TESTBANK
PATHOPHYSIOLOGY
THEBIOLOGICBASISFORDISEASEINADULTSANDCHILDREN
6V 6V 6V 6V 6V 6V 6V 6V
8thEdition
6v
KathrynL.McCance,SueE.Huether
6v 6v 6v 6v
, 2
y, 6vy,6vy,
Contents
Chapter01:CellularBiology ............................................................................................................................4
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6 6v
Chapter02:Altered Cellular andTissueBiology:Environmental Agents ...........................................................18
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6 6v 6v
Chapter03:TheCellularEnvironment: Fluids andElectrolytes, Acids andBases ................................................31
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6 6v 6v 6v 6v 6v 6v 6v
Chapter04:GenesandGeneticDiseases ........................................................................................................44
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6 6v 6v v
6
Chapter05:Genes, Environment-Lifestyle,and Common Diseases .................................................................55
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6 6v 6v
Chapter06:Epigenetics and Disease..............................................................................................................63
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6 6v 6v
Chapter07:InnateImmunity:InflammationandWoundHealing.....................................................................68
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6 6v 6v 6v v
6 6v
Chapter08:Adaptive Immunity ....................................................................................................................83
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6 6v
Chapter09:Alterationsin Immunity andInflammation...................................................................................95
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6 6v 6v 6v
Chapter10:Infection .................................................................................................................................108
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6
Chapter11:StressandDisease ....................................................................................................................117
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6
Chapter12:CancerBiology .........................................................................................................................124
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6
Chapter13:CancerEpidemiology ...............................................................................................................137
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6
Chapter14:Cancerin Children ....................................................................................................................143
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6 6v
Chapter15: Structure andFunction oftheNeurologicSystem .......................................................................148
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Chapter16:Pain,Temperature Regulation,Sleep, andSensory Function .......................................................159
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6 6v 6v 6v v
6 6v
Chapter 17:AlterationsinCognitive Systems,Cerebral Hemodynamics,and Motor Function ........................174
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6 6v 6v
Chapter18:Disordersofthe CentralandPeripheral Nervous Systems andthe Neuromuscular Junction
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6 6v 6v 6v 6v v
6 6v 6v
. ............................................................................................................................................................ 188
Chapter19:Neurobiologyof Schizophrenia,MoodDisorders,andAnxietyDisorders ......................................199
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6 6v 6v
Chapter 20: Alterations ofNeurologicFunction inChildren ...........................................................................206
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6
Chapter21:MechanismsofHormonalRegulation .......................................................................................213
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6
Chapter22:Alterations ofHormonalRegulation .........................................................................................222
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6
Chapter23:Obesity andDisordersof Nutrition .............................................................................................234
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Chapter 24: Structure andFunctionoftheReproductive Systems..................................................................239
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6 6v
Chapter25:Alterationsofthe Female Reproductive System .........................................................................249
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6 6v 6v 6v
Chapter26:Alterationsofthe Male Reproductive System.............................................................................259
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6 6v 6v 6v
Chapter27:Sexually Transmitted Infections................................................................................................265
