Nursing Pharm One System Per Page with Side Effects
Medical Dosage Calculations and Pharmacology (Western Governors University)
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Nursing Pharmacology — One System Per Page (Complete Study
Sheets)
Cardiovascular
Beta-blockers (-olol)
Common Examples metoprolol, atenolol, propranolol, carvedilol
What it Does (Mechanism) Block stress signals (β1/β2) so the heart slows and squeezes softer.
Main Conditions Treated High BP, angina, arrhythmias, heart failure, post-MI.
Key Adverse Effects Bradycardia, hypotension, fatigue, depression; bronchospasm (non-selective).
Contraindications / Precautions Asthma/COPD (non-selective), heart block, acute decomp HF; caution in diabetes (masks hypoglycemia).
Monitoring & Labs HR/BP, signs of HF; in HF start low & go slow.
Major Interactions Other BP/HR-lowering meds; non-DHP CCBs ↑ bradycardia risk.
Antidote / Reversal Glucagon for severe β-blocker overdose; atropine for bradycardia.
Nursing Teaching Do not stop suddenly; check pulse/BP; report wheeze or dizziness.
Mnemonic / Pearl “LOL slows the heart.”
ACE Inhibitors (-pril)
Common Examples lisinopril, enalapril, captopril
What it Does (Mechanism) Block ACE so vessels relax and kidneys are protected.
Main Conditions Treated High BP, heart failure; kidney protection in diabetes.
Key Adverse Effects Dry cough, ↑K⁺, dizziness; rare angioedema.
Contraindications / Precautions Pregnancy, bilateral renal artery stenosis; caution with high K⁺.
Monitoring & Labs BP, kidney function (Cr), potassium.
Major Interactions K⁺ supplements/spironolactone ↑ K⁺; NSAIDs ↓ effect.
Antidote / Reversal Supportive (secure airway for angioedema).
Nursing Teaching Rise slowly; avoid K⁺ salt substitutes; report lip/tongue swelling.
Mnemonic / Pearl “PRIL = drop the pressure.”
ARBs (-sartan)
Common Examples losartan, valsartan
What it Does (Mechanism) Block angiotensin II so vessels stay relaxed.
Main Conditions Treated High BP, heart failure; ACE-cough alternative.
Key Adverse Effects ↑K⁺, dizziness (no cough).
Contraindications / Precautions Pregnancy; caution renal artery stenosis, hyperkalemia.
Monitoring & Labs BP, kidney function, potassium.
Major Interactions K⁺-sparing diuretics/supplements increase K⁺.
Antidote / Reversal Supportive.
Nursing Teaching Avoid in pregnancy; monitor BP/K⁺.
Mnemonic / Pearl “SARTAN sits on angiotensin.”
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Calcium Channel Blockers (-dipine (DHP) • diltiazem/verapamil (non-DHP))
Common Examples amlodipine, nifedipine; diltiazem, verapamil
What it Does (Mechanism) Block calcium entry → relax vessels; some slow the SA/AV node.
Main Conditions Treated High BP, angina; non-DHPs for rate control in arrhythmias.
Key Adverse Effects Hypotension, edema; constipation (verapamil); bradycardia/AV block (non-DHP).
Contraindications / Precautions Heart block/HFrEF for non-DHP; severe hypotension.
Monitoring & Labs BP/HR, edema, bowel pattern.
Major Interactions Grapefruit ↑ levels; with β-blockers ↑ bradycardia (non-DHP).
Antidote / Reversal Calcium, vasopressors for OD; pacing if severe brady.
Nursing Teaching Avoid grapefruit; increase fiber; check BP/HR.
Mnemonic / Pearl “No Ca²⁺, no squeeze.”
Diuretics—Loop ((-ide))
Common Examples furosemide, bumetanide
What it Does (Mechanism) Dump salt and water fast → more urine, less fluid.
Main Conditions Treated Edema (HF), high BP, hyperkalemia (adjunct).
Key Adverse Effects Low K⁺/Mg²⁺, dehydration, hypotension; ototoxicity (high IV dose).
Contraindications / Precautions Severe dehydration, sulfa allergy (relative).
Monitoring & Labs Electrolytes (K⁺/Mg²⁺), I&O, weight, BP.
Major Interactions Other BP-lowering meds; digoxin toxicity ↑ with low K⁺.
Antidote / Reversal Supportive; correct electrolytes.
Nursing Teaching Take in the morning; eat K⁺ foods; stand up slowly.
Mnemonic / Pearl “LOOP → LOts Of Pee.”
Diuretics—Thiazide (-thiazide)
Common Examples hydrochlorothiazide, chlorthalidone
What it Does (Mechanism) Block salt re-uptake (distal tubule) → gentle diuresis.
Main Conditions Treated High BP, mild edema.
Key Adverse Effects Low K⁺/Na⁺, dehydration; ↑glucose/uric acid.
Contraindications / Precautions Gout caution; sulfa allergy (relative).
Monitoring & Labs K⁺/Na⁺, BP, glucose, uric acid.
Major Interactions ↓ lithium clearance; adds to antihypertensives.
Antidote / Reversal Supportive.
Nursing Teaching AM dosing; monitor K⁺; watch sugars in diabetes.
Mnemonic / Pearl “THIAZIDE trims the pressure.”
K⁺-sparing (Aldosterone blockers) ((spironolactone/eplerenone))
Common Examples spironolactone, eplerenone
What it Does (Mechanism) Block aldosterone → keep K⁺, lose water.
Main Conditions Treated HF, high BP, hyperaldosteronism; acne/hirsutism (off-label).
Key Adverse Effects High K⁺, gynecomastia (spirono).
Contraindications / Precautions Hyperkalemia, severe kidney disease.
Monitoring & Labs K⁺, kidney function, BP.
Major Interactions K⁺ supplements/ACE/ARB ↑ K⁺.
Antidote / Reversal Supportive; treat hyperkalemia.
Nursing Teaching Avoid K⁺ salt substitutes; report palpitations.