ONS CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATE LATEST UPDATE ACTUAL EXAM

ONS CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATE LATEST
UPDATE ACTUAL EXAM QUESTIONS
DefineLneoadjuvantLtherapyL-
LCORRECTLANSWERSTreatmentLisLgivenLpriorLtoLsurgeryLtoLshrinkLtheLtumor




DefineLadjuvantLtherapyL-
LCORRECTLANSWERSAdditionalLcancerLtreatmentLgivenLafterLtheLprimaryLtreatmentLtoLlowerLtheLri


skLthatLtheLcancerLreoccur



3LsubcategoriesLofLalkylatingLagents:L-LCORRECTLANSWERS1.LNitrogenLmustards

2.LPlatinum-
basedLagentsL(doLnotLpossessLanLalkylLgroupLbutLstillLtermedLalkylatingLagentsLasLtheyLworkLsimilarl
y)

3.LNitrosoureas



CommonLalkylatingLagents:L-LCORRECTLANSWERSCyclophosphamideL(Cytoxan)

IfosfamideL(Ifex)

BendamustineL(Treanda)



CommonLplatinum-basedLagents:L-LCORRECTLANSWERSCisplatinL(Platinol)

CarboplatinL(Paraplatin)



WhatLisLuniqueLaboutLnitrosoureasLagents?L-LCORRECTLANSWERSAbleLtoLcrossLtheLblood-
brainLbarrier;LcanLbeLeffectiveLinLtreatingLsomeLbrainLtumors



CommonLnitrosoureasLagents:L-LCORRECTLANSWERSCarmustineL(BiCNU)

LomustineL(CeeNu)

,StreptozocinL(Zanosar)



HypersensitivityLcanLoccurLwithLlateLdosesLof:L-LCORRECTLANSWERSCarboplatin



TheseLagentsLareLtypicallyLcategorizedLasLhighlyLemetogenic:L-
LCORRECTLANSWERS1.LAlkylatingLagents



2.LNitrosoureas



Pre-administrationLlabsLforLalkylatingLagentsLandLnitrosoureas:L-LCORRECTLANSWERSBUN

Creatinine

CBCLw/Ldiff



WhatLisLtheLmedicationLMesnaLusedLfor?L-
LCORRECTLANSWERSBladderLprotectantLwithLadministrationLofLcyclophosphamideLorLifosfamide




InstructLptsLreceivingL________LtoLavoidLexposureLtoLcoldLairLandLconsumingLcoldLfluidsLforL3-
4LdaysLfollowingLtreatmentL-LCORRECTLANSWERSOxaliplatin



HowLdoLantimetabolitesLfunction?L-
LCORRECTLANSWERSByLblockingLDNALandLRNALgrowthLbyLinterferingLwithLenzymesLneededLforLnor


malLcellLmetabolism



AntimetabolitesLworkLinLtheL___Lphase.L-LCORRECTLANSWERSS



CommonLsideLeffectsLofLantimetabolites:L-LCORRECTLANSWERSMyelosuppression

GILtoxicities

Photosensitivity

, Hand-footLsyndrome



CommonLantimetaboliteLdrugs:L-LCORRECTLANSWERSAzacitidine

Capecitabine

5-FU

Cytarabine

Decitabine

Methotrexate



TheLinstituteLforLSafeLMedicationLPracticesLrecommendsLwhatLrouteLofLadministrationLforLvincristi
ne?L-LCORRECTLANSWERSIVLpiggybackLviaLgravity



AnthracyclineLantitumorLabxLworkLby:L-
LCORRECTLANSWERSInterferingLwithLenzymesLnecessaryLforLDNALtoLreplicateLinLALLLphasesLofLtheL


cellLcycle



TheLtwoLmajorLclassificationsLofLantitumorLantibioticsLare:L-LCORRECTLANSWERSAnthracyclines

Non-anthracyclines



CommonLanthracyclineLantitumorLabx:L-LCORRECTLANSWERSDaunorubicin

Doxorubicin

Epirubicin

Idarubicin



TheLantitumorLabxL___________LisLnotLanLanthracycline,LbutLhasLanthracycline-typeLproperties.L-
LCORRECTLANSWERSMitoxantrone