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FNP Board Review – Comprehensive Practice Test Study Guide | Verified Actual Questions & Answers (2024/2025 A+ Guide Solutions)

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The FNP Board Review Comprehensive Practice Test Study Guide (2024/2025 Edition) is a verified, A+ graded resource with updated exam-style questions and correct answers. It prepares candidates for the Family Nurse Practitioner (FNP) board certification exam by covering primary care, pharmacology, diagnostics, and patient management across the lifespan.The Family Nurse Practitioner (FNP) Board Certification Exam is a national exam administered by the AANP (American Academy of Nurse Practitioners) or ANCC (American Nurses Credentialing Center). Passing this exam certifies nurse practitioners to provide primary care across all age groups.

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Uploaded on
November 10, 2025
Number of pages
113
Written in
2025/2026
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FNP Board review questions and
answers 2024\2025 A+ Grade

A 24-year old, otherwise healthy college student presents with c/o cough x 6 weeks. She has tried
several OTC cough meds with no improvement. What is the most important information to consider
when building your differential diagnoses?

A) Her age

B) Family hx

C) Ineffectiveness of OTC cough medicines

D) Length of time she has been coughing
- correct answer D) Length of time she has been coughing



Why? This information helps you build your ddx

Acute cough < 3 weeks: bronchitis, sinusitis, PND, exacerbation of COPD/asthma, pneumonia,
pulmonary embolism



Chronic cough (>8 weeks) GERD and Asthma are most common causes, also consider infection (e.g.
pertussis, atypical pneumonia), ACE inhibitors, chronic bronchitis, bronchiectasis, lung ca)



According to the CDC, what drug class is considered first-line treatment for pertussis?

A) Sulfonamide

B) Tetracycline

C) Macrolide

D) Beta-lactam
- correct answer C) Macrolide antiobitic (e.g. Azithromycin, clarithromycin



Sulfonamides are second-line

,Match the antibiotics with the correct drug class:



1. Sulfonamide

2. Tetracycline

3. Macrolide

4. Beta-lactam




A. Doxycyline

B. Azithromycin

C. Penicillins

D.Trimethoprim-Sulfamethoxazole

E. Cephalosporin

F. Clarithromycin
- correct answer 1. Sulfonamide - D.Trimethoprim-Sulfamethoxazole (Bactrim)

2. Tetracycline - A. Doxycycline

3. Macrolide - B & F, Azithromycin and Clarithromycin



4. Beta-lactam - C & E, PCN and cephalosporins



What are the three most common bugs in community-acquired pneumonia?
- correct answer Streptococcus pneumoniae

Mycoplasma pneuomiae (atypical pathogen)

Chlamydophila pneumoniae (atypical pathogen)



What is the treatment for CAP caused by Strep pneumo?
- correct answer Respiratory quinolone (e.g. Levofloxacin, moxifloxacin, gemifloxacin) OR high-dose
amoxicillin OR amoxicillin with clavulanate

,What antibiotics are avoided in CAP caused by Strep pneumo due to high rates of resistance?
- correct answer Macrolides



What is the treatment for CAP caused by Mycoplasma pneumoniae?
- correct answer Macrolide OR doxycycline



What antibiotics are avoided in CAP caused by atypical pathogens?
- correct answer Beta-lactams (ineffective)



A 38-year old mother of two teenagers recently recovered from Mycoplasma pneumonia a couple of
weeks ago. She asks if she should get the "pneumonia shot." She takes levothyroxine 88 mcg daily for
hypothyroidism, but is otherwise healthy. How do you respond?

A) No, it's too soon after your infection

B) No, it's not indicated

C) Yes, you can get it in about a month

D) Yes you can get it today
- correct answer B) No, it's not indicated



An otherwise healthy adult without immunocompromise or multiple comorbid conditions is not a
"vulnerable population"



The pneumonia vaccine does not prevent mycoplasma pneumonia



According to GOLD, what is required to establish the diagnosis of COPD?
- correct answer Spirometry (FEV1/FVC ratio < 70%)



A 70-year old house painter reports a 4-week history of exertional dyspnea, chest tightness, and cough
for the past 3 months. He has never smoked. What diagnoses are included in your differential? Select 4.



A) Asthma

B) Angina

C) COPD

, D) GERD

E) Pneumonia

F) Tuberculosis

G) Heart Failure
- correct answer B) Angina

C) COPD

F) Tuberculosis

G) Heart failure



How do inhaled anticholinergics work to treat shortness of breath in COPD?

A) They cause bronchodilation in the lungs

B) They block the action of acetylcholine and prevent bronchoconstriction
- correct answer B) They block the action of acetylcholine and prevent bronchconstriction



Name a short-acting inhaled anticholinergic:
- correct answer Ipratropium (Atrovent)



Name a long-acting inhaled anticholinergic:
- correct answer Tiotropium (Spiriva)



How do inhaled betá-agonists work to treat shortness of breath in COPD?

A) They cause bronchodilation in the lungs

B) They block the action of acetylcholine and prevent bronchoconstriction
- correct answer A) They cause bronchodilation in the lungs



What are the only 2 inhaled short-acting beta agonists (SABAs):
- correct answer Albuterol and levalbuterol



Name an inhaled long-acting beta agonists (LABAs):
- correct answer Salmeterol (Serevent)

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