Full Test Bank - Rang & Dale's Pharmacology 10th
Edition, By James M. Ritter| Chapters 1-60| 2025 Latest
Update Version| Questions With Verified Answers
,SECTION 1; GENERAL PRINCIPLES ...........................................................................................................4
CHAPTER 1. WHAT IS PHARMACOLOGY? .........................................................................................................4
CHAPTER 2. HOW DRUGS ACT: GENERAL PRINCIPLES ........................................................................................8
CHAPTER 3. HOW DRUGS ACT: MOLECULAR ASPECTS ..................................................................................... 12
CHAPTER 4. HOW DRUGS ACT: CELLULAR ASPECTS - EXCITATION, CONTRACTION AND SECRETION ........................... 16
CHAPTER 5. HOW DRUGS ACT: BIOPHARMACEUTICALS AND GENE THERAPY ........................................................ 20
CHAPTER 6. CELL PROLIFERATION, APOPTOSIS, REPAIR AND REGENERATION ....................................................... 24
CHAPTER 7. CELLULAR MECHANISMS: HOST DEFENCE ..................................................................................... 28
CHAPTER 9. ABSORPTION AND DISTRIBUTION OF DRUGS ................................................................................. 39
CHAPTER 10. DRUG METABOLISM AND ELIMINATION ..................................................................................... 43
CHAPTER 11. PHARMACOKINETICS ............................................................................................................... 47
CHAPTER 12. INDIVIDUAL VARIATION, PHARMACOGENOMICS AND PERSONALISED MEDICINE ................................. 51
SECTION 2; CHEMICAL MEDIATORS ...................................................................................................... 54
CHAPTER 13. CHEMICAL MEDIATORS AND THE AUTONOMIC NERVOUS SYSTEM ................................................... 54
CHAPTER 14. CHOLINERGIC TRANSMISSION ................................................................................................... 58
CHAPTER 15. NORADRENERGIC TRANSMISSION .............................................................................................. 64
CHAPTER 16. 5-HYDROXYTRYPTAMINE AND PURINES...................................................................................... 69
CHAPTER 17. LOCAL HORMONES: HISTAMINE, LIPIDS, PEPTIDES AND PROTEINS ................................................... 75
CHAPTER 18. CANNABINOIDS ..................................................................................................................... 81
CHAPTER 19: NITRIC OXIDE AND RELATED MEDIATORS ................................................................................... 87
SECTION 3; DRUGS AFFECTING MAJOR ORGAN SYSTEMS .................................................................... 93
CHAPTER 20. THE HEART ........................................................................................................................... 93
CHAPTER 21: THE VASCULAR SYSTEM........................................................................................................... 98
CHAPTER 22. ATHEROSCLEROSIS AND LIPOPROTEIN METABOLISM ................................................................... 103
CHAPTER 23. HAEMOSTASIS AND THROMBOSIS ........................................................................................... 106
CHAPTER 24. HAEMOPOIETIC SYSTEM AND TREATMENT OF ANAEMIA ............................................................. 110
CHAPTER 25. ANTI-INFLAMMATORY AND IMMUNOSUPPRESSANT DRUGS ......................................................... 113
CHAPTER 26. SKIN .................................................................................................................................. 118
CHAPTER 27. EYE ................................................................................................................................... 124
CHAPTER 28. RESPIRATORY SYSTEM........................................................................................................... 129
CHAPTER 29. THE KIDNEY AND URINARY SYSTEM ......................................................................................... 134
CHAPTER 30. THE GASTROINTESTINAL TRACT............................................................................................... 139
CHAPTER 31. THE CONTROL OF BLOOD GLUCOSE AND DRUG TREATMENT OF DIABETES MELLITUS ........................ 145
CHAPTER 32. OBESITY ............................................................................................................................. 148
CHAPTER 33. THE PITUITARY AND THE ADRENAL CORTEX .............................................................................. 151
CHAPTER 34. THE THYROID ...................................................................................................................... 154
