1
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NURS6630 ///NURS 6630
PSYCHOPHARMACOLOGY MIDTERM EXAM
2 VERSIONS ACTUAL MIDTERM EXAM
Questions and Answers (100% Correct
Answers) Already Graded A+
Serotonin regulates [ ANS: ] Mood, emotion, feeding, and
reproductive behavior
© 2025 Assignment Expert
This class of antidepressants binds to presynaptic SERT and inhibits
them from reuptake of serotonin to increase levels in the synaptic
cleft to bind with postsysnaptic 5HT2 receptors [ ANS: ] SSRIs
First line therapy for MDD due to milder side effect profiles [ ANS: ]
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SSRIs
Six Common SSRIs [ ANS: ] citalopram, escitalopram, fluoxetine,
fluvoxamine, sertraline, paroxetine
Onset of therapeutic benefit from SSRIs [ ANS: ] 4-6 weeks
In addition to MDD, SSRIs also treat [ ANS: ] Chronic Anxiety, PTSD,
OCD, and eating disorders (bulimia)
Five Common side effects of SSRIs include [ ANS: ] Anxiety,
insomnia, GI distress, sexual dysfunction (ED), SIADH
Severe side effect of SSRIs in children/adolescents under age 25
years old [ ANS: ] suicidal ideation
Life threatening adverse effect of SSRIs, especially when used in
combination with other serotonergic drugs (SNRIs, TCAs, MAOIs,
etc.) [ ANS: ] Serotonin Syndrome
Excess accumulation of serotonin resulting in overstimulation of the
nervous system [ ANS: ] Serotonin Syndrome
, 2
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Seven symptoms of Serotonin Syndrome [ ANS: ] Flushing,
hyperthermia, agitation, muscle rigidity, seizure, coma,
HYPERreflexia
The treatment for serotonin syndrome [ ANS: ] Cyproheptadine (5-
HT2 receptor antagonist)
Cyproheptadine treats serotonin syndrome by [ ANS: ] blocking 5-
HT2 receptors (serotonin antagonist)
When SSRIs or SNRIs are stopped abruptly, common symptoms of
withdrawal include [ ANS: ] Irritability, headaches, and insomnia
© 2025 Assignment Expert
Medicine specific side effect of citalopram [ ANS: ] Prolonged QT
interval (normal=0.4.-0.44 seconds)
This SSRI is pregnancy category D due to associations with
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congenital heart defects [ ANS: ] Paroxetine
All SSRIs but paroxetine (D) are pregnancy category [ ANS: ] C
Three SSRIs that are inhibitors of Cytochrome P450 enzymes [ ANS: ]
fluoxetine, fluvoxamine, and paroxetine
Five common SNRIs include [ ANS: ] duloxetine, venlafaxine,
desvenlafaxine, milnacipran, levomilnacipran
This antidepressant class of medications works by binding to
presynaptic SERT and NET to inhibit them from reuptake of
serotonin and norepinephrine to increase their levels in the
synaptic cleft [ ANS: ] SNRIs
In addition to MDD SNRIs treat [ ANS: ] Anxiety and neuropathic
pain (peripheral neuropathy)
Medication specific indications of duloxetine: [ ANS: ] urinary
incontinence and Fibromyalgia
Medication specific indications of venlafaxine: [ ANS: ] social
anxiety, panic disorders, PTSD, OCD, postmenopausal hot flashes
, 3
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Six common side effects of SNRIs include: [ ANS: ] Insomnia,
nausea, sexual dysfunction, hypertension, sweating, headaches
Severe side effect of SNRIs in children/adolescents under age 25
years old: [ ANS: ] suicidal ideation
Life threatening adverse effect of SNRIs, especially when used in
combination with other serotonergic drugs: [ ANS: ] Serotonin
Syndrome
This SNRI is an inhibitor of Cytochrome P450 enzymes: [ ANS: ]
venlafaxine
© 2025 Assignment Expert
This SNRI is hepatotoxic: [ ANS: ] duloxetine
MAOIs increase the levels of: [ ANS: ] Serotonin, Norepinephrine,
and Dopamine
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Norepinephrine regulates: [ ANS: ] alertness and focus
Dopamine regulates: [ ANS: ] cognitive function, motivation, and
awakeness
In the synaptic cleft, Monoamine Oxidase A breaks down: [ ANS: ]
Serotonin, Norepinephrine, and Dopamine
In the synaptic cleft, Monoamine Oxidase B breaks down: [ ANS: ]
Dopamine
MAOIs are especially effective in: [ ANS: ] Atypical depression
(mood responds to positive events and symptoms include
increased appetite, weight gain, sleepiness, and fatigue)
Non-selective MAOIs inhibit enzymes: [ ANS: ] MAO-A and MAO-B
Selective MAOIs only inhibit the enzyme: [ ANS: ] MAO-B
