TEST BANK
Karch’s Focus on Nursing Pharmacology
Rebecca Tucker
, TEST BANK
Karch’s Focus on Nursing Pharmacology
Rebecca Tucker
Chapter 01 - Introduction to Drugs
b b b b b
Abnursebworkingbinbradiologybadministersbiodinebtobabpatientbwhobisbhavingbabcomputedbtomographyb(CT)bsc
an.bThebnursebworkingbonbtheboncologybunitbadministersbchemotherapybtobpatientsbwhobhavebcancer.b
AtbthebPublicbHealthbDepartment,babnursebadministersbabmeasles-mumps-
rubellab(MMR)bvaccinebtobab14-month-
oldbchildbasbabroutinebimmunization.bWhichbbranchbofbpharmacologybbestbdescribesbthebactionsbofballb
threebnurses?
PharmacoeconomicsbP
harmacotherapeuticsbP
harmacodynamicsbPha
rmacokineticsb Ans: B
Response:
Pharmacologybisbthebstudybofbthebbiologicbeffectsbofbchemicals.bNursesbarebinvolvedbwithbclinicalbpharm
acologyborbpharmacotherapeutics,bwhichbisbabbranchbofbpharmacologybthatbdealsbwithbthebusesbofbdrugsbt
obtreat,bprevent,bandbdiagnosebdisease.bThebradiologybnursebisbadministeringbabdrugbtobhelpbdiagnosebabdis
ease.bTheboncologybnursebisbadministeringbabdrugbtobhelpbtreatbabdisease.
Pharmacoeconomicsbincludesbanybcostsbinvolvedbinbdrugbtherapy.bPharmacodynamicsbinvolvesbhowbabdr
ugbaffectsbthebbodybandbpharmacokineticsbisbhowbthebbodybactsbonbthebbody.
Abphysicianbhasborderedbintramuscularb(IM)binjectionsbofbmorphine,babnarcotic,beveryb4bhoursbasbneededbforbp
ainbinbabmotorbvehiclebaccidentbvictim.bThebnursebisbawarebthisbdrugbhasbabhighbabusebpotential.
Underbwhatbcategorybwouldbmorphinebbebclassified?
SchedulebIbS
chedulebIIbSc
hedulebIIIbSc
hedulebIVbA
ns: B
Response:
NarcoticsbwithbabhighbabusebpotentialbarebclassifiedbasbSchedulebIIbdrugsbbecausebofbseverebdependence
, liability.bSchedulebIbdrugsbhavebhighbabusebpotentialbandbnobacceptedbmedicalbuse.bSchedulebIIIbdrugsb
havebablesserbabusebpotentialbthanbIIbandbanbacceptedbmedicalbuse.bSchedulebIVbdrugsbhaveblowbabuseb
potentialbandblimitedbdependencebliability.
WhenbinvolvedbinbphasebIIIbdrugbevaluationbstudies,bwhatbresponsibilitiesbwouldbthebnursebhave?b
Workingbwithbanimalsbwhobarebgivenbexperimentalbdrugs
ChoosingbappropriatebpatientsbtobbebinvolvedbinbthebdrugbstudybMonito
ringbandbobservingbpatientsbcloselybforbadversebeffectsbConductingbres
earchbtobdeterminebeffectivenessbofbthebdrugbAns:bC
Response:
PhasebIIIbstudiesbinvolvebusebofbabdrugbinbabvastbclinicalbpopulationbinbwhichbpatientsbarebaskedbtobrecordb
anybsymptomsbtheybexperiencebwhilebtakingbthebdrugs.bNursesbmaybbebresponsiblebforbhelpingbcollectban
dbanalyzebthebinformationbtobbebsharedbwithbthebFoodbandbDrugbAdministrationb(FDA)bbutbwouldbnotbco
nductbresearchbindependentlybbecausebnursesbdobnotbprescribebmedications.bUsebofbanimalsbinbdrugbtestin
gbisbdonebinbthebpreclinicalbtrials.bSelectbpatientsbwhobarebinvolvedbinbphasebIIbstudiesbtobparticipatebinbstu
diesbwherebthebparticipantsbhavebthebdiseasebthebdrugbisbintendedbtobtreat.bThesebpatientsbarebmonitoredbcl
oselybforbdrugbactionbandbadversebeffects.bPhasebIbstudiesbinvolvebhealthybhumanbvolunteersbwhobarebusu
allybpaidbforbtheirbparticipation.bNursesbmaybobservebforbadversebeffectsbandbtoxicity.
