NR 565 Midterm 2025 exam questions
with correct answers graded a+ assured
excel!!
WheneprescribingeMedications,eweemusteunderstandethatetheeliverefunctionedeclinesewitheageed/tewhat?
A.eEnlargedeLiver
B.eDecreasedebloodeflowetoeliver
C.eIncreasedeactivityeofetheehepaticeenzymese-eeCORRECTeANSWERSB.eDecreasedebloodeflowetoeliver
Ane82eyoemaleevisitsetheeclinicecomplainingethatehisepainemedse"takeeforever"etoeworkeaftereheetakesehisepi
ll.eWhateareepossibleereasonseyouecaneexplainetoehimeasetoewhyethisemayebeehappening.
A.ePerhapseweeneedetoeincreaseeyouredose
B.eSometimeseaseyouegeteolder,eabsorptionemayebeeslowereresultingeineaedelayederesponse
C.eAseweegeteolder,etheegastriceacidedecreaseseandemayedelayeabsorptione-
eeCORRECTeANSWERSB.eSometimeseaseyouegeteolder,eabsorptionemayebeeslowereresultingeineaedelayederes
ponse
C.eAseweegeteolder,etheegastriceacidedecreaseseandemayedelayeabsorption
RAeCharacteristics
Onset
Affectedepopulation
Location
Jointestiffnesseduration
SxSe-eeCORRECTeANSWERSweeks-months
women>men
commonehands,efeet,e&ewrists
>60emineineAM
,locale&esys.
OAeCharacteristicse
Onset
Affectedepopulation
Location
Jointestiffnesseduration
SxSe-eeCORRECTeANSWERSyears
mene&eWomeneequally
Handse&eweightebaringejointse
<30mineineAM
typicallyelocal
WhatemighteyoueexpectetoefindeinetheesynovialefluideofeaeptewitheOAe-eeCORRECTeANSWERSMildeleukocytes
WhatemighteyoueexpectetoefindeinetheesynovialefluideofeaeptewitheRAe-
eeCORRECTeANSWERSCloudyewitheleukocytes
GoalseofeTxeforeRAe-eeCORRECTeANSWERSSxsereliefe(pain,estiffness,einflammation,
maintainingejointefxneandeROM
minimizeesystemiceinvolvement
delayeprogression
TypicalepharmeTxseforeRAe-
eeCORRECTeANSWERSNSAIDs,esystemicesteroids,eantimalarials,eantimetabolites,eandebiologics
BaselineeassessmentedataebeforeestartingeDMARDe-
eeCORRECTeANSWERSLiver,ePG,eserumecreatinine,eCBCewithediff,esxseofeinfxne(TBe&ehepatits),eHxe&ephysical
,erenalestatus,e&emalignancies
, SignificantebaselineedataeforeSulfasalazinee-eeCORRECTeANSWERSCXR,epulmonaryeandeneuroestatus
SignificantebaselineedataeforeLeflunomidee-eeCORRECTeANSWERSCXR,eBPe&epulmonaryestatus
SignificantebaselineedataeforeMehtotrexatee-eeCORRECTeANSWERSCXR,ePulmonaryeandeGIestatus
Significantebaselineedataeforehydroxychloroquinee-
eeCORRECTeANSWERSOphthalmologice&ecardiaceexame(ECGeifeindicated)
ConventionaleDMARDs-eexamplese-eeCORRECTeANSWERSMethotrexate,ehydroxychloroquine,esulfsalazine
BiologiceDMARDS-eexamplese-eeCORRECTeANSWERSadalimumab,eetanercept,egolimumab
"-mab"s
MOAeofemethotrexatee-eeCORRECTeANSWERSfoliceacideantagoniste->inhibitselymphocyteeproliferation
WithinehowemanyemonthseofeRAediagnosiseshouldeMethotrexateebeestartedeandewhy?e-
eeCORRECTeANSWERS3emonthseofediagnosis
delayejointedegeneration
WhateroutineemonitoringeiseneededeforeMethotrexate?e-eeCORRECTeANSWERSPeriodicelivere&erenalefxn
Whatebloodeleveledoeweeexpectetoeseeeelevatedeineaepatientewithegout?e-eeCORRECTeANSWERSUriceacid
FirstelineeTxeforegoute-eeCORRECTeANSWERSCorticosteroids,eNSAIDs,eoreColchicine
with correct answers graded a+ assured
excel!!
