Midterm Test: NR565 / NR 565
(Latest Update )
Advanced Pharmacology
Fundamentals | Questions with
Answers | Grade A | 100% Correct –
Chamberlain
Question:
Aspirin Adverse effects (3)
Answer:
renal impairment
Reye syndrome in children <18 (encephalopathy and fatty liver)
salicylism (HA, tinnitus, dizziness)
Question:
Colchicine Indications
Answer:
Gout for patients unresponsive or intolerant to safer therapies
,Question:
Celecoxib adverse effects (2)
Answer:
increased risk for thrombotic events
GI issues (dyspepsia, abd pain, gastric ulcer)
Question:
Gout tx selection: Gout Attack
Answer:
1st line: NSAIDs
Glucocorticoids if NSAID ineffective or poorly tolerated
colchicine if unresponsive to NSAIDS and Glucocorticoids
Question:
Gout Tx selection: Management
Answer:
1st line allopurinol, followed by probenecid, with pegloticase last resort d/t
cost and adverse effects
,Question:
Probenecid Key Points (4)
Answer:
prolong effects of abx
hypersensitivity risk
renal injury from urate deposition in kidneys
can trigger gout attack in first months following initiation of therapy
Question:
Calcitonin MOA
Answer:
decrease plasma calcium by inhibiting resorption from bone and increasing
calcium excretion by kidneys
Question:
Calcium Salt contraindications (2)
Answer:
hx renal calculi
hypophosphatemia
, Question:
Vitamin D Deficiency effects (2)
Answer:
decrease calcium and phosphorus in intestine and decreased resorption from
bone
increased renal excretion of calcium and phosphate
Question:
Bisphosphonate Administration/Consideration
Answer:
sit upright 30min after taking d/t risk of esophagitis
Question:
Potentially inappropriate medications for pediatrics (2)
Answer:
fluoroquinolones (d/t tendon rupture)
OTC cold and cough medicine
(Latest Update )
Advanced Pharmacology
Fundamentals | Questions with
Answers | Grade A | 100% Correct –
Chamberlain
Question:
Aspirin Adverse effects (3)
Answer:
renal impairment
Reye syndrome in children <18 (encephalopathy and fatty liver)
salicylism (HA, tinnitus, dizziness)
Question:
Colchicine Indications
Answer:
Gout for patients unresponsive or intolerant to safer therapies
,Question:
Celecoxib adverse effects (2)
Answer:
increased risk for thrombotic events
GI issues (dyspepsia, abd pain, gastric ulcer)
Question:
Gout tx selection: Gout Attack
Answer:
1st line: NSAIDs
Glucocorticoids if NSAID ineffective or poorly tolerated
colchicine if unresponsive to NSAIDS and Glucocorticoids
Question:
Gout Tx selection: Management
Answer:
1st line allopurinol, followed by probenecid, with pegloticase last resort d/t
cost and adverse effects
,Question:
Probenecid Key Points (4)
Answer:
prolong effects of abx
hypersensitivity risk
renal injury from urate deposition in kidneys
can trigger gout attack in first months following initiation of therapy
Question:
Calcitonin MOA
Answer:
decrease plasma calcium by inhibiting resorption from bone and increasing
calcium excretion by kidneys
Question:
Calcium Salt contraindications (2)
Answer:
hx renal calculi
hypophosphatemia
, Question:
Vitamin D Deficiency effects (2)
Answer:
decrease calcium and phosphorus in intestine and decreased resorption from
bone
increased renal excretion of calcium and phosphate
Question:
Bisphosphonate Administration/Consideration
Answer:
sit upright 30min after taking d/t risk of esophagitis
Question:
Potentially inappropriate medications for pediatrics (2)
Answer:
fluoroquinolones (d/t tendon rupture)
OTC cold and cough medicine
