Genetics Exam 3 Question Bank – Complete and Verified Collection with Answers

GENETICS EXAM 3 QUESTIONSBANK |
COMPLETE

The size of the human genome is approximately: - ACCURATE
ANSWERS✔✔ 3 billion base pairs



The model for semiconservative DNA replication was first
suggested/proposed by: - ACCURATE ANSWERS✔✔ Watson and Crick


Who's experiment first PROVED the semiconservative DNA replication
model? - ACCURATE ANSWERS✔✔ Messelson and Stahl


Which one of the following statements about DNA polymerase III of E.
coli is not true?
a) It synthesizes new DNA by adding to the 3' end of the growing chain
b) It requires a primer
c) it possesses a 5' exonuclease activity
d) It possesses a 3' exonucelase activity
e) It synthesizes the majority of the new DNA during chromosome
replication - ACCURATE ANSWERS✔✔ C) It possesses a 5' exonuclease
activity
-nick repair is done by DNA Pol I


Which of the following enzymes is considered a topoisomerase?

,a) DNA Pol I
b) helicase
c) primase
d) DNA gyrase
e) DNA ligase - ACCURATE ANSWERS✔✔ D) DNA gyrase


What are enzymes that regulate the overwinding or underwinding of
DNA? - ACCURATE ANSWERS✔✔ Topoisomerases


Which E. coli enzyme removes the primers used in DNA synthesis (5'
exonuclease activity)? - ACCURATE ANSWERS✔✔ DNA Polymerase I


One strand of the DNA duplex is synthesized in a continuous fashion.
The other is synthesized as a series of relatively short fragments. This
discontinuous method of DNA replication was first suggested by: -
ACCURATE ANSWERS✔✔ Reiji and Tuneko Okazaki



What is the region of the E. coli cell where the chromosome is found
called? - ACCURATE ANSWERS✔✔ nucleoid


Studies of the polytene chromosomes found in dipteran salivary gland
cells revealed that chromosome puffs were found: - ACCURATE
ANSWERS✔✔ in regions of high gene expression activity

,A DNA molecule is found to have MORE than 10.4 base pairs per turn
of the helix. It would be best described as being: - ACCURATE ANSWERS✔✔
negatively supercoiled


A DNA molecule is found to have LESS than 10.4 base pairs per turn of
the helix. It would be best described as being: - ACCURATE ANSWERS✔✔
positively supercoiled


What is a DNA strand that codes for two alleles called? - ACCURATE
ANSWERS✔✔ heteroduplex



Which histone is not part of the core particle octamer found in
eukaryotic chromatin? - ACCURATE ANSWERS✔✔ H1 (entry and exit to core
particle)


Which histones are core particles that form tetramers/octamers found in
eukaryotic cells? - ACCURATE ANSWERS✔✔ H2A
H2B
H3
H4


In the context of eukaryotic chromatin, the 11 nm fiber is: - ACCURATE
ANSWERS✔✔ A string of nucleosomes (nm)

, In the context of eukaryotic chromatin, the 2 nm fiber is: - ACCURATE
ANSWERS✔✔ The DNA double helix



In the context of eukaryotic chromatin, the 30 nm fiber is: - ACCURATE
ANSWERS✔✔ a coil of nucleosomes with about 6 per turn



In the context of eukaryotic chromatin, the 300 nm fiber is: - ACCURATE
ANSWERS✔✔ a repeatedly folded fiber



The 3' exonuclease activity of E. coli DNA polymerase I is very
important in that it allows the enzyme to: - ACCURATE ANSWERS✔✔
proofread


The 5' exonuclease activity of E. coli DNA polymerase I is very
important in that it allows the enzyme to: - ACCURATE ANSWERS✔✔ Carry
out nick translation during DNA repair


An example of a gene or genes commonly present in genomes at more
than one copy per haploid equivalent would be: - ACCURATE ANSWERS✔✔
rRNA genes


Today's DNA profiling technology relies upon loci called: - ACCURATE
ANSWERS✔✔ STRs (Short Tandem Repeats)

(microsatellites)