WheneprescribingeMedications,eweemusteunderstandethatetheeliverefunctionedeclinesewitheageed/tewhat?
A.eEnlargedeLiver
B.eDecreasedebloodeflowetoeliver
C.eIncreasedeactivityeofetheehepaticeenzymese-eeCORRECTeANSWERSB.eDecreasedebloodeflowetoeliver
Ane82eyoemaleevisitsetheeclinicecomplainingethatehisepainemedse"takeeforever"etoeworkeaftereheetakesehisepi
ll.eWhateareepossibleereasonseyouecaneexplainetoehimeasetoewhyethisemayebeehappening.
A.ePerhapseweeneedetoeincreaseeyouredose
B.eSometimeseaseyouegeteolder,eabsorptionemayebeeslowereresultingeineaedelayederesponse
C.eAseweegeteolder,etheegastriceacidedecreaseseandemayedelayeabsorptione-
eeCORRECTeANSWERSB.eSometimeseaseyouegeteolder,eabsorptionemayebeeslowereresultingeineaedelayederes
ponse
C.eAseweegeteolder,etheegastriceacidedecreaseseandemayedelayeabsorption
RAeCharacteristics
Onset
Affectedepopulation
Location
Jointestiffnesseduration
SxSe-eeCORRECTeANSWERSweeks-months
women>men
commonehands,efeet,e&ewrists
>60emineineAM
,locale&esys.
OAeCharacteristicse
Onset
Affectedepopulation
Location
Jointestiffnesseduration
SxSe-eeCORRECTeANSWERSyears
mene&eWomeneequally
Handse&eweightebaringejointse
<30mineineAM
typicallyelocal
WhatemighteyoueexpectetoefindeinetheesynovialefluideofeaeptewitheOAe-eeCORRECTeANSWERSMildeleukocytes
WhatemighteyoueexpectetoefindeinetheesynovialefluideofeaeptewitheRAe-
eeCORRECTeANSWERSCloudyewitheleukocytes
GoalseofeTxeforeRAe-eeCORRECTeANSWERSSxsereliefe(pain,estiffness,einflammation,
maintainingejointefxneandeROM
minimizeesystemiceinvolvement
delayeprogression
TypicalepharmeTxseforeRAe-
eeCORRECTeANSWERSNSAIDs,esystemicesteroids,eantimalarials,eantimetabolites,eandebiologics
BaselineeassessmentedataebeforeestartingeDMARDe-
eeCORRECTeANSWERSLiver,ePG,eserumecreatinine,eCBCewithediff,esxseofeinfxne(TBe&ehepatits),eHxe&ephysical
,erenalestatus,e&emalignancies
, SignificantebaselineedataeforeSulfasalazinee-eeCORRECTeANSWERSCXR,epulmonaryeandeneuroestatus
SignificantebaselineedataeforeLeflunomidee-eeCORRECTeANSWERSCXR,eBPe&epulmonaryestatus
SignificantebaselineedataeforeMehtotrexatee-eeCORRECTeANSWERSCXR,ePulmonaryeandeGIestatus
Significantebaselineedataeforehydroxychloroquinee-
eeCORRECTeANSWERSOphthalmologice&ecardiaceexame(ECGeifeindicated)
ConventionaleDMARDs-eexamplese-eeCORRECTeANSWERSMethotrexate,ehydroxychloroquine,esulfsalazine
BiologiceDMARDS-eexamplese-eeCORRECTeANSWERSadalimumab,eetanercept,egolimumab
"-mab"s
MOAeofemethotrexatee-eeCORRECTeANSWERSfoliceacideantagoniste->inhibitselymphocyteeproliferation
WithinehowemanyemonthseofeRAediagnosiseshouldeMethotrexateebeestartedeandewhy?e-
eeCORRECTeANSWERS3emonthseofediagnosis
delayejointedegeneration
WhateroutineemonitoringeiseneededeforeMethotrexate?e-eeCORRECTeANSWERSPeriodicelivere&erenalefxn
Whatebloodeleveledoeweeexpectetoeseeeelevatedeineaepatientewithegout?e-eeCORRECTeANSWERSUriceacid
FirstelineeTxeforegoute-eeCORRECTeANSWERSCorticosteroids,eNSAIDs,eoreColchicine
