NAPLEX 2023 2025/2026 Complete
Questions And Correct Answers
(Verified Answers)|Brand New
Version Grade A+!
Key drugs that can cause hypothyroidism Correct Answer: "I TALC"
Interferons
Tyrosine Kinase Inhibitors
Amiodarone
Lithium
Carbamazepine
Conditions: Hashimoto's disease
Levothyroxine IV:PO Correct Answer: 0.75:1 (IV:PO)
Full replacement dose levothyroxine Correct Answer: 1.6 mcg/kg/day (IBW)
If known CAD: start with 12.5-25 mcg daily
Levothyroxine tablet colors Correct Answer: Orangutans Will Vomit On You Right
Before They Become Large Proud Giants
25 Orange
,50 White (no dye)
75 Violet
88 Olive
100 Yellow
112 Rose
125 Brown
137 Turquoise
150 Blue
175 Lilac
200 Pink
300 Green
Drug induced causes of hyperthyroidism Correct Answer: Iodine
Amiodarone
Interferons
Radiographic contrast media
treatment for thyroid storm Correct Answer: Antithyroid (PTU preferred- give 1
hour before iodide)
Inorganic iodide therapy (SSKI or Lugol's)
,Beta Blocker (Propranolol)
Systemic steroid (dexamethasone)
Aggressive cooling (APAP, cooling blankets, supportive treatments)
Hyperthyroid in pregnancy Correct Answer: Hyperthyroidism during pregnancy
should be treated with propylthiouracil (PTU) during the first trimester then
methimazole during the second and third trimesters. Although methimazole is a
teratogen, the teratogenic effects are less during the second and third
trimesters, and PTU can cause liver failure, which is why it is substituted out.
Cushing's syndrome Correct Answer: Adrenal gland produces too much cortisol
or exogenous steroids are taken in doses higher than normal amounts of
endogenous cortisol
Addison's disease Correct Answer: a condition that occurs when the adrenal
glands do not produce enough cortisol; Addisonian crisis (volume depletion and
hypotension, which can be fatal)
Steroids: least to most potent Correct Answer: (Cute Hot Pharmacists and
Physicians Marry Together & Deliver Babies)
o Cortisone (25 mg): short acting
o Hydrocortisone (20 mg): short acting
o Prednisone (5 mg): intermediate acting
o Prednisolone (5 mg): intermediate acting
o Methylprednisolone (4 mg): intermediate acting
o Triamcinolone (4 mg): intermediate acting
, o Dexamethasone (0.75 mg): long acting, highest potency
o Betamethasone (0.6 mg): long acting, highest potency
Immunosuppression from steroids Correct Answer: A patient is
immunosuppressed when using >/= 2mg/kg/day or >/= 20mg/day of prednisone
or prednisone equivalent for >2 weeks
Immunosuppressed patients cannot receive live vaccines and have a high risk
of infection
steroid will need to be slowly tapered off: reduce 10-20% every few days (tapers
can last 7-14 days, longer or shorter)
Traditional DMARDs (disease modifying anti-rheumatic drugs) Correct Answer:
MTX (Trexall): first line in RA
Hydroxychloroquine (Plaquenil)
Sulfasalazine
Leflunomide (Arava)
Traditional DMARDs (disease modifying anti-rheumatic drugs): MTX Correct
Answer: MTX (Trexall): first line in RA
- irreversibly binds and inhibit dihydrofolate reductase, inhibiting folate
- 7.5 to 20 mg once weekly
Questions And Correct Answers
(Verified Answers)|Brand New
Version Grade A+!
Key drugs that can cause hypothyroidism Correct Answer: "I TALC"
Interferons
Tyrosine Kinase Inhibitors
Amiodarone
Lithium
Carbamazepine
Conditions: Hashimoto's disease
Levothyroxine IV:PO Correct Answer: 0.75:1 (IV:PO)
Full replacement dose levothyroxine Correct Answer: 1.6 mcg/kg/day (IBW)
If known CAD: start with 12.5-25 mcg daily
Levothyroxine tablet colors Correct Answer: Orangutans Will Vomit On You Right
Before They Become Large Proud Giants
25 Orange
,50 White (no dye)
75 Violet
88 Olive
100 Yellow
112 Rose
125 Brown
137 Turquoise
150 Blue
175 Lilac
200 Pink
300 Green
Drug induced causes of hyperthyroidism Correct Answer: Iodine
Amiodarone
Interferons
Radiographic contrast media
treatment for thyroid storm Correct Answer: Antithyroid (PTU preferred- give 1
hour before iodide)
Inorganic iodide therapy (SSKI or Lugol's)
,Beta Blocker (Propranolol)
Systemic steroid (dexamethasone)
Aggressive cooling (APAP, cooling blankets, supportive treatments)
Hyperthyroid in pregnancy Correct Answer: Hyperthyroidism during pregnancy
should be treated with propylthiouracil (PTU) during the first trimester then
methimazole during the second and third trimesters. Although methimazole is a
teratogen, the teratogenic effects are less during the second and third
trimesters, and PTU can cause liver failure, which is why it is substituted out.
Cushing's syndrome Correct Answer: Adrenal gland produces too much cortisol
or exogenous steroids are taken in doses higher than normal amounts of
endogenous cortisol
Addison's disease Correct Answer: a condition that occurs when the adrenal
glands do not produce enough cortisol; Addisonian crisis (volume depletion and
hypotension, which can be fatal)
Steroids: least to most potent Correct Answer: (Cute Hot Pharmacists and
Physicians Marry Together & Deliver Babies)
o Cortisone (25 mg): short acting
o Hydrocortisone (20 mg): short acting
o Prednisone (5 mg): intermediate acting
o Prednisolone (5 mg): intermediate acting
o Methylprednisolone (4 mg): intermediate acting
o Triamcinolone (4 mg): intermediate acting
, o Dexamethasone (0.75 mg): long acting, highest potency
o Betamethasone (0.6 mg): long acting, highest potency
Immunosuppression from steroids Correct Answer: A patient is
immunosuppressed when using >/= 2mg/kg/day or >/= 20mg/day of prednisone
or prednisone equivalent for >2 weeks
Immunosuppressed patients cannot receive live vaccines and have a high risk
of infection
steroid will need to be slowly tapered off: reduce 10-20% every few days (tapers
can last 7-14 days, longer or shorter)
Traditional DMARDs (disease modifying anti-rheumatic drugs) Correct Answer:
MTX (Trexall): first line in RA
Hydroxychloroquine (Plaquenil)
Sulfasalazine
Leflunomide (Arava)
Traditional DMARDs (disease modifying anti-rheumatic drugs): MTX Correct
Answer: MTX (Trexall): first line in RA
- irreversibly binds and inhibit dihydrofolate reductase, inhibiting folate
- 7.5 to 20 mg once weekly
