ONS ONCC CHEMO RENEWAL EXAM QUESTIONS WITH CORRECT ANSWERS RATED A.pdfONS ONCC CHEMO RENEWAL EXAM QUESTIONS WITH CORRECT ANSWERS RATED A.pdf

ONS ONCC CHEMO RENEWAL EXAM QUESTIONS
WITH CORRECT ANSWERS RATED A+
NeoadjuvantVtherapyVdoesVnotVincreaseVsurvivalVwhenVcomparedVtoVadjuvantVtherapy.VItVonlyVch
angesVtheVtimingVofVtreatmentVandVcanVchangeVsurgicalVoptionsVifVtheVtumorVisVshrunkVenough.VIfV
thisVoccurs,VtheVpatientVmayVonlyVrequireVaVlumpectomyVplusVradiationVtherapyVinsteadVofVneedin
gVaVmastectomyV-
VCORRECTVANSWERSMainVbenefitVofVneoadjuvantVchemotherapyV(breastVcancerVpatient)




AVcomprehensiveVgeriatricVassessmentV(CGA)VisVaVmultidisciplinaryVevaluationVtoVassessVlifeVexpe
ctancyVandVriskVofVmorbidityVandVmortalityVinVtheVolderVpatient.VThisVassessmentVtoolVwouldVeval
uateVandVincludeVtheVfollowingVareas:VfunctionalVstatus,VsocioeconomicVissues,VpsychosocialVdistr
ess,Vcomorbidities,VcognitiveVfunction,VnutritionalVstatus,Vpolypharmacy,VandVaVmedicationVrevie
wV(NCCNVOlderVAdultVOncologyVGuidelines,VversionV1.2015).V-
VCORRECTVANSWERSDueVtoVMrs.VTurner'sVageVandVcomorbidities,VherVoncologistVperformsVaVcom


prehensiveVgeriatricVassessment.VYouVknowVthatVthisVassessmentVcoversVallVbutVwhichVofVtheVfollo
wing:



65V-
VCORRECTVANSWERSTheVNCCNVOlderVAdultVOncologyVGuidelinesV(versionV1.2015)VprovidesVinfor


mationVonVwhatVisVincludedVinVaVcomprehensiveVgeriatricVassessment.VCurrently,VmoreVthanV60%V
ofVcancersVinVtheVUnitedVStatesVoccurVinVpeopleVageV______andVolderVandVasVtheVoncologyVworldV
ages,VnearlyVhalfV(46%)VofVcancerVsurvivorsVareV70VyearsVofVageVorVolder



TwoVofVtheVagentsV(docetaxelVandVcarboplatin)VthatVMrs.VTurnerVwillVreceiveVareVcategorizedVasVirr
itants.VDocetaxelVcanVcauseVaVsignificantVreactionVifVitVextravasates.VItVcanVleadVtoVedema,Verythe
ma,VoccasionalVpainVandVblisterVformationV(ONSVChemo/BioVguidelines,V2014).VThatVisVtheVmostVli
kelyVreasonVthatVMrs.VTurnerVwasVgivenVaVportVforVherVtreatments.VSomeVpatientsVwillVreceiveVthe
irVtreatmentsVthroughVaVperipheralVIVVwithoutVincident.VJustVbecauseVtheyVareVintravenousVagent
sVdoesVnotVmeanVthatVaVportVisVrequiredVandVneedingVaVportVhasVnothingVtoVdoVwithVherVbeingVold
erVinVage.VSinceVnoneVofVtheseVagentsVareVvesicants,VtheyVlikelyVcouldVhaveVbeenVgivenVsafelyVviaV
peripheralVrouteVbutVhavingVaVportVplacedVisVOKVasVwell.V-
VCORRECTVANSWERSWhatVisVyourVbestVexplanationVforVwhyVMrs.VTurnerVwasVgivenVaVportVtoVrecei


veVherVchemotherapy?

,IrrirtantsV-
VCORRECTVANSWERS_____________can VcauseVinflammation,Vpain,VandVburningVbutVrarelyVcause


VtissueVnecrosisVcomparableVtoVaVvesicantV(unlessVaVlargeVamountVorVaVveryVhighVconcentrationVofV


theVirritantVisVextravasated).



VesicantsV-
VCORRECTVANSWERS_____________can VcauseVblisteringVandVsignificantVpainVandVtissueVdamageV


andVdestruction,VleadingVtoVtissueVdeath.



Non-DNA-
bindingVsolutionsVremainVinVtheVlocalVareaVofVtheVextravasation,VwhichVimprovesVtheVpossibilityVof
VdrugVdeactivation.



DNA-
bindingVagentsVattachVtoVDNAVnucleicVacids,VcausingVtheVantagonistVtoVbeVingestedVcellularly,Vlead
ingVtoVprogressiveVtissueVdestructionV-
VCORRECTVANSWERSAVfurtherVclassificationVofVanVantineoplasticVagent'sVpotentialVtoVcauseVdama


geVisVwhetherVitsVmechanismVofVactionVincludesVDNAVbinding.



Bendamustinea

Dactinomycin

Daunorubicin

Doxorubicin

Epirubicin

Idarubicin

Mechlorethamine

MitomycinV-VCORRECTVANSWERSDNAVBindingVIrritants



Amsacrine

, Paclitaxel

Vinblastine

Vincristine

Vindesine

VinorelbineV-VCORRECTVANSWERSDNAVNonbindingVvessicants



SodiumVthiosulfate



InjectV2VmlVofVsodiumVthiosulfateVforVeachVmilligramVof

mechlorethamineVextravasated.

InjectVsubcutaneouslyVintoVextravasationVsiteVusingVaV25

gaugeVorVsmallerVneedleV(changeVneedleVwithVeachVinjection).

MonitorVextravasationVsiteVaccordingVtoVtheVinstitution's

policiesVandVprocedures.V-VCORRECTVANSWERSExtravasciationVAlkylatingV/VMechlorethamineVtx



ApplyVwarmVcompresses.V

Dexamethasone

8VmgVtwiceVdaily

forV14VdaysV-VCORRECTVANSWERSExtravasciationVAlkylating:VOxaliplatin



Totect



ApplyViceVpackV(removeV15

minutesVpriorVtoVTotect

treatment).