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Week 2 NCLEX review: NR 446 / NR446 (Latest Update 2025 / 2026) Collaborative Healthcare | 93 Comprehensive Questions & Answers | Grade A | 100% Correct – Chamberlain:

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Week 2 NCLEX review: NR 446 / NR446 (Latest Update 2025 / 2026) Collaborative Healthcare | 93 Comprehensive Questions & Answers | Grade A | 100% Correct – Chamberlain: Quiz_________________? What happens if a patient drinks alcohol while taking metronidazole? - Answer☑️ "Mixing metronidazole with alcohol? Bad life choice!" Triggers: Abdominal cramping Headache Vomiting Seizures ⚡ Teach your patients: "Just say no to the cocktail hour on Flagyl!" Quiz_________________? Can alcohol be consumed while on amoxicillin or fluticasone? - Answer☑️ "Sip smart, not sorry!" Alcohol in moderation won't cancel out Amoxicillin (antibiotic) Fluticasone (steroid nasal spray) But remind patients: moderation is key, and getting healthy comes first! Quiz_________________? What are the 3 things a nurse must do before giving an IV push med? - Answer☑️ "Right drug, right line, right patient!" Verify med matches the prescription Check IV site for redness, pain, or swelling Confirm 2 client identifiers Quiz_________________? Do you need to check for med compatibility when giving an IV push into a saline lock? - Answer☑️ ‍♀️ "No fluids = no compatibility check needed!" Since no fluid is infusing, compatibility doesn't apply Just flush, push, and flush again! Quiz_________________? Do you need to start a new IV or hang a fluid bag for a saline lock? - Answer☑️ "Nah, it's already locked and loaded!" Saline lock = capped line, ready to go No new IV or gravity bag needed Just flush before and after the IV push Quiz_________________? What's the rate for administering IV push meds? - Answer☑️ ⏱️ "Slow and steady wins the vein!" IV push = mL per minute Not per hour like drips—double-check your drug guide! Quiz_________________? Which meds should be held before dialysis? - Answer☑️ "Don't waste the dose—dialysis will drag it away!" Hold: Blood pressure meds Antibiotics Sodium polystyrene sulfonate (Kayexalate) These will be filtered out, so let dialysis do its job first! Quiz_________________? Why is polystyrene (Kayexalate) not needed right before dialysis? - Answer☑️ "Dialysis already scrubs out potassium!" Giving it right before dialysis is redundant Dialysis lowers K⁺ effectively on its own Quiz_________________? Can insulin be given before dialysis? - Answer☑️ "Insulin stays, especially with snacks!" Safe to give as long as the client eats ️ Clients can eat before and during dialysis Quiz_________________? When is the best time to give blood during dialysis? - Answer☑️ "Two birds, one machine!" Give blood during dialysis to avoid fluid overload Less risk, more efficiency! Quiz_________________? What's the first priority for treating a client needing N-acetylcysteine? - Answer☑️ "Get the line, then save the liver!" First: Insert a peripheral IV Next: Start normal saline bolus Then: Administer N-acetylcysteine (long infusion time) Quiz_________________? Is the client's clear liquid diet a high priority during treatment? - Answer☑️ "Food can wait—focus on saving the liver!" Clear liquids = lowest priority Treat the toxicity first, then feed later Quiz_________________? How often should the nurse check acetaminophen levels? - Answer☑️ "Don't guess—check every 8!" Draw levels now Then every 8 hours to monitor treatment effectiveness Quiz_________________? What does a high anti-Xa level mean for a client on heparin? - Answer☑️ "Too much drip—time to dip!" High anti-Xa = too much heparin Slow down the infusion (per protocol) No bolus. Don't stop the drip—just decrease the rate Quiz_________________? How do you adjust a heparin drip if anti-Xa is 0.8 and running at 18 mL/hr? - Answer☑️ "Drop it down by 1!" Protocol says: decrease by 1 unit/kg/hr So change from 18 mL/hr → 17 mL/hr Quiz_________________? What do you do after changing the heparin rate? - Answer☑️ ⏰ "Mark your calendar—labs in 6!" Schedule a repeat anti-Xa lab in 6 hours Quiz_________________? What should you assess for when anti-Xa levels are high? - Answer☑️ "Bleed alert!" Watch for: Petechiae Bruising IV site bleeding Bleeding is the big danger now—not clotting! Quiz_________________? Why is anti-Xa better than aPTT for heparin monitoring? - Answer☑️ "More accurate, fewer adjustments!" Anti-Xa = precise monitoring of heparin Less back-and-forth than aPTT Target range: 0.3-0.7 units/mL (may vary by case) Quiz_________________? What type of IV access is best for chemotherapy, and why? - Answer☑️ "Go central or go home!" Use a central line or port Peripheral lines are too fragile for chemo's harsh consistency Quiz_________________? What should the nurse check before starting chemotherapy? - Answer☑️ "Blood return = green light!" Confirm patency by checking for blood return No blood return? Don't infuse—risk of tissue damage! Quiz_________________? What's the difference between infiltration and extravasation? - Answer☑️ "Both bad, but one's next-level nasty!" Infiltration (non-vesicant): Irritates tissue Extravasation (vesicant): Erodes and damages tissue permanently! Watch for: Redness, bruising, streaking, pus

