Final Exam Review: NR565 / NR 565
(Latest Update )
Advanced Pharmacology
Fundamentals | Questions and
Answers | Grade A | 100% Correct –
Chamberlain
Question:
GERD: PPI mechanism of actions
Answer:
inhibits H+,K+-ATPase (proton pump) that generates gastric acid
Question:
GERD: discontinuation of PPI
Answer:
-should be limited to 4-8 weeks but relapse symptoms typically occur within
6 to 12 months
-with severe GERD, long-term therapy is recommended
,Question:
GERD: PPI adverse effects
Answer:
fracture, pneumonia, acid rebound, C. diff
Question:
GERD: PPI therapeutic use
Answer:
suppress gastric acid secretion
Question:
GERD: therapeutic use of omeprazole
Answer:
short-term therapy of ulcers, erosive esophagitis, and GERD
long-term use for hypersecretory states
,Question:
GERD: sucralfate drug interactions
Answer:
-can impede absorption of phenytoin, theophylline, digoxin, warfarin, and
fluoroquinolone antibiotics
-administer at least 2 hours from other drugs
Question:
GERD: sucralfate mechanism of action
Answer:
under mildly acidic conditions, sucralfate undergoes polymerization resulting
in a viscid and very sticky gel that adheres to the ulcer crater, creating a
barrier
Question:
PUD: H. pylori treatments
Answer:
combo of clarithromycin, amox, bismuth, metronidazole, and a tetracycline
plus a PPI
, Question:
PUD: antacid adverse effects
Answer:
constipation and diarrhea, sodium loading leading to HTN or HF
exacerbation
Question:
PUD: cimetidine adverse effects
Answer:
antiandrogenic effects, CNS effects (hallucinations, confusion or
depression/excitation), pneumonia
Question:
PUD: cimetidine mechanism of action
Answer:
selectively blocks H2 receptors to decrease gastric acid secretion
(Latest Update )
Advanced Pharmacology
Fundamentals | Questions and
Answers | Grade A | 100% Correct –
Chamberlain
Question:
GERD: PPI mechanism of actions
Answer:
inhibits H+,K+-ATPase (proton pump) that generates gastric acid
Question:
GERD: discontinuation of PPI
Answer:
-should be limited to 4-8 weeks but relapse symptoms typically occur within
6 to 12 months
-with severe GERD, long-term therapy is recommended
,Question:
GERD: PPI adverse effects
Answer:
fracture, pneumonia, acid rebound, C. diff
Question:
GERD: PPI therapeutic use
Answer:
suppress gastric acid secretion
Question:
GERD: therapeutic use of omeprazole
Answer:
short-term therapy of ulcers, erosive esophagitis, and GERD
long-term use for hypersecretory states
,Question:
GERD: sucralfate drug interactions
Answer:
-can impede absorption of phenytoin, theophylline, digoxin, warfarin, and
fluoroquinolone antibiotics
-administer at least 2 hours from other drugs
Question:
GERD: sucralfate mechanism of action
Answer:
under mildly acidic conditions, sucralfate undergoes polymerization resulting
in a viscid and very sticky gel that adheres to the ulcer crater, creating a
barrier
Question:
PUD: H. pylori treatments
Answer:
combo of clarithromycin, amox, bismuth, metronidazole, and a tetracycline
plus a PPI
, Question:
PUD: antacid adverse effects
Answer:
constipation and diarrhea, sodium loading leading to HTN or HF
exacerbation
Question:
PUD: cimetidine adverse effects
Answer:
antiandrogenic effects, CNS effects (hallucinations, confusion or
depression/excitation), pneumonia
Question:
PUD: cimetidine mechanism of action
Answer:
selectively blocks H2 receptors to decrease gastric acid secretion
