NR565 ADVANCED PHARMACOLOGY MIDTERM EXAM STUDY GUIDE EXAM QUESTIONS WITH

NR565 ADVANCED PHARMACOLOGY
MIDTERM EXAM STUDY GUIDE EXAM
QUESTIONS WITH CORRECT
ANSWERS GRADED A+ FOR 2025-
2026 ASSURED EXCEL!!
DrugswthatwAPRNswcanwprescribew-wwCORRECTwANSWERSSchedulew3-5wdrugs



DeterminedwbywStatewBoardswofwNursing,wMedicine,wandwPharmacyw-
wwCORRECTwANSWERSPrescriptivewauthoritywregulation




Leadswtowfewerwtreatmentwoptionswforwpatients,wrequiringwthemwtowfindwproviderswwithwauthorityw-
wwCORRECTwANSWERSLimitedwprescriptivewauthoritywimpact




Understandingwprescribedwdrugs,wtheirweffects,wcontraindications,wandwensuringwcorrectwdosagesw-
wwCORRECTwANSWERSKeywresponsibilitieswofwprescribing




AcronymwforwCYP450wenzymewinducers:wBarbiturates,wSt.wJohn'swWort,wCarbamazepine,wRifampin,wAlcoh
ol,wPhenytoin,wGriseofulvin,wPhenobarbital,wSulfonylureasw-
wwCORRECTwANSWERSBSCRAPwGPSwIncudeswRage




Amountwofwactivewdrugwreachingwsystemicwcirculationwfromwadministrationwsitew-
wwCORRECTwANSWERSBioavailability




Includewforgetfulness,wlackwofwplanning,wcost,wdissatisfaction,wandwalteredwdosingw-
wwCORRECTwANSWERSReasonswforwmedicationwnonadherence




Absorptionwiswslowwinwneonateswduewtowlowwmusclewbloodwflow;wabsorptionwbecomeswrapidwinwearlywinfa
ncyw-wwCORRECTwANSWERSIMwadministrationwinwneonateswandwinfants

, Gastricwemptyingwtimewiswprolongedwandwirregularwinwearlywinfancy,waffectingwdrugwabsorptionw-
wwCORRECTwANSWERSOralwadministrationwinwneonates/infants




Basedwonwbodywsurfacewareaw(BSA)wcalculationw-
wwCORRECTwANSWERSDosagewdeterminationwforwpediatricwpatients




Stepswincludewdefiningwthewproblem,wsettingwtherapeuticwobjectives,wchoosingwtreatment,wverifyingwitsws
uitability,wstartingwtreatment,wgivingwinformation,wandwmonitoringwtreatmentw-
wwCORRECTwANSWERSGuidingwprincipleswforwprescribers




ExampleswincludewValproate,wIsoniazid,wSulfonamides,wAmiodarone,wChloramphenicol,wKetoconazole,wGr
apefruitwjuice,wQuinidinew-wwCORRECTwANSWERSCYP450winhibitors



Basiswforwprescribingwdecisions,wconsideringwdrugwinteractionswandweffectswonwtargetwreceptorsw-
wwCORRECTwANSWERSPharmacokineticswandwpharmacodynamics




Toolwidentifyingwinappropriatewmedicationwusewinwolderwadults,wcautioningwagainstwcertainwdrugswandwint
eractionsw-wwCORRECTwANSWERSBeer'swCriteria



Includewadversewdrugwevents,wincreasedwhealthcarewinteractions,wcognitivewimpairment,wreducedwadhere
nce,wfalls,wandwmortalityw-wwCORRECTwANSWERSImpactswofwpolypharmacy



Theywdecreasewmedicationwmetabolismw-wwCORRECTwANSWERSCYP450winhibitorswfunction



Maywcausewtoxicitywifwenzymeswarewinactiveworwineffectivenesswifwenzymeswarewoveractivew-
wwCORRECTwANSWERSCYP450winhibitorswconsequences




OccurswwhenwCYP2D6walleleswhavewinactivatingwmutations,wleadingwtowenzymewsynthesiswwithwimpairedw
orwnowactivityw-wwCORRECTwANSWERSPoorwmetabolismwphenotype



Ensureswsafety,wefficiency,wandwsecuritywofwhumanwandwveterinarywdrugs,wbiologicalwproducts,wandwmedi
calwdevicesw-wwCORRECTwANSWERSUSwFDAwregulation