ConCeptS & ConneCtionS 10th edition Complete
Study guide & exam prep bundle | updated
2024–2025 biology review, Key ConCeptS,
Chapter SummarieS, diagramS, genetiCS,
evolution, Cellular proCeSSeS, eCology & high-
yield College biology noteS
McCance & Huether’s Pathophysiology Exam
Actual Real Exam Questions and Answers | Practice Exam Test Bank and Study
Guide | Professional Certification Review
Overview
This exam is designed to evaluate your understanding of pathophysiology concepts as
presented in McCance & Huether’s textbook. It aims to prepare learners for certification
assessments by reinforcing key principles, clinical applications, and the rationale
behind pathophysiological processes.
Key Features
• Actual exam-style questions from recent testing cycles
• Well-elaborated solutions with clinical/academic reasoning
• Comprehensive practice test bank with varied difficulty levels
• Updated guidelines, protocols, and concepts
• Scenario-based applications with real-world contexts
Exam Components
• Actual Exam Questions Bank: 170 Questions
• Comprehensive Practice Exam: 30 Questions
• Study Guide Section: Concept review + explanations
Core Content Areas
1. Cell Injury and Death (20 questions)
2. Inflammation and Healing (20 questions)
, 3. Fluid and Electrolyte Imbalances (20 questions)
4. Genetics and Disease (20 questions)
5. Endocrine Disorders (20 questions)
6. Neurologic Disorders (20 questions)
7. Respiratory Disorders (20 questions)
8. Cardiovascular Disorders (20 questions)
9. Gastrointestinal Disorders (20 questions)
10. Immune Responses (20 questions)
Answer Format
Verified correct answers are provided in bold green with step-by-step rationales,
evidence-based explanations, intervention pathways, and concept clarifications.
exam QueStionS and anSwerS
Question 1
What is the primary cause of cellular injury?
A. Hypoxia
B. Genetic mutation
C. Infection
D. Inflammation
CORRECT ANSWER: A. Hypoxia
Rationale: Hypoxia is the most common insult leading to cellular injury as it deprives
cells of oxygen needed for ATP production, leading to altered cellular metabolism and
potential cell death.
Question 2
Which mechanism is responsible for the swelling of cells in response to injury?
A. Increased sodium influx
B. Decreased potassium efflux
,C. Both A and B
D. None of the above
CORRECT ANSWER: C. Both A and B
Rationale: Cell swelling occurs when there is an increase in sodium influx and a
concurrent decrease in potassium efflux, disrupting the osmotic balance and leading to
water accumulation within the cell.
Question 3
In which phase of wound healing does granulation tissue formation primarily
occur?
A. Hemostasis
B. Inflammatory phase
C. Proliferative phase
D. Remodeling phase
CORRECT ANSWER: C. Proliferative phase
Rationale: The proliferative phase is characterized by the formation of granulation
tissue, which is essential for wound healing as it provides a scaffold for new tissue
formation.
Question 4
The most common type of shock in acute inflammatory responses is:
A. Cardiogenic shock
B. Hypovolemic shock
C. Septic shock
D. Neurogenic shock
CORRECT ANSWER: C. Septic shock
Rationale: Septic shock, resulting from severe infections leading to systemic
inflammatory response syndrome (SIRS), is the most common type of shock observed
during acute inflammatory responses.
Question 5
Autoimmune diseases often result from:
A. Environmental factors only
B. Genetic predisposition only
, C. A combination of genetic and environmental factors
D. None of the above
CORRECT ANSWER: C. A combination of genetic and environmental factors
Rationale: Autoimmune diseases typically arise from a complex interplay of genetic
susceptibility and environmental triggers, which activate the immune system against
the body's own tissues.
Question 6
Which of the following is a common characteristic of chronic inflammation?
A. Neutrophil dominance
B. Angiogenesis
C. Fever
D. Edema
CORRECT ANSWER: B. Angiogenesis
Rationale: Chronic inflammation is characterized by the presence of lymphocytes and
macrophages, along with angiogenesis, the formation of new blood vessels, which
helps in delivering nutrients to the inflamed area.
Question 7
What is the primary role of the sodium-potassium pump in maintaining cellular
integrity?
A. Producing energy
B. Regulating pH
C. Maintaining osmotic balance
D. Facilitating nutrient uptake
CORRECT ANSWER: C. Maintaining osmotic balance
Rationale: The sodium-potassium pump maintains osmotic balance by moving sodium
out and potassium into the cell, crucial for cellular homeostasis and preventing cellular
swelling.
Question 8
In the context of cellular stress, what is apoptosis?
A. Severe cell injury leading to necrosis
B. Programmed cell death
C. An increase in cell size
D. A reversible cell injury