CHAPTER 35. THE REPRODUCTIVE SYSTEM .................................................................................................. 157
CHAPTER 36. BONE METABOLISM ............................................................................................................. 161
,SECTION 4; NERVOUS SYSTEM ........................................................................................................... 164
CHAPTER 37. CHEMICAL TRANSMISSION AND DRUG ACTION IN THE CENTRAL NERVOUS SYSTEM .......................... 164
CHAPTER 38. AMINO ACID TRANSMITTERS .................................................................................................. 166
CHAPTER 39. OTHER TRANSMITTERS AND MODULATORS............................................................................... 172
CHAPTER 40. NEURODEGENERATIVE DISEASES ............................................................................................. 176
CHAPTER 41. GENERAL ANAESTHETIC AGENTS ............................................................................................. 180
CHAPTER 42: HEADACHE ......................................................................................................................... 183
CHAPTER 43. ANALGESIC DRUGS ............................................................................................................... 188
CHAPTER 44. LOCAL ANAESTHETICS AND OTHER DRUGS AFFECTING SODIUM CHANNELS ..................................... 194
CHAPTER 45. ANXIOLYTIC AND HYPNOTIC DRUGS ........................................................................................ 200
CHAPTER 46. ANTIEPILEPTIC DRUGS ........................................................................................................... 209
CHAPTER 47. ANTIPSYCHOTIC DRUGS ......................................................................................................... 215
CHAPTER 48. ANTIDEPRESSANT DRUGS ...................................................................................................... 221
CHAPTER 49. PSYCHOACTIVE DRUGS .......................................................................................................... 227
CHAPTER 50. DRUG USE AND ADDICTION ................................................................................................... 233
SECTION 5; DRUGS USED FOR THE TREATMENT OF INFECTIONS AND CANCER................................... 239
CHAPTER 51. BASIC PRINCIPLES OF ANTIMICROBIAL CHEMOTHERAPY ............................................................... 239
CHAPTER 52. ANTIBACTERIAL DRUGS ......................................................................................................... 243
CHAPTER 53. ANTIVIRAL DRUGS................................................................................................................ 248
CHAPTER 54. ANTIFUNGAL DRUGS ............................................................................................................ 251
CHAPTER 55. ANTIPROTOZOAL DRUGS ....................................................................................................... 253
CHAPTER 56. ANTIHELMINTHIC DRUGS ....................................................................................................... 256
CHAPTER 57. ANTICANCER DRUGS ............................................................................................................. 262
SECTION 6; SPECIAL TOPICS ................................................................................................................ 269
CHAPTER 58. HARMFUL EFFECTS OF DRUGS ................................................................................................ 269
CHAPTER 59. LIFESTYLE DRUGS AND DRUGS IN SPORT .................................................................................. 276
CHAPTER 60: DRUG DISCOVERY AND DEVELOPMENT .................................................................................... 282
, SECTION 1; GENERAL PRINCIPLES
Chapter 1. What Is Pharmacology?
MULTIPLE CHOPICE
1. Which Of The Following Best Defines Pharmacology?
A. The Study Of Drug Prices And Marketing Strategies
B. The Study Of How Drugs Interact With Living Organisms To Affect Function
C. The Study Of The Biochemical Processes Of Disease
D. The Study Of Surgical Techniques For Drug Delivery
ANSWER; B
Pharmacology Is The Science Of Drugs, Including Their Composition, Uses, And Effects On The
Body. It Focuses On How Drugs Interact With Biological Systems To Affect Function, Making
Option B The Best Definition.
2. What Is The Primary Goal Of Pharmacology In Medicine?
A. To Prevent All Side Effects Of Drugs
B. To Create Drugs That Mimic All Endogenous Substances
C. To Understand Drug Mechanisms And Improve Therapeutic Effectiveness
D. To Design Drugs For Recreational Use
ANSWER; C
Pharmacology Aims To Understand The Mechanisms By Which Drugs Act, So They Can Be Used
Safely And Effectively In The Treatment Of Diseases. This Involves Optimizing Their Benefits
While Minimizing Adverse Effects.