Whatbconceptbisbconsideredbwhenbgenericbdrugsbarebsubstitutedbforbbrandbnamebdrugs?bBioavailabi
lity
Criticalbconcentrationb
Distribution
Half-
lifeb Ans: A
Response:
Bioavailabilitybisbthebportionbofbabdosebofbabdrugbthatbreachesbthebsystemicbcirculationbandbisbavailablebt
obactbonbbodybcells.bBindersbusedbinbabgenericbdrugbmaybnotbbebthebsamebasbthosebusedbinbthebbrandbna
mebdrug.bTherefore,bthebwaybthebbodybbreaksbdownbandbusesbthebdrugbmaybdiffer,bwhichbmaybeliminate
babgenericbdrugbsubstitution.bCriticalbconcentrationbisbthebamountbofbabdrugbthatbisbneededbtobcausebabthe
rapeuticbeffectbandbshouldbnotbdifferbbetweenbgenericbandbbrandbnamebmedications.
Distributionbisbthebphasebofbpharmacokinetics,bwhichbinvolvesbthebmovementbofbabdrugbtobthebbody’sbt
issuesbandbisbthe
, samebinbgenericbandbbrandbnamebdrugs.bAbdrug’sbhalf-
lifebisbthebtimebitbtakesbforbthebamountbofbdrugbtobdecreasebtobhalfbthebpeakblevel,bwhichbshouldbnotbchange
bwhenbsubstitutingbabgenericbmedication.
Abnursebisbassessingbthebpatient’sbhomebmedicationbuse.bAfterblisteningbtobthebpatientblistbcurrentbmedications
,bthebnursebasksbwhatbprioritybquestion?
Dobyoubtakebanybgenericbmedications?
Arebanybofbthesebmedicationsborphanbdrugs?
Arebthesebmedicationsbsafebtobtakebduringbpregnancy?bD
obyoubtakebanybover-the-counterbmedications?
Ans: D
Response:
Itbisbimportantbforbthebnursebtobspecificallybquestionbusebofbover-the-
counterbmedicationsbbecausebpatientsbmaybnotbconsiderbthembimportant.bThebpatientbisbunlikelybtobknowb
thebmeaningbofborphanbdrugsbunlessbtheybtoobarebhealthbcarebproviders.bSafetybduringbpregnancy,busebofb
abgenericbmedication,borbclassificationbofborphanbdrugsbarebthingsbthebpatientbwouldbbebunablebtobanswerb
butbcouldbbebfoundbinbreferencebbooksbifbthebnursebwishesbtobresearchbthem.
Afterbcompletingbabcoursebonbpharmacologybforbnurses,bwhatbwillbthebnursebknow?bEverythi
ngbnecessarybforbsafebandbeffectivebmedicationbadministration
Currentbpharmacologicbtherapy;bthebnursebwillbnotbrequirebongoingbeducationbforb5byears.bG
eneralbdrugbinformation;bthebnursebcanbconsultbabdrugbguidebforbspecificbdrugbinformation.bT
hebdrugbactionsbthatbarebassociatedbwithbeachbclassificationbofbmedicationbAns: C
Response:
Afterbcompletingbabpharmacologybcoursebnursesbwillbhavebgeneralbdrugbinformationbneededbforbsafebandb
effectivebmedicationbadministrationbbutbwillbneedbtobconsultbabdrugbguidebforbspecificbdrugbinformationbb
eforebadministeringbanybmedication.bPharmacologybisbconstantlybchanging,bwithbnewbdrugsbenteringb theb
marketbandbnewbusesbforbexistingbdrugsbidentified.bContinuingbeducationbinbpharmacologybisbessentialbtob
safebpractice.bNursesbtendbtobbecomebfamiliarbwithbthebmedicationsbtheybadministerbmostboften,bbutbthere
bwillbalwaysbbebabneedbtobresearchbnewbdrugsbandbalsobthosebthebnursebisbnotbfamiliarbwithbbecausebnobnur
sebknowsballbmedications.
