NAPLEX 2025/2026 Complete
Questions And Correct Answers
(Verified Answers)|Brand New
Version Grade A+!
T or F. Beyond use date must be applied to each compounded product using
USP 795 guidelines for Nonaqueous Liquids and Solid formulation and for Water-
containing Formulations. Correct Answer: True
Which of the following is considered with Non-Sterile Preparation? A. USP 795 B.
USP 797 Correct Answer: A
Labels on Pharmacy-compounded products - Expiration Dates (Beyond Use
Dates) Correct Answer: Water containing oral formulations
> The beyond use date is no later than 14 days when stored at controlled cold
temperature
Water containing topical/dermal/mucosal liquid and semisolid formulations
> The beyond use date is no later than 30 days
Nonaqueous formulations
> The beyond use date is no later than the time remaining until the earliest
expiration date of any API (use no later than 25% of time of this api) or 6 months,
whichever is earlier
T or F. For capsules, the label must include mcg or mg/capsule? Correct Answer:
True - Does not require for tablet
,T or F. You can rinse compounding equipment with tap water? Correct Answer:
False - you can only rinse Purified water for rinsing equipment
What is the best certified sterile compounding environment for injectable
product? Which ISO? Correct Answer: ISO class 5 (class 100) laminar air flow
hood within ISO class 7 (class 10,000) clean room with positive air pressure
differential relative to adjacent areas.
ISO class 5 (class 100) clean room with positive air pressure differential relative to
adjacent areas or a barrier isolator that provides a ISO class 5 (class 100)
environment for compounding
T or F. Liquids in a container curve up, therefore measure at the top of the
meniscus. Correct Answer: False. Must measure at the bottom of meniscus
What is the difference between glass and Wedge-wood/Porcelain(ceramic)
Mortar and Pestle? Correct Answer: wedge-wood or porcelain is used
commonly and is best for reducing particle size of dry powders and crystals
Glass is used for liquids or chemical that are oily or that will stain to the porcelain
T or F. It is safe not to use ointment paper to prepare creams and lotions
because these two formulation have the highest content of water. Water
content will cause the paper to moisten, and possibly tear. Correct Answer:
True. we can use Glassine weighing paper
Which of the following levigating agents are the best to prepare aqueous
systems (O/W dispersions)?
A. Glycerin B. Mineral oil C. Castor oil D. Cottonseed oil E. Tween 80 Correct
Answer: A. Glycerin
> Rest are good levigating agents used to prepare oleaginous systems (W/O)
,> Additional agents used as levigating agents to prepare aqueous systems
consist of Propylene glycol, polyethylene glycol 80
Sometimes heat is used to mix things easier, but it lead to over-heating which
produce undesired chemical-reactions. What is the best way to prevent over-
heating? Correct Answer: A water bath will help prevent over-heating
Fill in the blank
........................ refer to a compound prepared without a specific formula (not
from an official compendium) and made specifically to fill the needs of an
individual patient Correct Answer: Extemporaneous
Fill in the blank
...................... a single agent that is used to soften and smooth the skin. A
moisturizer is sometimes referred to as ................, but the term ............ is used for
single agent, and moisturizers often have coloring, scents, and other ingredients
added Correct Answer: Emollients
Fill in the blank
Oil in water , or water in Oil is example of ....... Correct Answer: Emulsions
Fill in the blank
............ Is used to stabilize the emulsion. ........... are usually surfactants (wetting
agents) that reduce the surface tension between the two liquids so that the two
different substances can move close to each other but they will not be mixed
together Correct Answer: Emulsifiers
What is the difference between Continental or dry gum method and English, or
wet gum method? Correct Answer: Both have same ingredients (oil, purified
, water and gum (such as acacia) in the ratio of 4:2:1 but the order of mixing is
different.
Dry method: gum is mixed rapidly with oil then water added all at once
Wet method: gum is dissolved in water first, then oil is slowly added
What you know about HLB (hydrophilic-Lipophilic balance) number? Correct
Answer: #s range from 0-20 with 10 being the mid-point means it is the break
point between water and oil solubility. #>10 means hydrophilic (water-soluble)
and #<10 means lipophilic (lipid-soluble)
What is Eutectic Mixture? Correct Answer: A eutectic mixture is two or more
components that melt at a temperature lower than the melting temperature for
the individual components.
Which of the following are common preservatives?
A. Benzalkonium chloride (BAK)
B. Benzyl alcohol
C. Chlorhexidine
D. Thimerosal (contain mercury)
E. Sodium benzoate
F. Benzethonium chloride
G. propylparaben Correct Answer: All of them
Why preservative-free formulations if there is no harm from multi-dose vials?
