreducing rparticle rsize rof rdry rpowders rand rcrystals r
Glass ris rused rfor rliquids ror rchemical rthat rare roily ror rthat rwill rstain rto rthe rporcelain
What ris rthe rdifference rbetween rglass rand rWedge-wood/Porcelain(ceramic) rMortar
rand rPestle? r- rCorrect rAnswer-wedge-wood ror rporcelain ris rused rcommonly rand ris
rbest rfor rreducing rparticle rsize rof rdry rpowders rand rcrystals r
Glass ris rused rfor rliquids ror rchemical rthat rare roily ror rthat rwill rstain rto rthe rporcelain
T ror rF. rIt ris rsafe rnot rto ruse rointment rpaper rto rprepare rcreams rand rlotions rbecause
rthese rtwo rformulation rhave rthe rhighest rcontent rof rwater. rWater rcontent rwill rcause
rthe rpaper rto rmoisten, rand rpossibly rtear. r- rCorrect rAnswer-True. rwe rcan ruse
rGlassine rweighing rpaper
,T ror rF. rIt ris rsafe rnot rto ruse rointment rpaper rto rprepare rcreams rand rlotions rbecause
rthese rtwo rformulation rhave rthe rhighest rcontent rof rwater. rWater rcontent rwill rcause
rthe rpaper rto rmoisten, rand rpossibly rtear. r- rCorrect rAnswer-True. rwe rcan ruse
rGlassine rweighing rpaper
Which rof rthe rfollowing rlevigating ragents rare rthe rbest rto rprepare raqueous rsystems
r(O/W rdispersions)? r
A. rGlycerin rB. rMineral roil rC. rCastor roil rD. rCottonseed roil rE. rTween r80 r- rCorrect
rAnswer-A. rGlycerin
r> rRest rare rgood rlevigating ragents rused rto rprepare roleaginous rsystems r(W/O) r
> rAdditional ragents rused ras rlevigating ragents rto rprepare raqueous rsystems rconsist
rof rPropylene rglycol, rpolyethylene rglycol r80
Which rof rthe rfollowing rlevigating ragents rare rthe rbest rto rprepare raqueous rsystems
r(O/W rdispersions)? r
A. rGlycerin rB. rMineral roil rC. rCastor roil rD. rCottonseed roil rE. rTween r80 r- rCorrect
rAnswer-A. rGlycerin
r> rRest rare rgood rlevigating ragents rused rto rprepare roleaginous rsystems r(W/O) r
> rAdditional ragents rused ras rlevigating ragents rto rprepare raqueous rsystems rconsist
rof rPropylene rglycol, rpolyethylene rglycol r80
Sometimes rheat ris rused rto rmix rthings reasier, rbut rit rlead rto rover-heating rwhich
rproduce rundesired rchemical-reactions. rWhat ris rthe rbest rway rto rprevent rover-
heating? r- rCorrect rAnswer-A rwater rbath rwill rhelp rprevent rover-heating
Sometimes rheat ris rused rto rmix rthings reasier, rbut rit rlead rto rover-heating rwhich
rproduce rundesired rchemical-reactions. rWhat ris rthe rbest rway rto rprevent rover-
heating? r- rCorrect rAnswer-A rwater rbath rwill rhelp rprevent rover-heating
Fill rin rthe rblank
........................ rrefer rto ra rcompound rprepared rwithout ra rspecific rformula r(not rfrom ran
rofficial rcompendium) rand rmade rspecifically rto rfill rthe rneeds rof ran rindividual rpatient r-
rCorrect rAnswer-Extemporaneous
Fill rin rthe rblank
........................ rrefer rto ra rcompound rprepared rwithout ra rspecific rformula r(not rfrom ran
rofficial rcompendium) rand rmade rspecifically rto rfill rthe rneeds rof ran rindividual rpatient r-
rCorrect rAnswer-Extemporaneous
Fill rin rthe rblank
