DETAILED VERIFIED AND 100% ACCURATE ANSWERS
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Eosinophilic Granulomatosis Polyangitis (Churg-Strauss) diagnostic
criteria Ans✓✓✓4 of:
asthma
eosinophilia
mono or poly neuropathy,
paranasal sinus abnormality,
non-fixed pulmonary infiltrates on CXR
biopsy showing extravascular eosinophils
Praxbind (idarucizumab) Ans✓✓✓For the reversal of the anticoagulant
effects of dabigatran
Teicoplanin Ans✓✓✓Inhibits bacterial cell wall formation
Glomerulonephritis + low serum complement levels Ans✓✓✓post-
streptococcal glomerulonephritis
subacute bacterial endocarditis
systemic lupus erythematosus
mesangiocapillary glomerulonephritis
,Heinz bodies Ans✓✓✓G6PD deficiency, denatured haemoglobin within
red cells
Phaeochromocytoma mx Ans✓✓✓phenoxybenzamine - alpha blocker
then
beta-blockers
brudaga syndrome Ans✓✓✓SCN5A gene
ECG changes more apparent with Na channel blocker
Jervell and Lange-Nielsen syndrome Ans✓✓✓Profound deafness and a
prolonged QT interval
Discuss (4)Improve
Go Find Rex, Make Good Sex Ans✓✓✓
Thin Basement Membrane Disease Ans✓✓✓familial. adult. microscopic
hematuria without proteinuria. type 4 collagen. benign
Thrombotic Thrombocytopenic Purpura (TTP) Ans✓✓✓ADAMSTS13
deficiency or autoantibody, Normal PT/PTT
Can't cleave vWF into monomers, Microthrombi creating schistocytes
Pentad of neurolgical symptoms, thrombocytopaenia, haemoltyic
anaemia, fever and renal impairment
,Warm autoimmune hemolytic anemia Ans✓✓✓IgG antibodies react
with erythrocytes at normal body temperature. Extravascular.
Seen in CLL
aschof bodies Ans✓✓✓seen in rheumatic fever
Membraneous Glomerulonephritis Ans✓✓✓Cause of nephrotic
syndrome (not nephritic)
IgG and C3 deposition
a/w - malignancy (colon), penicillamines, heavy metals, RA, SLE, Hep
B, HIV, shisto, sickle
philidelphia chromosome Ans✓✓✓Translocation of a gene segment of
chromosomes 9&22.
Poor prognosis in ALL
CML
Burkitt's lymphoma Ans✓✓✓8:14 translocation; associated with EBV
causes growths on jaw
starry sky appearance'
*8 looks like a B*
, JVP waveform Ans✓✓✓a- *a*tria contract
c- tri*c*uspid closes
x- atria rela*x*es causing drop in pressures
v- atrial *V*illing
y- tr*y*cuspid opens
Primary hyperparathyroidism Ans✓✓✓mostly caused by parathyroid
adenoma
mx - parathyroidectomy, medical - cincicet (if pt >50 and calcium <0.25
upper limit, and no end-organ damage + stones)
a/w MEN I+II
Dengue Ans✓✓✓fever, rash, and retrorbital headache. Positive
*Herman's* sign (skin flushing) + thrombocytopaenia.
symptomatic mx
incubation 5-8 days
t14:18 Ans✓✓✓Follicular lymphoma
MEN 1 Ans✓✓✓3Ps
*Parathyroid*, pancreatic tumor (insulinoma), pituitary tumor
also adrenal and thyroid
MEN1 gene