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Week 2 NCLEX review: NR 446 /
NR446 (Latest Update )
Collaborative Healthcare | 93
Comprehensive Questions &
Answers | Grade A | 100% Correct –
Chamberlain:
Quiz_________________?
What happens if a patient drinks alcohol while taking metronidazole? -
Answer☑️
🚫🍷 "Mixing metronidazole with alcohol? Bad life choice!"
Triggers:
Abdominal cramping
Headache
Vomiting
Seizures ⚡
Teach your patients: "Just say no to the cocktail hour on Flagyl!"

Quiz_________________?
Can alcohol be consumed while on amoxicillin or fluticasone? -
Answer☑️
✅🍷 "Sip smart, not sorry!"
Alcohol in moderation won't cancel out
Amoxicillin (antibiotic)
Fluticasone (steroid nasal spray)
But remind patients: moderation is key, and getting healthy comes first!



1

, Quiz_________________?
What are the 3 things a nurse must do before giving an IV push med? -
Answer☑️
💉 "Right drug, right line, right patient!"
Verify med matches the prescription
Check IV site for redness, pain, or swelling
Confirm 2 client identifiers ✅✅

Quiz_________________?
Do you need to check for med compatibility when giving an IV push into a saline lock? -
Answer☑️
🙅‍♀️ "No fluids = no compatibility check needed!"
Since no fluid is infusing, compatibility doesn't apply
Just flush, push, and flush again!

Quiz_________________?
Do you need to start a new IV or hang a fluid bag for a saline lock? -
Answer☑️
"Nah, it's already locked and loaded!"
Saline lock = capped line, ready to go
No new IV or gravity bag needed
Just flush before and after the IV push 🚿

Quiz_________________?
What's the rate for administering IV push meds? -
Answer☑️
⏱️ "Slow and steady wins the vein!"
IV push = mL per minute
Not per hour like drips—double-check your drug guide!

Quiz_________________?
Which meds should be held before dialysis? -
Answer☑️
💊 "Don't waste the dose—dialysis will drag it away!"
Hold:
Blood pressure meds
Antibiotics
Sodium polystyrene sulfonate (Kayexalate)
These will be filtered out, so let dialysis do its job first!

Quiz_________________?
Why is polystyrene (Kayexalate) not needed right before dialysis? -
Answer☑️
⚡ "Dialysis already scrubs out potassium!"


2

, Giving it right before dialysis is redundant
Dialysis lowers K⁺ effectively on its own

Quiz_________________?
Can insulin be given before dialysis? -
Answer☑️
✅💉 "Insulin stays, especially with snacks!"
Safe to give as long as the client eats 🍽️
Clients can eat before and during dialysis

Quiz_________________?
When is the best time to give blood during dialysis? -
Answer☑️
🌀 "Two birds, one machine!"
Give blood during dialysis to avoid fluid overload
Less risk, more efficiency!

Quiz_________________?
What's the first priority for treating a client needing N-acetylcysteine? -
Answer☑️
"Get the line, then save the liver!"
First: Insert a peripheral IV
Next: Start normal saline bolus
Then: Administer N-acetylcysteine (long infusion time)

Quiz_________________?
Is the client's clear liquid diet a high priority during treatment? -
Answer☑️
"Food can wait—focus on saving the liver!"
Clear liquids = lowest priority
Treat the toxicity first, then feed later

Quiz_________________?
How often should the nurse check acetaminophen levels? -
Answer☑️
"Don't guess—check every 8!"
Draw levels now
Then every 8 hours to monitor treatment effectiveness

Quiz_________________?
What does a high anti-Xa level mean for a client on heparin? -
Answer☑️
📈 "Too much drip—time to dip!"
High anti-Xa = too much heparin
Slow down the infusion (per protocol)


3

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