MOLECULAR IMMUNOLOGY, 10TH EDITION (ABBAS, 2022),
CHAPTER 1-21 | ALL CHAPTERS QUESTIONS & ANSWERS |
100% VERIFIED SOLUTIONS |QUESTIONS WITH CORRECT
ANSWERS 2025 LATEST UPDATE
Terms in this set (208) QUESTIONS VERIFIED ANSWERS
1) The germinal centers found in the cortical region of contains large populations
lymph nodes and the peripheral region of splenic of B lymphocytes and
periarteriolar lymphatic tissue: plasma cells
2) Balance between TH1 and TH2 cell activation tuberculoid leprosy will
determines outcome of intracellular infections. Thus, occur in patients with a
in case of Mycobacterium leprae infection: prominent TH1 response
3) The initiation of T cell responses requires multiple CD4 or CD8 molecules
receptors on the T cells recognizing ligands on
APCs. The MHC molecule located around the
peptide-binding cleft is recognized by the:
4) The edema occurring in the inflammatory process is neural impulse by the
, the result of all the following factors EXCEPT: sympathetic system and
vasoconstriction
5) Toll-Like Receptors (TLR): recognize pathogen-
associated molecular
patterns (PAMPs) on
selective microorganisms
6) The initiation of T cell responses requires multiple CD3 and δ molecules
receptors on the T cells recognizing ligands on
APCs. The T cell receptor transduction molecule(s)
is(are) conducted by:
7) Which of the following is considered a primary thymus
lymphoid organ?
8) Immediate activation of the B lymphocytes MHC class II molecules
following contact with the antigen involves all of the
following molecules EXCEPT:
9) Immunologic memory refers to: changes in adaptive
immune responses with
subsequent encounters
with antigen
10) Both, naive mature effector T lymphocytes migrate L-selectin
differently in their lives. Naive T cells express which
adhesion molecule to mediate their migration into
lymph nodes through specialized vessels called high
, endothelial venues (HEVs)?
11) The main consequences of complement activation producing 2nd signal for
are all of the following EXCEPT: macrophage activation
12) 'Langerhans Cells' which play a role in the immune dendritic cells located
system are: mainly in the epidermis
13) All of the following cells results in the germinal short-lived plasma cells
center reaction of the follicles (B lymphocyte zone)
EXCEPT:
14) The antigen recognition on the T cells is mediated the Variable (v) regions of
by: α and β chains
15) The T-cell receptor: recognizes antigen
fragments via the α and β
chains
16) According to the clonal selection hypothesis, which Clones of lymphocytes
of the following is CORRECT? specific for antigens
develop prior to exposure
to the antigens
17) Which of the following best describes the T- IT is the response of
dependent antibody response? follicular B lymphocytes
to a protein antigen and
characterized by isotope-
switched, high affinity
antibodies; memory B
, cells, long lived plasma
cells
18) MHC class II molecules contain: One α chain and one β
chain
19) The inflammatory cytokines will cause Langerhans antigen presentation to the
cells in the epidermis to perform all of the following T cells in the follicles of
EXCEPT: the lymph nodes
20) The phases and order of the specific or acquired recognition phase;
immune responses are: activation phase; effector
phase; homeostasis phase;
memory phase
21) A naive CD4+ T cell may differentiate into subsets CD4+ T cell TH1 subset
that produce different cytokines that recruit and
activate different cell types. The IFN-γ is produced
mainly by:
22) TH1 subset effector cells that aid in cell mediated CD40L-CD40 interaction
immune response activate the macrophage and B and IFN-γ
lymphocytes by:
23) The diversity of antigen receptors produced by the both combinatorial
use of different combinations of V, D, and J gene diversity and junctional
segments in different clones of lymphocytes is the diversity
result of:
24) All of the following statements about the B-cell recognizes antigen