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Chapter 28: Structure andFunction oftheHematologic System ....................................................................273
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6 6v
Chapter29:AlterationsofErythrocytes,Platelets, andHemostatic Function .................................................283
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6 v
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6 6v
, 3
y, 6vy,6vy,
Chapter30:AlterationsofLeukocyte andLymphoidFunction .......................................................................293
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6 6v 6v 6v
Chapter31:AlterationsofHematologic Functionin Children .........................................................................300
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6 6v 6v 6v
Chapter32:Structure andFunction oftheCardiovascular andLymphatic Systems .........................................311
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6 6v 6v 6v
Chapter33:AlterationsofCardiovascular Function......................................................................................324
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Chapter34:AlterationsofCardiovascular FunctioninChildren ......................................................................338
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6
Chapter35:StructureandFunctionofthePulmonary System ......................................................................346
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Chapter 36:Alterations ofPulmonary Function...........................................................................................356
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Chapter 37:Alterations ofPulmonaryFunctioninChildren ...........................................................................373
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6
Chapter38:Structure andFunction oftheRenal andUrologic Systems ...........................................................381
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Chapter 39: Alterations ofRenal and UrinaryTract Function .........................................................................391
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Chapter40:AlterationsofRenalandUrinaryTract Functionin Children ..........................................................401
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6 6v
Chapter41:StructureandFunctionoftheDigestive System .........................................................................409
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Chapter42:AlterationsofDigestive Function ..............................................................................................421
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Chapter43:AlterationsofDigestive Functionin Children ..............................................................................432
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Chapter 44: Structure andFunctionoftheMusculoskeletal System ..............................................................441
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Chapter 45:AlterationsofMusculoskeletal Function ...................................................................................453
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Chapter46:AlterationsofMusculoskeletal Functionin Children ...................................................................466
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Chapter47:Structure, Function, andDisordersoftheIntegument .................................................................475
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6
Chapter48:Alterationsofthe Integumentin Children ...................................................................................486
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Chapter49:Shock,MultipleOrganDysfunctionSyndrome, and BurnsinAdults ..............................................494
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Chapter50:Shock,MultipleOrganDysfunctionSyndrome, and BurnsinChildren ...........................................502
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6 6v 6v v
6 6v
, TestBank-Pathophysiology:TheBiologicBasisforDiseaseinAdultsandChildren(8th)
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Chapter01:CellularBiology v
6
MULTIPLECHOICE 6v
1. Whichstatementbestdescribesthecellularfunctionofmetabolicabsorption?
6v 6v 6v 6v 6v 6v 6v 6v 6v
a. Cellscanproduceproteins. 6v 6v 6v
b. Cellscansecretedigestiveenzymes. 6v 6v 6v 6v
c. Cellscantakeinandusenutrients. 6v 6v 6v 6v 6v
d. Cellscansynthesizefats. 6v 6v 6v
ANS: C 6 v
Inmetabolicabsorption,allcellstakeinandusenutrientsandothersubstancesfromtheir
6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v
surroundings. Theremainingoptions arenot inclusive in their descriptions of cellular
6v 6v 6v 6v 6v 6v 6v 6v 6v 6v
metabolicabsorption.
6v
PTS: 6 v 6 v 1 DIF: CognitiveLevel:Remembering 6v 6v
2. Whereismostofacell’sgeneticinformation,includingRNAandDNA,contained?
6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS: C 6 v
Thenucleuscontainsthenucleolus,asmalldensestructurecomposedlargelyofRNA,mostoft he cellular
6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v y, 6v