3. Which Of The Following Disciplines Is Most Closely Related To Pharmacodynamics?
A. Drug Marketing
Edition, By James M. Ritter| Chapters 1-60| 2025 Latest
Update Version| Questions With Verified Answers
,SECTION 1; GENERAL PRINCIPLES ...........................................................................................................4
CHAPTER 1. WHAT IS PHARMACOLOGY? .........................................................................................................4
CHAPTER 2. HOW DRUGS ACT: GENERAL PRINCIPLES ........................................................................................8
CHAPTER 3. HOW DRUGS ACT: MOLECULAR ASPECTS ..................................................................................... 12
CHAPTER 4. HOW DRUGS ACT: CELLULAR ASPECTS - EXCITATION, CONTRACTION AND SECRETION ........................... 16
CHAPTER 5. HOW DRUGS ACT: BIOPHARMACEUTICALS AND GENE THERAPY ........................................................ 20
CHAPTER 6. CELL PROLIFERATION, APOPTOSIS, REPAIR AND REGENERATION ....................................................... 24
CHAPTER 7. CELLULAR MECHANISMS: HOST DEFENCE ..................................................................................... 28
CHAPTER 9. ABSORPTION AND DISTRIBUTION OF DRUGS ................................................................................. 39
CHAPTER 10. DRUG METABOLISM AND ELIMINATION ..................................................................................... 43
CHAPTER 11. PHARMACOKINETICS ............................................................................................................... 47
CHAPTER 12. INDIVIDUAL VARIATION, PHARMACOGENOMICS AND PERSONALISED MEDICINE ................................. 51
SECTION 2; CHEMICAL MEDIATORS ...................................................................................................... 54
CHAPTER 13. CHEMICAL MEDIATORS AND THE AUTONOMIC NERVOUS SYSTEM ................................................... 54
CHAPTER 14. CHOLINERGIC TRANSMISSION ................................................................................................... 58
CHAPTER 15. NORADRENERGIC TRANSMISSION .............................................................................................. 64
CHAPTER 16. 5-HYDROXYTRYPTAMINE AND PURINES...................................................................................... 69
CHAPTER 17. LOCAL HORMONES: HISTAMINE, LIPIDS, PEPTIDES AND PROTEINS ................................................... 75
CHAPTER 18. CANNABINOIDS ..................................................................................................................... 81
CHAPTER 19: NITRIC OXIDE AND RELATED MEDIATORS ................................................................................... 87
SECTION 3; DRUGS AFFECTING MAJOR ORGAN SYSTEMS .................................................................... 93
CHAPTER 20. THE HEART ........................................................................................................................... 93
CHAPTER 21: THE VASCULAR SYSTEM........................................................................................................... 98
CHAPTER 22. ATHEROSCLEROSIS AND LIPOPROTEIN METABOLISM ................................................................... 103
CHAPTER 23. HAEMOSTASIS AND THROMBOSIS ........................................................................................... 106
CHAPTER 24. HAEMOPOIETIC SYSTEM AND TREATMENT OF ANAEMIA ............................................................. 110
CHAPTER 25. ANTI-INFLAMMATORY AND IMMUNOSUPPRESSANT DRUGS ......................................................... 113
CHAPTER 26. SKIN .................................................................................................................................. 118
CHAPTER 27. EYE ................................................................................................................................... 124
CHAPTER 28. RESPIRATORY SYSTEM........................................................................................................... 129
CHAPTER 29. THE KIDNEY AND URINARY SYSTEM ......................................................................................... 134
CHAPTER 30. THE GASTROINTESTINAL TRACT............................................................................................... 139
CHAPTER 31. THE CONTROL OF BLOOD GLUCOSE AND DRUG TREATMENT OF DIABETES MELLITUS ........................ 145
CHAPTER 32. OBESITY ............................................................................................................................. 148
CHAPTER 33. THE PITUITARY AND THE ADRENAL CORTEX .............................................................................. 151
CHAPTER 34. THE THYROID ...................................................................................................................... 154
