NR 565 2.pdf

NR 565 - ADVANCED
PHARMACOLOGY MIDTERM –
CHAMBERLAIN QUESTIONS WITH
CORRECT ANSWERS GRADED A+
FOR 2025-2026 ASSURED EXCEL!!
Duringswhatstrimestersissaspregnantswomansmostsatsrisksforsadversesdrugsreactionsswithspotentialslongster
msconsequences?s-ssCORRECTsANSWERS1ststrimesters(fetussmostsatsrisksd/tsrapidsgrowth)



WhatsissBEERSscriteria?s-
ssCORRECTsANSWERSRecommendationssofsmedicationssinappropriatesforselderlys(65sandsolder),sprescribe

rsultimatelysdecides



WhatsissthesCYP450s(cytochromesP450)s-
ssCORRECTsANSWERSliversenzymessystemswheresmedicationssaresmetabolized,scanseithersbesinducerssorsin

hibitorssandscreatesdrug-drugsinteractions



CYP450sinducerss-
ssCORRECTsANSWERSSpeedsupsmetabolismsofsdrugss(drugsissclearedsfaster),sdrugshasslesserseffects(decreas

esbloodslevelssofsdrug),selevatesCYP450senzymes



CYP450sinducersspneumonics-ssCORRECTsANSWERS"BullshitsCrapsGPSsINDUCESsrage"



CYP450sinducersdrugsnamess-
ssCORRECTsANSWERSBarbituates,sStsJohnswort,sCarbamazepine,srifampin,salcohol,sphenytoin,sgriseofulvin,

sphenobarbital,ssulfonylureas




CYP450sinhibitorss-ssCORRECTsANSWERSinhibitsmetabolism,sincreasesbloodslevelssofsmedications



CYP450spneumonics-
ssCORRECTsANSWERS"VISAscreditscardsdebtsINHIBITSsspendingsonsdesignersslikesCKstoslooksGQ"

,CYP450sinhibitorssdrugsnamess-
ssCORRECTsANSWERSValproate,sisoniazid,ssulfonamides,samiodarone,schloramphenicol,sketoconazole,sgra

pefruitsjuice,squinidine



Physiologicalschangessduringspregnancysthatsimpactspharmacodynamicssandspharmacokineticspropertiess
ofsdrugs?s-ssCORRECTsANSWERSincreasesglomerularsfiltrationsratesleadsstosincreasesdurgsexcretions

increaseshepaticsmetabolism

decreasestonesandsmotilitysofsbowel

increasesdrugsabsorption



Examplessofsmedicationssthatscansbesteratogenics-
ssCORRECTsANSWERSAntiepilepticsdrugs,santimicrobialsssuchsasstetracyclinessandsfluoroquinolones,svitami

nsAsinslargesdoses,ssomesanticoagulants,sandshormonalsmedicationsssuchsassdiethylstilbestrols(DES).



Howsissabsorptionsofsintramuscularsmedicationssdifferentsinsneonates?s-
ssCORRECTsANSWERSslowsandserraticsduestoslowsbloodsflowsinsmusclessfirstsfewsdayssofslife




Whysissabsorptionsofsmedicationsinsthesstomachsincreasedsinsinfancy?s-
ssCORRECTsANSWERSdelayedsgastricsemptying




Somesmedicationssthatsshouldsbesavoidedsinsthespediatricspatient?s-
ssCORRECTsANSWERSglucocorticoids,sdiscolorationsofsdevelopingsteethswithstetracyclines,sandskernicteruss

withssulfonamides,slevofloxacins(antibiotics)s

aspirins(Severesintoxicationsfromsacutesoverdose)



whatsshouldsbesincludedsinsmedicationsadministrationspatientseducation?s-
ssCORRECTsANSWERSdosagessizesandstiming



routesandstechniquesofsadministration

durationsofstreatment

drugsstorage

naturesandstimescoursesofsdesiredsresponses

,naturesandstimescoursesofsadversesresponses

finishstakingsantibiotic



Whatsaressomesthingssthatsputstheselderlyspatientsatshighersrisksforsadversesdrugsreactions?s-
ssCORRECTsANSWERSreducedsrenalsfunctions



polypharmacys(thesusesofsfivesorsmoresmedicationssdaily)

greatersseveritysofsillness

presencesofscomorbidities

usesofsdrugssthatshavesaslowstherapeuticsindexs(e.g.,sdigoxin)

increasedsindividualsvariationssecondarystosalteredspharmacokinetics

inadequatessupervisionsofslong-termstherapy

poorspatientsadherence



Howscanshealthcaresproviderssdecreaseslikelihoodsofsanselderlyspatientsexperiencingsansadversesdrugsreact
ion?s-ssCORRECTsANSWERSobtainingsasthoroughsdrugshistorysthatsincludessover-the-countersmedications

consideringspharmacokineticsandspharmacodynamicsschangessduestosage

monitoringsthespatient'ssclinicalsresponsesandsplasmasdrugslevels

usingsthessimplestsregimenspossible

monitoringsforsdrug-drugsinteractionssandsiatrogenicsillness

periodicallysreviewingsthesneedsforscontinuedsdrugstherapy

encouragingsthespatientstosdisposesofsoldsmedications

takingsstepsstospromotesadherencesandstosavoidsdrugssonsthesBeersslist



Howscanswespromotesmedicationsadherenceswithselderlyspatients?s-
ssCORRECTsANSWERSsimplifyingsdrugsregimens



providingsclearsandsconcisesverbalsandswrittensinstructions

usingsansappropriatesdosagesform

clearlyslabelingsandsdispensingseasy-to-openscontainers

developingsdailysreminders

monitoringsfrequently

, affordabilitysofsdrugs

supportssystems



Whysdosnitratessneedstosbestakensnoslatersthans4sPM?s-
ssCORRECTsANSWERSNeedsnitratesfreesintervalssostolerancesdoesn'tsdevelop




Ninesfactorssthatsimpactsoutcomesofsmedication?s-ssCORRECTsANSWERSGendersandsrace

Geneticssandspharmacogenomics

Variabilitysinsabsorption

placeboseffect

Tolerance

patho

age

bodyweight



Dosyousneedsinformedsconsentsforsgeneticstesting?s-ssCORRECTsANSWERSyes



WhatsissthespurposesofsthesGeneticsInformationsNon-DiscriminatorysAct?s-
ssCORRECTsANSWERSProtectsspatientssfromsdiscriminationsbysemployerssandsinsurancesproviderssbasedso

nsgeneticsinformation



Differencesbetweenspracticesauthoritysandsprescriptivesauthority?s-
ssCORRECTsANSWERSPracticesauthoritysrefersstosthesnursespractitioner'ssabilitystospracticeswithoutsphysici

ansoversight,swhereassprescriptivesauthoritysrefersstosthesnursespractitioner'ssauthoritystosprescribesmedi
cationssindependentlysandswithoutslimitations.



Whosregulatessprescriptivesauthority?s-
ssCORRECTsANSWERSthesjurisdictionsofsashealthsprofessionalsboard.sThissmaysbesthesStatesBoardsofsNursing

,sthesStatesBoardsofsMedicine,sorsthesStatesBoardsofsPharmacy,sassdeterminedsbyseachsstate.



Whatsissscopesofspracticesdeterminedsby?s-
ssCORRECTsANSWERSissdeterminedsbysstatespracticesandslicensureslaws.