For the treatment of relapsing-remitting multiple sclerosis, the nurse practitioner knows
that:
a. First-line therapy typically involves an immunomodulator
b. Natalizumab is one of the safest drugs to use as initial therapy
c. A patient using interferon-beta products would have to have renal function monitored.
d. Fingolimod is given intravenously for patients with resistant remitting-relapsing multiple
sclerosis.
therapy begins with interferon-beta products (fingolimod, glatiramer, natalizumab) which
are immune modulator. Natalizumab limited (assoc w/ infections in brain) are used if others
don't work. Meds are hepatotoxic and need liver function monitoring. Fingolimod is 1st ORAL
disease modifying med approved for MS.
If a patient's abdomen is protuberant but soft and non-distended, what is the most likely
diagnosis?
a. A hernia
b. Enlarged liver
c. Enlarged spleen
d. Obesity
Of the following, the most common cause associated with disseminated intravascular
coagulation (DIC) is:
,a. Sepsis, with secretion of endotoxins from gram-negative or gram-positive
bacteria
b. Cancer or acute leukemia
c. The placement of foreign bodies, such as balloon catheter or other medical device in the
patient
d. Metabolic disturbances such as diabetes or hyperglycemic shock.
The most common site for hemorrhagic stroke to occur is in the:
a. Cerebrovascular arteries
b. Basal ganglia
c. Cerebellar hemispheres
d. Pons
b. Basal ganglia- occur most often here. Thrombotic strokes most common in
cerebrovascular arteries, not common for hemorrhagic to occur in Pons or cerebellar
hemispheres.
The nurse practitioner is considering the use of levofloxacin in a patient with a respiratory
tract infection. Which of the following in the patient's medical history would contraindicate
the use of levofloxacin?
a. Patient has a frequent history of urinary tract infections
b. Patient has a history positive for myasthenia gravis
c. Patient is 48 years old
,d. Patient has a history of vaginal yeast infections
You are talking to Jimmy about how he has been feeling lately. He starts to say that he has
been feeing tired and before he can finish his sentence, he falls asleep. You say his name and
he opens his eyes, but is inattentive and slow. How would you chart Jimmy's level of
consciousness?
a. Semi-coma
b. Obtunded
c. Delirious
d. Lethargic
Of the psychiatric syndromes below, which is correctly matched to its first-line drug of
choice as dictated by the Food and Drug Administration?
a. Obsessive Compulsive Disorder: Fluvoxamine
b. Social anxiety disorder: phenelzine
c. Panic disorder: Alprazolam
d. Post-traumatic stress disorder: trazodone
Which of these are unique features of aripiprazole (Abilify)?
a. It causes hyperprolactinemia and gynecomastia as side effects.
, b. It is a dopamine system stabilizer with affects against schizophrenia, mania, and agitation.
c. It causes agranulocytosis, which may be fatal; patient monitoring is necessary
d. It induces diabetes and myocarditis in certain patients
All of the following facial movements are still possible after a cerebrovascular accident
except:
a. Raising the eyebrows
b. Wrinkling the forehead
c. Raising both sides of the mouth
d. Closing both eyes
Which of the following is a characteristic of Somogyi effect?
a. It is characterized by an early morning rise in blood glucose, with no hypoglycemia during
the night. b. It is more common in type 2 diabetics
c. It presents with a combination of hypoglycemia followed by rebound hyperglycemia.
d. It is more common in elderly patients with poorly controlled blood sugars.
Nocturnal hypoglycemia stimulates hyperglycemia counter-regulation in am. No
hypoglycemia in night is Dawn phenomenon, more common in T1DM, esp children w/ T1DM