DNA, andtheDNA-bindingproteins, suchasthehistones, whichregulateitsactivity.
6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v
The mitochondria are responsible for cellular respiration and energyproduction.
6v 6 v 6 v 6 v 6 v 6v 6 v 6 v
6 Ribosomes’chieffunctionistoprovidesitesforcellularproteinsynthesis.Lysosomesfunctionas the
v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v y, 6v
intracellular digestive system.
6v 6v 6v
PTS: 6 v 6 v 1 DIF: CognitiveLevel: Remembering 6v 6v
3. Whichcomponentofthecellproduceshydrogenperoxide(H2O2)byusingoxygento
6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v
6v removehydrogen atoms from specific substrates in an oxidative reaction? 6v 6v 6v 6v 6v 6v 6v 6v
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS: B 6 v
PATHOPHYSIOLOGY
THEBIOLOGICBASISFORDISEASEINADULTSANDCHILDREN
6V 6V 6V 6V 6V 6V 6V 6V
8thEdition
6v
KathrynL.McCance,SueE.Huether
6v 6v 6v 6v
, 2
y, 6vy,6vy,
Contents
Chapter01:CellularBiology ............................................................................................................................4
6v v
6 6v
Chapter02:Altered Cellular andTissueBiology:Environmental Agents ...........................................................18
v
6 6v 6v 6v v
6 v
6 6v 6v
Chapter03:TheCellularEnvironment: Fluids andElectrolytes, Acids andBases ................................................31
v
6 v
6 v
6 6v 6v 6v 6v 6v 6v 6v
Chapter04:GenesandGeneticDiseases ........................................................................................................44
v
6 v
6 6v 6v v
6
Chapter05:Genes, Environment-Lifestyle,and Common Diseases .................................................................55
6v 6v 6v v
6 6v 6v
Chapter06:Epigenetics and Disease..............................................................................................................63
v
6 v
6 6v 6v
Chapter07:InnateImmunity:InflammationandWoundHealing.....................................................................68
v
6 v
6 6v 6v 6v v
6 6v
Chapter08:Adaptive Immunity ....................................................................................................................83
v
6 v
6 6v
Chapter09:Alterationsin Immunity andInflammation...................................................................................95
v
6 v
6 v
6 6v 6v 6v
Chapter10:Infection .................................................................................................................................108
v
6 v
6
Chapter11:StressandDisease ....................................................................................................................117
v
6 v
6 6v v
6
Chapter12:CancerBiology .........................................................................................................................124
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6 v
6 v
6
Chapter13:CancerEpidemiology ...............................................................................................................137
v
6 v
6 v
6
Chapter14:Cancerin Children ....................................................................................................................143
v
6 v
6 v
6 6v
Chapter15: Structure andFunction oftheNeurologicSystem .......................................................................148
6v 6v 6v 6v 6v 6v 6v
Chapter16:Pain,Temperature Regulation,Sleep, andSensory Function .......................................................159
v
6 v
6 v
6 6v 6v 6v v
6 6v
Chapter 17:AlterationsinCognitive Systems,Cerebral Hemodynamics,and Motor Function ........................174
6v 6v v
6 v
6 6 v 6v v
6 6v 6v
Chapter18:Disordersofthe CentralandPeripheral Nervous Systems andthe Neuromuscular Junction
6v v
6 v
6 6v v
6 6v 6v 6v 6v v
6 6v 6v
. ............................................................................................................................................................ 188
Chapter19:Neurobiologyof Schizophrenia,MoodDisorders,andAnxietyDisorders ......................................199
v
6 6v v
6 6v v
6 6v v
6 6v 6v
Chapter 20: Alterations ofNeurologicFunction inChildren ...........................................................................206
6v 6v y, 6v 6v 6v v
6
Chapter21:MechanismsofHormonalRegulation .......................................................................................213
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6 v
6 v
6 v
6
Chapter22:Alterations ofHormonalRegulation .........................................................................................222
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6 v
6 y, 6v v
6
Chapter23:Obesity andDisordersof Nutrition .............................................................................................234
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6 v
6 6v v
6 v
6 6v
Chapter 24: Structure andFunctionoftheReproductive Systems..................................................................239
6v 6v 6v 6v 6v v
6 6v
Chapter25:Alterationsofthe Female Reproductive System .........................................................................249
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6 v
6 v
6 6v 6v 6v
Chapter26:Alterationsofthe Male Reproductive System.............................................................................259
6v v
6 v
6 v
6 6v 6v 6v
Chapter27:Sexually Transmitted Infections................................................................................................265
6v 6v 6v 6v