Karch’s Focus on Nursing Pharmacology
Rebecca Tucker
, TEST BANK
Karch’s Focus on Nursing Pharmacology
Rebecca Tucker
Chapter 01 - Introduction to Drugs
b b b b b
Abnursebworkingbinbradiologybadministersbiodinebtobabpatientbwhobisbhavingbabcomputedbtomographyb(CT)bsc
an.bThebnursebworkingbonbtheboncologybunitbadministersbchemotherapybtobpatientsbwhobhavebcancer.b
AtbthebPublicbHealthbDepartment,babnursebadministersbabmeasles-mumps-
rubellab(MMR)bvaccinebtobab14-month-
oldbchildbasbabroutinebimmunization.bWhichbbranchbofbpharmacologybbestbdescribesbthebactionsbofballb
threebnurses?
PharmacoeconomicsbP
harmacotherapeuticsbP
harmacodynamicsbPha
rmacokineticsb Ans: B
Response:
Pharmacologybisbthebstudybofbthebbiologicbeffectsbofbchemicals.bNursesbarebinvolvedbwithbclinicalbpharm
acologyborbpharmacotherapeutics,bwhichbisbabbranchbofbpharmacologybthatbdealsbwithbthebusesbofbdrugsbt
obtreat,bprevent,bandbdiagnosebdisease.bThebradiologybnursebisbadministeringbabdrugbtobhelpbdiagnosebabdis
ease.bTheboncologybnursebisbadministeringbabdrugbtobhelpbtreatbabdisease.
Pharmacoeconomicsbincludesbanybcostsbinvolvedbinbdrugbtherapy.bPharmacodynamicsbinvolvesbhowbabdr
ugbaffectsbthebbodybandbpharmacokineticsbisbhowbthebbodybactsbonbthebbody.
Abphysicianbhasborderedbintramuscularb(IM)binjectionsbofbmorphine,babnarcotic,beveryb4bhoursbasbneededbforbp
ainbinbabmotorbvehiclebaccidentbvictim.bThebnursebisbawarebthisbdrugbhasbabhighbabusebpotential.
Underbwhatbcategorybwouldbmorphinebbebclassified?
SchedulebIbS
chedulebIIbSc
hedulebIIIbSc
hedulebIVbA
ns: B
Response:
NarcoticsbwithbabhighbabusebpotentialbarebclassifiedbasbSchedulebIIbdrugsbbecausebofbseverebdependence
, liability.bSchedulebIbdrugsbhavebhighbabusebpotentialbandbnobacceptedbmedicalbuse.bSchedulebIIIbdrugsb
havebablesserbabusebpotentialbthanbIIbandbanbacceptedbmedicalbuse.bSchedulebIVbdrugsbhaveblowbabuseb
potentialbandblimitedbdependencebliability.
WhenbinvolvedbinbphasebIIIbdrugbevaluationbstudies,bwhatbresponsibilitiesbwouldbthebnursebhave?b
Workingbwithbanimalsbwhobarebgivenbexperimentalbdrugs
ChoosingbappropriatebpatientsbtobbebinvolvedbinbthebdrugbstudybMonito
ringbandbobservingbpatientsbcloselybforbadversebeffectsbConductingbres
earchbtobdeterminebeffectivenessbofbthebdrugbAns:bC
Response:
PhasebIIIbstudiesbinvolvebusebofbabdrugbinbabvastbclinicalbpopulationbinbwhichbpatientsbarebaskedbtobrecordb
anybsymptomsbtheybexperiencebwhilebtakingbthebdrugs.bNursesbmaybbebresponsiblebforbhelpingbcollectban
dbanalyzebthebinformationbtobbebsharedbwithbthebFoodbandbDrugbAdministrationb(FDA)bbutbwouldbnotbco
nductbresearchbindependentlybbecausebnursesbdobnotbprescribebmedications.bUsebofbanimalsbinbdrugbtestin
gbisbdonebinbthebpreclinicalbtrials.bSelectbpatientsbwhobarebinvolvedbinbphasebIIbstudiesbtobparticipatebinbstu
diesbwherebthebparticipantsbhavebthebdiseasebthebdrugbisbintendedbtobtreat.bThesebpatientsbarebmonitoredbcl
oselybforbdrugbactionbandbadversebeffects.bPhasebIbstudiesbinvolvebhealthybhumanbvolunteersbwhobarebusu
allybpaidbforbtheirbparticipation.bNursesbmaybobservebforbadversebeffectsbandbtoxicity.
