Questions A+ GUARANTEED OVER 300 QUESTIONS AND
ANSWERS
What has to largest first pass effect in its oral form?
nitroglycerin Estrogen
-tx for DUB
-contraindication: thromboembolism
-s/s: nausea
-promotes osteoblast activity within bones
Progestin
-derivative of testosterone
-s/e: acne
-changes quantity and viscosity of cervical mucus
Clomiphene citrate stimulates ovulation BTB
(break through bleeding) occurs with combined
oral contraceptives Human menopausal
gonadotropin promotes ovulation FSH
initiates activity in the ovary
Finasteride
-treats BPH
-inhibits testosterone conversion Androgen
abuse is most common in athletic teams
What do anabolic steroids increase?
protein synthesis within cells --> cellular tissue buildup
What might androgens cause?
gynecomastia and priapism What
class is testosterone? schedule III
Tadalafil contraindication nitroglycerin
What medications should you avoid concomitant therapy with tadalafil?
verapamil, fluconazole, thioridazine, isosorbide mononitrate
,What drugs are unaffected by food intake (Men's health)? avanafil,
tadalafil
What hormones are produced by the anterior pituitary gland?
GH, TSH, ACTH
What does somatostatin inhibit the release of?
GH
Bromocriptine is the treatment for
prolactin secreting tumors S/S of graves
disease palpitations, nervousness, heat
intolerance
What medication should patients with sickle cell crisis avoid? demerol
(can cause seizure)
What do CCB do?
lower blood pressure (i.e. Cardizem)
What do corticosteroids increase?
blood sugar
What is the drug choice for hypothyroidism?
levothyroxine S/E
of Cosyntropin
edema
Glucocorticoids
-take acetaminophen for pain -influence
carb fat and protein metabolism
What medications cause gastric distress?
aspirin, ibuprofen, naproxen sodium, glucocorticoids What
should you assess before beginning steroid therapy?
uncontrolled DM
What may cause tinnitus and vertigo? aspirin
What is for an acetaminophen overdose?
,acetylcysteine
What herbal remedies increase sedation with opioids?
kava, valerian, st. john's wort
What do you monitor with acetaminophen therapy?
bilirubin, ALP, ALT
What might opioids cause? constipation
and respiratory depression Opioid
contraindication status asthmaticus
Superficial pain
skin and mucous membranes Deep
pain below skin level in tissues
Somatic pain skeletal muscle,
ligaments, and joints Visceral pain
organs and smooth muscles Adjuvant analgesic medications corticosteroids,
anticonvulsants, antidepressants, antidysrhythmic, local anesthetics
What is used in treatment for alcoholism?
psychosocial methods and naltrexone hydrochloride
Nalbuphine
-contraindication: head injuries
-depresses respirations --> CO2 retention and increased ICP
Salicylate toxicity s/s vertigo, tinnitus, hyperventilation
What NSAID can cause Reye syndrome in children with viral illnesses?
aspirin S/E of Celecoxib
sinusitis, dizziness, headache
What is Celecoxib used for?
osteoarthritis, rheumatoid arthritis, acute pain symptoms
Anti-inflammatories inhibit
prostaglandin 2nd gen NSAIDs
, selective cyclooxygenase-2 inhibitors
Gout
metabolic disorder of uric acid and purines that attack joints and tendons
Ketorolac tromethamine
NSAID administered IV or orally for short-term pain What
is Colchicine used for?
gout - inhibits migration of leukocytes to inflamed site Allopurinol
reduces uric acid synthesis for
gout
Methotrexate immunosuppressive, tx for
rheumatoid arthritis Monoamine oxidase
enzyme inhibited by antiparkinson drug selegiline What
neurotransmitters are out of balance in Parkinson's?
dopamine and acetylcholine Rivastigmine tartrate
-can lead to hepatotoxicity
-improves cognitive function in moderate Alzheimer's -s/e: diarrhea, headache,
depression, constipation Selegiline can delay the use of carbidopa-levodopa
therapy for Parkinson's Catechol ortho-methyltransferase inhibitors treat
on/off fluctuations of Parkinson's S/S of Parkinson's memory deficit, difficulty
swallowing, immobility, bradykinesia, tremors, rigidity
Anticholinergics are most frequently used for
drug-induced parkinsonism What
is Carbamazepine used for?
seizures, neuropathy, trigeminal neuralgia, bipolar disorder
What decreases folic acid?
anticonvulsants
What medication is used for lennox-gastaut syndrome?
Lamotrigine
Phenytoin
-protein bound drug