Three non-selective MAOIs: [ ANS: ] isocarboxazid, phenelzine,
tranylcypromine
For Expert help and assignment solutions, +254707240657
NURS6630 ///NURS 6630
PSYCHOPHARMACOLOGY MIDTERM EXAM
2 VERSIONS ACTUAL MIDTERM EXAM
Questions and Answers (100% Correct
Answers) Already Graded A+
Serotonin regulates [ ANS: ] Mood, emotion, feeding, and
reproductive behavior
© 2025 Assignment Expert
This class of antidepressants binds to presynaptic SERT and inhibits
them from reuptake of serotonin to increase levels in the synaptic
cleft to bind with postsysnaptic 5HT2 receptors [ ANS: ] SSRIs
First line therapy for MDD due to milder side effect profiles [ ANS: ]
Guru01 - Stuvia
SSRIs
Six Common SSRIs [ ANS: ] citalopram, escitalopram, fluoxetine,
fluvoxamine, sertraline, paroxetine
Onset of therapeutic benefit from SSRIs [ ANS: ] 4-6 weeks
In addition to MDD, SSRIs also treat [ ANS: ] Chronic Anxiety, PTSD,
OCD, and eating disorders (bulimia)
Five Common side effects of SSRIs include [ ANS: ] Anxiety,
insomnia, GI distress, sexual dysfunction (ED), SIADH
Severe side effect of SSRIs in children/adolescents under age 25
years old [ ANS: ] suicidal ideation
Life threatening adverse effect of SSRIs, especially when used in
combination with other serotonergic drugs (SNRIs, TCAs, MAOIs,
etc.) [ ANS: ] Serotonin Syndrome
Excess accumulation of serotonin resulting in overstimulation of the
nervous system [ ANS: ] Serotonin Syndrome
, 2
For Expert help and assignment solutions, +254707240657
Seven symptoms of Serotonin Syndrome [ ANS: ] Flushing,
hyperthermia, agitation, muscle rigidity, seizure, coma,
HYPERreflexia
The treatment for serotonin syndrome [ ANS: ] Cyproheptadine (5-
HT2 receptor antagonist)
Cyproheptadine treats serotonin syndrome by [ ANS: ] blocking 5-
HT2 receptors (serotonin antagonist)
When SSRIs or SNRIs are stopped abruptly, common symptoms of
withdrawal include [ ANS: ] Irritability, headaches, and insomnia
© 2025 Assignment Expert
Medicine specific side effect of citalopram [ ANS: ] Prolonged QT
interval (normal=0.4.-0.44 seconds)
This SSRI is pregnancy category D due to associations with
Guru01 - Stuvia
congenital heart defects [ ANS: ] Paroxetine
All SSRIs but paroxetine (D) are pregnancy category [ ANS: ] C
Three SSRIs that are inhibitors of Cytochrome P450 enzymes [ ANS: ]
fluoxetine, fluvoxamine, and paroxetine
Five common SNRIs include [ ANS: ] duloxetine, venlafaxine,
desvenlafaxine, milnacipran, levomilnacipran
This antidepressant class of medications works by binding to
presynaptic SERT and NET to inhibit them from reuptake of
serotonin and norepinephrine to increase their levels in the
synaptic cleft [ ANS: ] SNRIs
In addition to MDD SNRIs treat [ ANS: ] Anxiety and neuropathic
pain (peripheral neuropathy)
Medication specific indications of duloxetine: [ ANS: ] urinary
incontinence and Fibromyalgia
Medication specific indications of venlafaxine: [ ANS: ] social
anxiety, panic disorders, PTSD, OCD, postmenopausal hot flashes
, 3
For Expert help and assignment solutions, +254707240657
Six common side effects of SNRIs include: [ ANS: ] Insomnia,
nausea, sexual dysfunction, hypertension, sweating, headaches
Severe side effect of SNRIs in children/adolescents under age 25
years old: [ ANS: ] suicidal ideation
Life threatening adverse effect of SNRIs, especially when used in
combination with other serotonergic drugs: [ ANS: ] Serotonin
Syndrome
This SNRI is an inhibitor of Cytochrome P450 enzymes: [ ANS: ]
venlafaxine
© 2025 Assignment Expert
This SNRI is hepatotoxic: [ ANS: ] duloxetine
MAOIs increase the levels of: [ ANS: ] Serotonin, Norepinephrine,
and Dopamine
Guru01 - Stuvia
Norepinephrine regulates: [ ANS: ] alertness and focus
Dopamine regulates: [ ANS: ] cognitive function, motivation, and
awakeness
In the synaptic cleft, Monoamine Oxidase A breaks down: [ ANS: ]
Serotonin, Norepinephrine, and Dopamine
In the synaptic cleft, Monoamine Oxidase B breaks down: [ ANS: ]
Dopamine
MAOIs are especially effective in: [ ANS: ] Atypical depression
(mood responds to positive events and symptoms include
increased appetite, weight gain, sleepiness, and fatigue)
Non-selective MAOIs inhibit enzymes: [ ANS: ] MAO-A and MAO-B
Selective MAOIs only inhibit the enzyme: [ ANS: ] MAO-B
Three non-selective MAOIs: [ ANS: ] isocarboxazid, phenelzine,
tranylcypromine