Whatbconceptbisbconsideredbwhenbgenericbdrugsbarebsubstitutedbforbbrandbnamebdrugs?bBioavailabi
lity
Criticalbconcentrationb
Distribution
Half-
lifeb Ans: A
Response:
Bioavailabilitybisbthebportionbofbabdosebofbabdrugbthatbreachesbthebsystemicbcirculationbandbisbavailablebt
obactbonbbodybcells.bBindersbusedbinbabgenericbdrugbmaybnotbbebthebsamebasbthosebusedbinbthebbrandbna
mebdrug.bTherefore,bthebwaybthebbodybbreaksbdownbandbusesbthebdrugbmaybdiffer,bwhichbmaybeliminate
babgenericbdrugbsubstitution.bCriticalbconcentrationbisbthebamountbofbabdrugbthatbisbneededbtobcausebabthe
rapeuticbeffectbandbshouldbnotbdifferbbetweenbgenericbandbbrandbnamebmedications.
Distributionbisbthebphasebofbpharmacokinetics,bwhichbinvolvesbthebmovementbofbabdrugbtobthebbody’sbt
issuesbandbisbthe
, samebinbgenericbandbbrandbnamebdrugs.bAbdrug’sbhalf-
lifebisbthebtimebitbtakesbforbthebamountbofbdrugbtobdecreasebtobhalfbthebpeakblevel,bwhichbshouldbnotbchange
bwhenbsubstitutingbabgenericbmedication.
Abnursebisbassessingbthebpatient’sbhomebmedicationbuse.bAfterblisteningbtobthebpatientblistbcurrentbmedications
,bthebnursebasksbwhatbprioritybquestion?
Dobyoubtakebanybgenericbmedications?
Arebanybofbthesebmedicationsborphanbdrugs?
Arebthesebmedicationsbsafebtobtakebduringbpregnancy?bD
obyoubtakebanybover-the-counterbmedications?
Ans: D
Response:
Itbisbimportantbforbthebnursebtobspecificallybquestionbusebofbover-the-
counterbmedicationsbbecausebpatientsbmaybnotbconsiderbthembimportant.bThebpatientbisbunlikelybtobknowb
thebmeaningbofborphanbdrugsbunlessbtheybtoobarebhealthbcarebproviders.bSafetybduringbpregnancy,busebofb
abgenericbmedication,borbclassificationbofborphanbdrugsbarebthingsbthebpatientbwouldbbebunablebtobanswerb
butbcouldbbebfoundbinbreferencebbooksbifbthebnursebwishesbtobresearchbthem.
Afterbcompletingbabcoursebonbpharmacologybforbnurses,bwhatbwillbthebnursebknow?bEverythi
ngbnecessarybforbsafebandbeffectivebmedicationbadministration
Currentbpharmacologicbtherapy;bthebnursebwillbnotbrequirebongoingbeducationbforb5byears.bG
eneralbdrugbinformation;bthebnursebcanbconsultbabdrugbguidebforbspecificbdrugbinformation.bT
hebdrugbactionsbthatbarebassociatedbwithbeachbclassificationbofbmedicationbAns: C
Response:
Afterbcompletingbabpharmacologybcoursebnursesbwillbhavebgeneralbdrugbinformationbneededbforbsafebandb
effectivebmedicationbadministrationbbutbwillbneedbtobconsultbabdrugbguidebforbspecificbdrugbinformationbb
eforebadministeringbanybmedication.bPharmacologybisbconstantlybchanging,bwithbnewbdrugsbenteringb theb
marketbandbnewbusesbforbexistingbdrugsbidentified.bContinuingbeducationbinbpharmacologybisbessentialbtob
safebpractice.bNursesbtendbtobbecomebfamiliarbwithbthebmedicationsbtheybadministerbmostboften,bbutbthere
bwillbalwaysbbebabneedbtobresearchbnewbdrugsbandbalsobthosebthebnursebisbnotbfamiliarbwithbbecausebnobnur
sebknowsballbmedications.
