TEST BANK For Psychopharmacology Drugs the Brain and Behavior 3rd Edition By Meyer Nursing, Verified Chapters 1 - 20

, Test./Bank
to./accompany
Psychopharmacology,./Third./Edition
Meyer./•./Quenzer


Chapter./1:./Principles./of./Pharmacology

Multiple./Choice

1. refer(s)./to./specific./molecular./changes./that./occur./when./a./drug./binds./to./a./p
articular./target./site./or./receptor,./while
are./the./resulting./widespread./alterations./in./function.
a. Drug./action;./therapeutic./effects
b. Side./effects;./drug./effects
c. Therapeutic./effects;./side./effects
d. Drug./action;./drug./effects
Answer:./d
Textbook./Reference:./Pharmacology:./The./Science./of./Drug./Action

2. After./drug./administration./has./occurred,./the./amount./of./drug./in./the./blood./that./is./free./t
o./bind./at./specific./target./sites./is./referred./to./as
a. the./therapeutic./dose.
b. first-pass./effects.
c. bioavailability.
d. ED50.
Answer:./c
Textbook./Reference:./Pharmacokinetic./Factors./Determining./Drug./Action

3. The./specific./molecular./changes./that./occur./when./a./drug./binds./to./a./particular./target./sit
e./or./receptor./are./referred./to./as
a. drug./effects.
b. drug./action.
c. side./effects.
d. placebo./effects.
Answer:./b
Textbook./Reference:./Pharmacology:./The./Science./of./Drug./Action

4. Which./of./the./following./is./not./a./possible./explanation./for./placebo./effects?
a. Pavlovian./conditioning
b. Genetic./variation
c. Drug./competition
d. Expectation./of./outcome
Answer:./c
Textbook./Reference:./Pharmacology:./The./Science./of./Drug./Action



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,5. The administration./of./oxytocin./has./been./proposed./as./a./treatment./for./autism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer:./c
Textbook./Reference:./Pharmacokinetic./Factors./Determining./Drug./Action

6. Which./factor./does./not./affect./the./pharmacokinetics./of./a./drug?
a. Route./of./administration
b. Lipid./solubility
c. Depot./binding
d. Drug./action
Answer:./d
Textbook./Reference:./Pharmacokinetic./Factors./Determining./Drug./Action

7. First-pass./metabolism./occurs./when./drugs./are./taken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer:./a
Textbook./Reference:./Pharmacokinetic./Factors./Determining./Drug./Action

8. The./area./postrema./is./one./area./in./the./brain./where./the is./not./complete.
a. cerebrospinal./fluid
b. blood–brain./barrier
c. choroid./plexus
d. phospholipid./membrane
Answer:./b
Textbook./Reference:./Pharmacokinetic./Factors./Determining./Drug./Action

9. First-pass./metabolism./occurs./with./orally./administered./drugs./because
a. their./absorption./is./slowed./by./food.
b. drugs./absorbed./into./the./bloodstream./from./the./stomach./go./to./the./liver./on./the./way./t
o./general./circulation.
c. drugs./must./first./survive./the./acidic./environment./of./the./stomach.
d. salivary./enzymes./in./the./mouth./begin./the./process./of./metabolism.
Answer:./b
Textbook./Reference:./Pharmacokinetic./Factors./Determining./Drug./Action

10. Toxic./substances./in./the./blood./trigger./a./vomiting./response./by./activating./the
a. blood–brain./barrier.
b. choroid./plexus.
c. area./postrema.
d. median./eminence.




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, Answer:./c
Textbook./Reference:./Pharmacokinetic./Factors./Determining./Drug./Action

11. Drugs./administered./_ have./the./most./rapid./onset./of./action.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer:./d
Textbook./Reference:./Pharmacokinetic./Factors./Determining./Drug./Action

12. Ionization./of./a./drug./depends./on./the of./the./solution./and./the
of./the./drug.
a. pH;./pKa
b. pKa;./pH
c. concentration;./lipid./solubility
d. pH;./concentration
Answer:./a
Textbook./Reference:./Pharmacokinetic./Factors./Determining./Drug./Action

13. The./absorption./of./a./drug./depends./on./all./of./the./following./except
a. lipid./solubility.
b. ionization.
c. body./temperature.
d. the./concentration./of./the./drug.
Answer:./c
Textbook./Reference:./Pharmacokinetic./Factors./Determining./Drug./Action

14. Drugs./that./are should./be./avoided./by./women./of./childbearing./age.
a. teratogenic
b. able./to./cross./the./placental./barrier
c. psychoactive
d. highly./lipid-soluble
Answer:./a
Textbook./Reference:./Pharmacokinetic./Factors./Determining./Drug./Action

15. Agents./that./induce./developmental./abnormalities./in./a./fetus./are./known./as
a. psychoactive./drugs.
b. illicit./drugs.
c. teratogens.
d. placental./drugs.
Answer:./c
Textbook./Reference:./Pharmacokinetic./Factors./Determining./Drug./Action

16. Depot./binding./is./said./to./occur./when./drugs
a. bind./to./their./target./sites.




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