Chapter 28: Structure andFunction oftheHematologic System ....................................................................273
6v 6v 6v 6v 6v v
6 6v
Chapter29:AlterationsofErythrocytes,Platelets, andHemostatic Function .................................................283
6v 6v v
6 v
6 v
6 6v v
6 6v
, 3
y, 6vy,6vy,
Chapter30:AlterationsofLeukocyte andLymphoidFunction .......................................................................293
v
6 v
6 v
6 v
6 6v 6v 6v
Chapter31:AlterationsofHematologic Functionin Children .........................................................................300
6v v
6 v
6 v
6 6v 6v 6v
Chapter32:Structure andFunction oftheCardiovascular andLymphatic Systems .........................................311
6v 6v 6v v
6 6v v
6 6v 6v 6v
Chapter33:AlterationsofCardiovascular Function......................................................................................324
v
6 6v v
6 v
6 6 v
Chapter34:AlterationsofCardiovascular FunctioninChildren ......................................................................338
6v v
6 v
6 v
6 6v 6v v
6
Chapter35:StructureandFunctionofthePulmonary System ......................................................................346
v
6 v
6 6v v
6 v
6 6v
Chapter 36:Alterations ofPulmonary Function...........................................................................................356
6v 6v y, 6v
Chapter 37:Alterations ofPulmonaryFunctioninChildren ...........................................................................373
6v v
6 y, 6v v
6 v
6
Chapter38:Structure andFunction oftheRenal andUrologic Systems ...........................................................381
6v 6v 6v v
6 6v v
6 6v v
6 6v
Chapter 39: Alterations ofRenal and UrinaryTract Function .........................................................................391
6v 6v y, 6v 6v 6v 6v 6v
Chapter40:AlterationsofRenalandUrinaryTract Functionin Children ..........................................................401
6v v
6 v
6 v
6 6v 6v v
6 6v v
6 6v
Chapter41:StructureandFunctionoftheDigestive System .........................................................................409
v
6 v
6 6v v
6 v
6 6v
Chapter42:AlterationsofDigestive Function ..............................................................................................421
6v 6v v
6 v
6 6v
Chapter43:AlterationsofDigestive Functionin Children ..............................................................................432
6v v
6 v
6 v
6 6v 6v 6v
Chapter 44: Structure andFunctionoftheMusculoskeletal System ..............................................................441
6v 6v 6v 6v 6v 6v 6v
Chapter 45:AlterationsofMusculoskeletal Function ...................................................................................453
6v 6v v
6 v
6 6v
Chapter46:AlterationsofMusculoskeletal Functionin Children ...................................................................466
6v 6v v
6 v
6 6v 6v 6v
Chapter47:Structure, Function, andDisordersoftheIntegument .................................................................475
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6 v
6 6v 6v v
6 v
6 v
6 v
6
Chapter48:Alterationsofthe Integumentin Children ...................................................................................486
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6 v
6 v
6 v
6 6v 6v 6v
Chapter49:Shock,MultipleOrganDysfunctionSyndrome, and BurnsinAdults ..............................................494
v
6 v
6 v
6 6v v
6 v
6 6v 6v v
6 6v
Chapter50:Shock,MultipleOrganDysfunctionSyndrome, and BurnsinChildren ...........................................502
v
6 v
6 v
6 6v v
6 v
6 6v 6v v
6 6v
, TestBank-Pathophysiology:TheBiologicBasisforDiseaseinAdultsandChildren(8th)
v
6 v
6 v
6 v
6 v
6 v
6 v
6 v
6 v
6 v
6 v
6 v
6 v
6 y , y, 6vy,
v 6v
6 6 v y 6 v , 6 v 4
Chapter01:CellularBiology v
6
MULTIPLECHOICE 6v
1. Whichstatementbestdescribesthecellularfunctionofmetabolicabsorption?
6v 6v 6v 6v 6v 6v 6v 6v 6v
a. Cellscanproduceproteins. 6v 6v 6v
b. Cellscansecretedigestiveenzymes. 6v 6v 6v 6v
c. Cellscantakeinandusenutrients. 6v 6v 6v 6v 6v
d. Cellscansynthesizefats. 6v 6v 6v
ANS: C 6 v
Inmetabolicabsorption,allcellstakeinandusenutrientsandothersubstancesfromtheir
6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v
surroundings. Theremainingoptions arenot inclusive in their descriptions of cellular
6v 6v 6v 6v 6v 6v 6v 6v 6v 6v
metabolicabsorption.
6v
PTS: 6 v 6 v 1 DIF: CognitiveLevel:Remembering 6v 6v
2. Whereismostofacell’sgeneticinformation,includingRNAandDNA,contained?
6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS: C 6 v
Thenucleuscontainsthenucleolus,asmalldensestructurecomposedlargelyofRNA,mostoft he cellular
6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v y, 6v
DNA, andtheDNA-bindingproteins, suchasthehistones, whichregulateitsactivity.
6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v
The mitochondria are responsible for cellular respiration and energyproduction.
6v 6 v 6 v 6 v 6 v 6v 6 v 6 v
6 Ribosomes’chieffunctionistoprovidesitesforcellularproteinsynthesis.Lysosomesfunctionas the
v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v y, 6v
intracellular digestive system.
6v 6v 6v
PTS: 6 v 6 v 1 DIF: CognitiveLevel: Remembering 6v 6v
3. Whichcomponentofthecellproduceshydrogenperoxide(H2O2)byusingoxygento
6v 6v 6v 6v 6v 6v 6v 6v 6v 6v 6v
6v removehydrogen atoms from specific substrates in an oxidative reaction? 6v 6v 6v 6v 6v 6v 6v 6v
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS: B 6 v