Correct Answer: no scientifically conclusive evidence exists of harm from
Questions And Correct Answers
(Verified Answers)|Brand New
Version Grade A+!
T or F. Beyond use date must be applied to each compounded product using
USP 795 guidelines for Nonaqueous Liquids and Solid formulation and for Water-
containing Formulations. Correct Answer: True
Which of the following is considered with Non-Sterile Preparation? A. USP 795 B.
USP 797 Correct Answer: A
Labels on Pharmacy-compounded products - Expiration Dates (Beyond Use
Dates) Correct Answer: Water containing oral formulations
> The beyond use date is no later than 14 days when stored at controlled cold
temperature
Water containing topical/dermal/mucosal liquid and semisolid formulations
> The beyond use date is no later than 30 days
Nonaqueous formulations
> The beyond use date is no later than the time remaining until the earliest
expiration date of any API (use no later than 25% of time of this api) or 6 months,
whichever is earlier
T or F. For capsules, the label must include mcg or mg/capsule? Correct Answer:
True - Does not require for tablet
,T or F. You can rinse compounding equipment with tap water? Correct Answer:
False - you can only rinse Purified water for rinsing equipment
What is the best certified sterile compounding environment for injectable
product? Which ISO? Correct Answer: ISO class 5 (class 100) laminar air flow
hood within ISO class 7 (class 10,000) clean room with positive air pressure
differential relative to adjacent areas.
ISO class 5 (class 100) clean room with positive air pressure differential relative to
adjacent areas or a barrier isolator that provides a ISO class 5 (class 100)
environment for compounding
T or F. Liquids in a container curve up, therefore measure at the top of the
meniscus. Correct Answer: False. Must measure at the bottom of meniscus
What is the difference between glass and Wedge-wood/Porcelain(ceramic)
Mortar and Pestle? Correct Answer: wedge-wood or porcelain is used
commonly and is best for reducing particle size of dry powders and crystals
Glass is used for liquids or chemical that are oily or that will stain to the porcelain
T or F. It is safe not to use ointment paper to prepare creams and lotions
because these two formulation have the highest content of water. Water
content will cause the paper to moisten, and possibly tear. Correct Answer:
True. we can use Glassine weighing paper
Which of the following levigating agents are the best to prepare aqueous
systems (O/W dispersions)?
A. Glycerin B. Mineral oil C. Castor oil D. Cottonseed oil E. Tween 80 Correct
Answer: A. Glycerin
> Rest are good levigating agents used to prepare oleaginous systems (W/O)
,> Additional agents used as levigating agents to prepare aqueous systems
consist of Propylene glycol, polyethylene glycol 80
Sometimes heat is used to mix things easier, but it lead to over-heating which
produce undesired chemical-reactions. What is the best way to prevent over-
heating? Correct Answer: A water bath will help prevent over-heating
Fill in the blank
........................ refer to a compound prepared without a specific formula (not
from an official compendium) and made specifically to fill the needs of an
individual patient Correct Answer: Extemporaneous
Fill in the blank
...................... a single agent that is used to soften and smooth the skin. A
moisturizer is sometimes referred to as ................, but the term ............ is used for
single agent, and moisturizers often have coloring, scents, and other ingredients
added Correct Answer: Emollients
Fill in the blank
Oil in water , or water in Oil is example of ....... Correct Answer: Emulsions
Fill in the blank
............ Is used to stabilize the emulsion. ........... are usually surfactants (wetting
agents) that reduce the surface tension between the two liquids so that the two
different substances can move close to each other but they will not be mixed
together Correct Answer: Emulsifiers
What is the difference between Continental or dry gum method and English, or
wet gum method? Correct Answer: Both have same ingredients (oil, purified
, water and gum (such as acacia) in the ratio of 4:2:1 but the order of mixing is
different.
Dry method: gum is mixed rapidly with oil then water added all at once
Wet method: gum is dissolved in water first, then oil is slowly added
What you know about HLB (hydrophilic-Lipophilic balance) number? Correct
Answer: #s range from 0-20 with 10 being the mid-point means it is the break
point between water and oil solubility. #>10 means hydrophilic (water-soluble)
and #<10 means lipophilic (lipid-soluble)
What is Eutectic Mixture? Correct Answer: A eutectic mixture is two or more
components that melt at a temperature lower than the melting temperature for
the individual components.
Which of the following are common preservatives?
A. Benzalkonium chloride (BAK)
B. Benzyl alcohol
C. Chlorhexidine
D. Thimerosal (contain mercury)
E. Sodium benzoate
F. Benzethonium chloride
G. propylparaben Correct Answer: All of them
Why preservative-free formulations if there is no harm from multi-dose vials?
Correct Answer: no scientifically conclusive evidence exists of harm from
