1|Page
NR565 Advanced Pharmacology Midterm Actual Exam
Preparation Newest 2025/2026 Complete 380
Questions And Correct Detailed Answers With
Rationales (Verified Answers) |Newest Version!!!
During what trimester is a pregnant woman most at risk for
adverse drug reactions with potential long term
consequences? - Answer-1st trimester (fetus most at risk
d/t rapid growth)
What is BEERS criteria? - Answer-Recommendations of
medications inappropriate for elderly (65 and older),
prescriber ultimately decides
What is the CYP450 (cytochrome P450) - Answer-liver
enzyme system where medications are metabolized, can
either be inducers or inhibitors and create drug-drug
interactions
CYP450 inducers - Answer-Speed up metabolism of drugs
(drug is cleared faster), drug has lesser effect (decrease
blood levels of drug), elevate CYP450 enzymes
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CYP450 inducers pneumonic - Answer-"Bullshit Crap GPS
INDUCES rage"
CYP450 inducer drug names - Answer-Barbituates, St
John wort, Carbamazepine, rifampin, alcohol, phenytoin,
griseofulvin, phenobarbital, sulfonylureas
CYP450 inhibitors - Answer-inhibit metabolism, increase
blood levels of medications
CYP450 pneumonic - Answer-"VISA credit card debt
INHIBITS spending on designers like CK to look GQ"
CYP450 inhibitors drug names - Answer-Valproate,
isoniazid, sulfonamides, amiodarone, chloramphenicol,
ketoconazole, grapefruit juice, quinidine
Physiological changes during pregnancy that impact
pharmacodynamics and pharmacokinetic properties of
drugs? - Answer-increase glomerular filtration rate leads to
increase durg excretion
increase hepatic metabolism
decrease tone and motility of bowel
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increase drug absorption
Examples of medications that can be teratogenic -
Answer-Antiepileptic drugs, antimicrobials such as
tetracyclines and fluoroquinolones, vitamin A in large
doses, some anticoagulants, and hormonal medications
such as diethylstilbestrol (DES).
How is absorption of intramuscular medications different in
neonates? - Answer-slow and erratic due to low blood flow
in muscles first few days of life
Why is absorption of medication in the stomach increased
in infancy? - Answer-delayed gastric emptying
Some medications that should be avoided in the pediatric
patient? - Answer-glucocorticoids, discoloration of
developing teeth with tetracyclines, and kernicterus with
sulfonamides, levofloxacin (antibiotics)
aspirin (Severe intoxication from acute overdose)
what should be included in medication administration
patient education? - Answer-dosage size and timing
, 4|Page
route and technique of administration
duration of treatment
drug storage
nature and time course of desired responses
nature and time course of adverse responses
finish taking antibiotic
What are some things that put the elderly patient at higher
risk for adverse drug reactions? - Answer-reduced renal
function
polypharmacy (the use of five or more medications daily)
greater severity of illness
presence of comorbidities
use of drugs that have a low therapeutic index (e.g.,
digoxin)
increased individual variation secondary to altered
pharmacokinetics
inadequate supervision of long-term therapy
poor patient adherence
NR565 Advanced Pharmacology Midterm Actual Exam
Preparation Newest 2025/2026 Complete 380
Questions And Correct Detailed Answers With
Rationales (Verified Answers) |Newest Version!!!
During what trimester is a pregnant woman most at risk for
adverse drug reactions with potential long term
consequences? - Answer-1st trimester (fetus most at risk
d/t rapid growth)
What is BEERS criteria? - Answer-Recommendations of
medications inappropriate for elderly (65 and older),
prescriber ultimately decides
What is the CYP450 (cytochrome P450) - Answer-liver
enzyme system where medications are metabolized, can
either be inducers or inhibitors and create drug-drug
interactions
CYP450 inducers - Answer-Speed up metabolism of drugs
(drug is cleared faster), drug has lesser effect (decrease
blood levels of drug), elevate CYP450 enzymes
,2|Page
CYP450 inducers pneumonic - Answer-"Bullshit Crap GPS
INDUCES rage"
CYP450 inducer drug names - Answer-Barbituates, St
John wort, Carbamazepine, rifampin, alcohol, phenytoin,
griseofulvin, phenobarbital, sulfonylureas
CYP450 inhibitors - Answer-inhibit metabolism, increase
blood levels of medications
CYP450 pneumonic - Answer-"VISA credit card debt
INHIBITS spending on designers like CK to look GQ"
CYP450 inhibitors drug names - Answer-Valproate,
isoniazid, sulfonamides, amiodarone, chloramphenicol,
ketoconazole, grapefruit juice, quinidine
Physiological changes during pregnancy that impact
pharmacodynamics and pharmacokinetic properties of
drugs? - Answer-increase glomerular filtration rate leads to
increase durg excretion
increase hepatic metabolism
decrease tone and motility of bowel
,3|Page
increase drug absorption
Examples of medications that can be teratogenic -
Answer-Antiepileptic drugs, antimicrobials such as
tetracyclines and fluoroquinolones, vitamin A in large
doses, some anticoagulants, and hormonal medications
such as diethylstilbestrol (DES).
How is absorption of intramuscular medications different in
neonates? - Answer-slow and erratic due to low blood flow
in muscles first few days of life
Why is absorption of medication in the stomach increased
in infancy? - Answer-delayed gastric emptying
Some medications that should be avoided in the pediatric
patient? - Answer-glucocorticoids, discoloration of
developing teeth with tetracyclines, and kernicterus with
sulfonamides, levofloxacin (antibiotics)
aspirin (Severe intoxication from acute overdose)
what should be included in medication administration
patient education? - Answer-dosage size and timing
, 4|Page
route and technique of administration
duration of treatment
drug storage
nature and time course of desired responses
nature and time course of adverse responses
finish taking antibiotic
What are some things that put the elderly patient at higher
risk for adverse drug reactions? - Answer-reduced renal
function
polypharmacy (the use of five or more medications daily)
greater severity of illness
presence of comorbidities
use of drugs that have a low therapeutic index (e.g.,
digoxin)
increased individual variation secondary to altered
pharmacokinetics
inadequate supervision of long-term therapy
poor patient adherence