CHAPTER 35. THE REPRODUCTIVE SYSTEM .................................................................................................. 157
CHAPTER 36. BONE METABOLISM ............................................................................................................. 161
,SECTION 4; NERVOUS SYSTEM ........................................................................................................... 164
CHAPTER 37. CHEMICAL TRANSMISSION AND DRUG ACTION IN THE CENTRAL NERVOUS SYSTEM .......................... 164
CHAPTER 38. AMINO ACID TRANSMITTERS .................................................................................................. 166
CHAPTER 39. OTHER TRANSMITTERS AND MODULATORS............................................................................... 172
CHAPTER 40. NEURODEGENERATIVE DISEASES ............................................................................................. 176
CHAPTER 41. GENERAL ANAESTHETIC AGENTS ............................................................................................. 180
CHAPTER 42: HEADACHE ......................................................................................................................... 183
CHAPTER 43. ANALGESIC DRUGS ............................................................................................................... 188
CHAPTER 44. LOCAL ANAESTHETICS AND OTHER DRUGS AFFECTING SODIUM CHANNELS ..................................... 194
CHAPTER 45. ANXIOLYTIC AND HYPNOTIC DRUGS ........................................................................................ 200
CHAPTER 46. ANTIEPILEPTIC DRUGS ........................................................................................................... 209
CHAPTER 47. ANTIPSYCHOTIC DRUGS ......................................................................................................... 215
CHAPTER 48. ANTIDEPRESSANT DRUGS ...................................................................................................... 221
CHAPTER 49. PSYCHOACTIVE DRUGS .......................................................................................................... 227
CHAPTER 50. DRUG USE AND ADDICTION ................................................................................................... 233
SECTION 5; DRUGS USED FOR THE TREATMENT OF INFECTIONS AND CANCER................................... 239
CHAPTER 51. BASIC PRINCIPLES OF ANTIMICROBIAL CHEMOTHERAPY ............................................................... 239
CHAPTER 52. ANTIBACTERIAL DRUGS ......................................................................................................... 243
CHAPTER 53. ANTIVIRAL DRUGS................................................................................................................ 248
CHAPTER 54. ANTIFUNGAL DRUGS ............................................................................................................ 251
CHAPTER 55. ANTIPROTOZOAL DRUGS ....................................................................................................... 253
CHAPTER 56. ANTIHELMINTHIC DRUGS ....................................................................................................... 256
CHAPTER 57. ANTICANCER DRUGS ............................................................................................................. 262
SECTION 6; SPECIAL TOPICS ................................................................................................................ 269
CHAPTER 58. HARMFUL EFFECTS OF DRUGS ................................................................................................ 269
CHAPTER 59. LIFESTYLE DRUGS AND DRUGS IN SPORT .................................................................................. 276
CHAPTER 60: DRUG DISCOVERY AND DEVELOPMENT .................................................................................... 282
, SECTION 1; GENERAL PRINCIPLES
Chapter 1. What Is Pharmacology?
MULTIPLE CHOPICE
1. Which Of The Following Best Defines Pharmacology?
A. The Study Of Drug Prices And Marketing Strategies
B. The Study Of How Drugs Interact With Living Organisms To Affect Function
C. The Study Of The Biochemical Processes Of Disease
D. The Study Of Surgical Techniques For Drug Delivery
ANSWER; B
Pharmacology Is The Science Of Drugs, Including Their Composition, Uses, And Effects On The
Body. It Focuses On How Drugs Interact With Biological Systems To Affect Function, Making
Option B The Best Definition.
2. What Is The Primary Goal Of Pharmacology In Medicine?
A. To Prevent All Side Effects Of Drugs
B. To Create Drugs That Mimic All Endogenous Substances
C. To Understand Drug Mechanisms And Improve Therapeutic Effectiveness
D. To Design Drugs For Recreational Use
ANSWER; C
Pharmacology Aims To Understand The Mechanisms By Which Drugs Act, So They Can Be Used
Safely And Effectively In The Treatment Of Diseases. This Involves Optimizing Their Benefits
While Minimizing Adverse Effects.
3. Which Of The Following Disciplines Is Most Closely Related To Pharmacodynamics?
A. Drug Marketing