...................... ra rsingle ragent rthat ris rused rto rsoften rand rsmooth rthe rskin. rA
rmoisturizer ris rsometimes rreferred rto ras r................, rbut rthe rterm r............ ris rused rfor
rsingle ragent, rand rmoisturizers roften rhave rcoloring, rscents, rand rother ringredients
radded r- rCorrect rAnswer-Emollients
, Fill rin rthe rblank
...................... ra rsingle ragent rthat ris rused rto rsoften rand rsmooth rthe rskin. rA
rmoisturizer ris rsometimes rreferred rto ras r................, rbut rthe rterm r............ ris rused rfor
rsingle ragent, rand rmoisturizers roften rhave rcoloring, rscents, rand rother ringredients
radded r- rCorrect rAnswer-Emollients
Fill rin rthe rblank
Oil rin rwater r, ror rwater rin rOil ris rexample rof r....... r- rCorrect rAnswer-Emulsions
Fill rin rthe rblank
Oil rin rwater r, ror rwater rin rOil ris rexample rof r....... r- rCorrect rAnswer-Emulsions
Fill rin rthe rblank
............ rIs rused rto rstabilize rthe remulsion. r........... rare rusually rsurfactants r(wetting
ragents) rthat rreduce rthe rsurface rtension rbetween rthe rtwo rliquids rso rthat rthe rtwo
rdifferent rsubstances rcan rmove rclose rto reach rother rbut rthey rwill rnot rbe rmixed
rtogether r- rCorrect rAnswer-Emulsifiers
Fill rin rthe rblank
............ rIs rused rto rstabilize rthe remulsion. r........... rare rusually rsurfactants r(wetting
ragents) rthat rreduce rthe rsurface rtension rbetween rthe rtwo rliquids rso rthat rthe rtwo
rdifferent rsubstances rcan rmove rclose rto reach rother rbut rthey rwill rnot rbe rmixed
rtogether r- rCorrect rAnswer-Emulsifiers
What ris rthe rdifference rbetween rContinental ror rdry rgum rmethod rand rEnglish, ror rwet
rgum rmethod? r- rCorrect rAnswer-Both rhave rsame ringredients r(oil, rpurified rwater rand
rgum r(such ras racacia) rin rthe rratio rof r4:2:1 rbut rthe rorder rof rmixing ris rdifferent.
Dry rmethod: rgum ris rmixed rrapidly rwith roil rthen rwater radded rall rat ronce
Wet rmethod: rgum ris rdissolved rin rwater rfirst, rthen roil ris rslowly radded
What ris rthe rdifference rbetween rContinental ror rdry rgum rmethod rand rEnglish, ror rwet
rgum rmethod? r- rCorrect rAnswer-Both rhave rsame ringredients r(oil, rpurified rwater rand
rgum r(such ras racacia) rin rthe rratio rof r4:2:1 rbut rthe rorder rof rmixing ris rdifferent.
Dry rmethod: rgum ris rmixed rrapidly rwith roil rthen rwater radded rall rat ronce
Wet rmethod: rgum ris rdissolved rin rwater rfirst, rthen roil ris rslowly radded
What ryou rknow rabout rHLB r(hydrophilic-Lipophilic rbalance) rnumber? r- rCorrect
rAnswer-#s rrange rfrom r0-20 rwith r10 rbeing rthe rmid-point rmeans rit ris rthe rbreak rpoint
rbetween rwater rand roil rsolubility. r#>10 rmeans rhydrophilic r(water-soluble) rand r#<10
rmeans rlipophilic r(lipid-soluble)
What ryou rknow rabout rHLB r(hydrophilic-Lipophilic rbalance) rnumber? r- rCorrect
rAnswer-#s rrange rfrom r0-20 rwith r10 rbeing rthe rmid-point rmeans rit ris rthe rbreak rpoint
rbetween rwater rand roil rsolubility. r#>10 rmeans rhydrophilic r(water-soluble) rand r#<10
rmeans rlipophilic r(lipid-soluble)