n
, Table of contents n n
Chapter 1 - Cellular Biology ____________________________________________________________ 3
n n n n
Chapter 2 - Altered Cellular and Tissue Biology Environmental Agents
n n n n n n n n n 16 Chapter 3 - The Cellular
n n n n n n
nEnvironment Fluids and Electrolytes Acids and n n n n n
Bases ______________________________________________________________________________ 28
Chapter 4 - Genes and Genetic Diseases ___________________________________________________ 41
n n n n n n
Chapter 5 - Genes Environment-Lifestyle and Common Diseases ________________________________ 51
n n n n n n n
Chapter 6 - Epigenetics and Disease _______________________________________________________ 59
n n n n n
Chapter 7 - Innate Immunity Inflammation ___________________________________________________ 64
n n n n n
Chapter 8 - Adaptive Immunity ____________________________________________________________ 78
n n n n
Chapter 9 - Alterations in Immunity and Inflammation ________________________________________ 89
n n n n n n n
Chapter 10 - Infection _________________________________________________________________ 102
n n n
Chapter 11 - Stress and Disease ________________________________________________________ 110
n n n n n
Chapter 12 - Cancer Biology ___________________________________________________________ 117
n n n n
Chapter 13 - Cancer Epidemiology ______________________________________________________ 129
n n n n
Chapter 14 - Cancer in Children _________________________________________________________ 135
n n n n n
Chapter 15 - Structure and Function of the Neurologic System _________________________________ 140
n n n n n n n n n
Chapter 16 - Pain Temperature Regulation Sleep and Sensory Function 151 Chapter 17 - Alterations in
n n n n n n n n n n n n n n n
nCognitive Systems Cerebral Hemodynamics and
n n n n
Motor Function ______________________________________________________________________ 165
n
Chapter 18 - Disorders of the Central and Peripheral Nervous Systems and
n n n n n n n n n n n
the Neuromuscular Junction ___________________________________________________________ 179
n n
Chapter 19 - Neurobiology of Schizophrenia Mood Disorders and Anxiety Disorders
n n n n n n n n n n 189
Chapter 20 - Alterations of Neurologic Function in Children ___________________________________ 195
n n n n n n n n
Chapter 21 - Mechanisms of Hormonal Regulation
n n n n n n n n n n n n n n n n n n n n n n n n n n n n n
n n n n 202 Chapter 22 - Alterations of Hormonal Regulation __________________________________ 211
n n n n n n n
Chapter 23 - Obesity and Disorders of Nutrition NEW ________________________________________ 223
n n n n n n n n
Chapter 24 - Structure and Function of the Reproductive Systems ______________________________ 228
n n n n n n n n n
Chapter 25 - Alterations of the Female Reproductive System __________________________________ 237
n n n n n n n n
Chapter 26 - Alterations of the Male Reproductive System_____________________________________ 246
n n n n n n n n
https://www.stuvia.com/user/angelinas
,Chapter 27 - Sexually Transmitted Infections ____________________________ 252
n n n n n
Chapter 28 - Structure and Function of the Hematologic System ______________ 260
n n n n n n n n n
Chapter 29 - Alterations of Erythrocyte Platelet and Hemostatic Function _______ 270
n n n n n n n n n
Chapter 30 - Alterations of Leukocyte and Lymphoid Function _______________ 280
n n n n n n n n
Chapter 31 - Alterations of Hematologic Function in Children ________________ 287
n n n n n n n n
Chapter 32 - Structure and Function of the Cardiovascular and Lymphatic Systems
n n n n n n n n n n n
______________________________________________________________ 297
Chapter 33 - Alterations of Cardiovascular Function _______________________ 309
n n n n n n
Chapter 34 - Alterations of Cardiovascular Function in Children ______________ 323
n n n n n n n n
Chapter 35 - Structure and Function of the Pulmonary System _______________ 331
n n n n n n n n n
Chapter 36 - Alterations of Pulmonary Function __________________________ 341
n n n n n n
Chapter 37 - Alterations of Pulmonary Function in Children _________________ 357
n n n n n n n n
Chapter 38 - Structure and Function of the Renal and Urologic Systems ________ 365
n n n n n n n n n n n
Chapter 39 - Alterations of Renal and Urinary Function _____________________ 375
n n n n n n n n
Chapter 40 - Alterations of Renal and Urinary Tract Function in Children ________ 385
n n n n n n n n n n n
Chapter 41 - Structure and Function of the Digestive System ________________ 393
n n n n n n n n n
Chapter 42 - Alterations of Digestive Function ___________________________ 404
n n n n n n
Chapter 43 - Alterations of Digestive Function in Children ___________________ 415
n n n n n n n n
Chapter 44 - Structure and Function of the Musculoskeletal System ___________ 424
n n n n n n n n n
Chapter 45 - Alterations of Musculoskeletal Function ______________________ 436
n n n n n n
Chapter 46 - Alterations of Musculoskeletal Function in Children _____________ 448
n n n n n n n n
Chapter 47 - Structure Function and Disorders of the Integument _____________ 457
n n n n n n n n n
Chapter 48 - Alterations of the Integument in Children ______________________ 468
n n n n n n n n
Chapter 49 - Shock Multiple Organ Dysfunction Syndrome and Burns in
n n n n n n n n n n
Adults _________________________________________________________ 476
Chapter 50 - Shock Multiple Organ Dysfunction Syndrome and Burns in
n n n n n n n n n n
Children ________________________________________________________ 483
, Chapter 01: Cellular Biology
n n n
MULTIPLE CHOICE n
1. Which statement best describes the cellular function of metabolic absorption?
n n n n n n n n n
a. Cells can produce proteins. n n n
b. Cells can secrete digestive enzymes. n n n n
c. Cells can take in and use nutrients. n n n n n n
d. Cells can synthesize fats. n n n
ANS: C n
In metabolic absorption, all cells take in and use nutrients and other substances from their
n n n n n n n n n n n n n n
surroundings. The remaining options are not inclusive in their descriptions of cellular
n n n n n n n n n n n n
metabolic absorption.
n n
PTS: n n 1 DIF: Cognitive Level: Remembering n n
2. Where is most of a cell’s genetic information, including RNA and DNA, contained?
n n n n n n n n n n n n
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS: C n
The nucleus contains the nucleolus, a small dense structure composed largely of RNA, most of the
n n n n n n n n n n n n n n n
cellular DNA, and the DNA-binding proteins, such as the histones, which regulate its activity.
n n n n n n n n n n n n n n
The mitochondria are responsible for cellular respiration and energy production.
n n n n n n n n n n
Ribosomes’ chief function is to provide sites for cellular protein synthesis. Lysosomes function
n n n n n n n n n n n n
as the intracellular digestive system.
n n n n n
PTS: n n 1 DIF: Cognitive Level: Remembering n n
3. Which component of the cell produces hydrogen peroxide (H2O2) by using oxygen to remove
n n n n n n n n n n n n n
n hydrogen atoms from specific substrates in an oxidative reaction?
n n n n n n n n
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS: B n
https://www.stuvia.com/user/angelinas