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□ State the three (3) most important characteris cs of any drug. - Ans think of the drugs'
"succESS":
E_ffec veness
S_afety
S_elec vity.
□ Is it possible to have a selec ve drug? - Ans No. All medica ons have side effects.
□ Define the four phases of pharmacokine cs. - Ans Absorp on, distribu on, metabolism, and
excre on.
Think: "ADME"
A_bsorp on
D_istribu on
M_etabolism
E_xcre on
□ Define pharmacodynamics. - Ans The nature and intensity of the response that the drug has
on the body.
"pharmaco-do-to-my-body-namics"
,□ Which member of the health care team is most likely to observe and evaluate drug responses
and intervene if required? - Ans The nurse
□ Name the three most important goals of pre-administra on assessment. - Ans a) Evaluate
effects
b) iden fy high-risk pa ents
c) assess for self care
□ What factors can predispose an individual to adverse reac ons from drugs? - Ans a) Allergies
b) pregnancy
c) age
d) gene cs
e) pathological disease (kidney or liver)
□ What measures help reduce adverse reac ons of medica on administra on? - Ans Think:
H&H
History - get a thorough pa ent history
High-risk & educa on - iden fy those with risk factors
□ What type of research is required to assess drug therapies? - Ans The randomized controlled
trial is required for all new medica ons.
□ What is a "blinded" study? - Ans Par cipants don't know if they belong to the control or
experimental group.
,□ Which Amendment strengthened drug regula on a6er the Thalidomide tragedy in Europe? -
Ans The Harris-Kefauver Amendment to the FDA and the Cosme c Act of 1962.
□ What is the purpose of having a trade name (proprietary or brand name) for a drug? - Ans
Trade names are easy to recall and pronounce and good for marke ng purposes.
□ What is one of the problems with trade names? - Ans Using 2 brand named drugs that have
the same ingredient can lead to overdose.
□ What are some limita ons in the tes ng process used to bring drugs to market? - Ans
Informa on on women and children is limited.
□ What is another limita on in the tes ng process used to bring drugs to market? - Ans New
drugs are likely to have adverse effects not detected in clinical trials
□ What is the cost to develop a new drug in the U.S.? - Ans It can exceed $800 million dollars.
□ When wri ng the names of drugs generic names are not capitalized and brand name
are____________? - Ans Capitalized
□ Which scheduled drugs can NPs prescribe in the state of Florida? - Ans Since 2017 NPs have
prescrip ve authority for controlled substances
□ Give an example of Schedule II drugs. - Ans Codeine, fentanyl, hydromorphone, morphine,
dextroamphetamine.
□ Give examples of Schedule III drugs. - Ans Narco cs:
Vicodin
, Codeine
Suboxone (buprenorphine)
Others:
Didrex (benzemphetamine)
Ketamine
A-Phedrin (psuedoepherine)
Abilify (aripiprazole)
Accupril (quinapril)
Accutane (isotre noin)
Tylenol PM (acetamynophen with diphenhydramine)
anabolic steroids.
Pepcid (famo dine)
□ Give an example of a Schedule IV drugs. - Ans Benodiazepines: CNS effect, open GABA-a
channels
examples:
Tramadol (Ultram)
Xanax (alprazolam)
Valium (diazepam)
Klonopin (clonazepam)
A van (Lorazepam)
□ Benzodiazepines are Schedule_________ drugs? - Ans Schedule IV drugs.