NR 566 Advanced Pharmacology Final Exam 2025/2026 |
Complete Test Bank | 100 Verified Questions and Correct
Answers | Updated & Graded A+
Overview
The NR 566 Advanced Pharmacology Final Exam 2025/2026 Test Bank provides a complete, updated
collection of 100 verified, high-quality exam-style questions with accurate answers and concise
rationales.
This resource is designed for Nurse Practitioner, FNP, and DNP learners preparing for advanced
pharmacology finals, board-style exams, or certification reviews.
It integrates clinical application, drug mechanisms, and safe prescribing principles, ensuring full
mastery of the pharmacological concepts required for competent advanced practice.
Introduction
This comprehensive 2025/2026 edition of the NR 566 Pharmacology Test Bank encompasses all major
therapeutic classes, emphasizing pharmacokinetics, pharmacodynamics, adverse effects,
contraindications, and evidence-based prescribing.
Key domains include:
Cardiovascular and antihypertensive therapy
Neuropsychiatric and pain management pharmacology
Antimicrobial, antiviral, and antifungal therapies
Endocrine and diabetic pharmacology
Pulmonary, GI, and renal systems
Women’s and men’s health drugs
Geriatric, pediatric, and special-population considerations
Each question reflects real-world clinical decision-making, integrating diagnostic reasoning,
therapeutic monitoring, and safe medication practice.
This test bank ensures learners achieve advanced comprehension, confidence, and accuracy aligned with
current AACN, AANP, and ANCC pharmacology standards.
Answer Format
,All correct answers appear in bold green text for quick visual identification.
Each item is immediately followed by a concise, evidence-based rationale that:Reinforces key
pharmacologic mechanisms
Q1
A patient with hypertension develops a chronic dry cough on lisinopril. What is the best
alternative?
Losartan
Rationale: ARBs provide similar RAAS inhibition without bradykinin accumulation that causes
cough.
Q2
Which antidiabetic medication should be discontinued before contrast dye administration?
Metformin
Rationale: Prevents risk of lactic acidosis in case of renal injury from contrast.
Q3
A 28-year-old woman taking isotretinoin must adhere to which safety protocol?
Enroll in iPLEDGE and use two forms of contraception
Rationale: Isotretinoin is highly teratogenic.
Q4
Which antidepressant is most likely to cause sexual dysfunction?
Fluoxetine
Rationale: SSRIs decrease libido via serotonergic inhibition.
Q5
What is the mechanism of action of thiazide diuretics?
Inhibit sodium reabsorption in the distal convoluted tubule
Rationale: Reduces plasma volume and lowers blood pressure.
Q6
Which antibiotic carries a black-box warning for tendinitis and tendon rupture?
, Ciprofloxacin
Rationale: Fluoroquinolone class effect, especially in older adults.
Q7
Which drug is first-line for chronic heart failure with reduced ejection fraction?
ACE inhibitor
Rationale: Reduces afterload and mortality by inhibiting RAAS activation.
Q8
What should be monitored with long-term amiodarone therapy?
Thyroid, liver, and pulmonary function
Rationale: Amiodarone accumulates in tissues causing systemic toxicity.
Q9
Which insulin has the longest duration of action?
Insulin degludec (Tresiba)
Rationale: Ultra-long-acting basal insulin with >24-hour coverage.
Q10
Which medication should never be given with nitrates?
Sildenafil
Rationale: Additive vasodilation → severe hypotension.
Q11
What is the preferred treatment for a pregnant patient with hypertension?
Labetalol
Rationale: Safe in pregnancy; ACEIs/ARBs contraindicated.
Q12
Which antidepressant is also used for smoking cessation?
Bupropion
Rationale: Dopamine-norepinephrine reuptake inhibitor; minimal sexual side effects.
Complete Test Bank | 100 Verified Questions and Correct
Answers | Updated & Graded A+
Overview
The NR 566 Advanced Pharmacology Final Exam 2025/2026 Test Bank provides a complete, updated
collection of 100 verified, high-quality exam-style questions with accurate answers and concise
rationales.
This resource is designed for Nurse Practitioner, FNP, and DNP learners preparing for advanced
pharmacology finals, board-style exams, or certification reviews.
It integrates clinical application, drug mechanisms, and safe prescribing principles, ensuring full
mastery of the pharmacological concepts required for competent advanced practice.
Introduction
This comprehensive 2025/2026 edition of the NR 566 Pharmacology Test Bank encompasses all major
therapeutic classes, emphasizing pharmacokinetics, pharmacodynamics, adverse effects,
contraindications, and evidence-based prescribing.
Key domains include:
Cardiovascular and antihypertensive therapy
Neuropsychiatric and pain management pharmacology
Antimicrobial, antiviral, and antifungal therapies
Endocrine and diabetic pharmacology
Pulmonary, GI, and renal systems
Women’s and men’s health drugs
Geriatric, pediatric, and special-population considerations
Each question reflects real-world clinical decision-making, integrating diagnostic reasoning,
therapeutic monitoring, and safe medication practice.
This test bank ensures learners achieve advanced comprehension, confidence, and accuracy aligned with
current AACN, AANP, and ANCC pharmacology standards.
Answer Format
,All correct answers appear in bold green text for quick visual identification.
Each item is immediately followed by a concise, evidence-based rationale that:Reinforces key
pharmacologic mechanisms
Q1
A patient with hypertension develops a chronic dry cough on lisinopril. What is the best
alternative?
Losartan
Rationale: ARBs provide similar RAAS inhibition without bradykinin accumulation that causes
cough.
Q2
Which antidiabetic medication should be discontinued before contrast dye administration?
Metformin
Rationale: Prevents risk of lactic acidosis in case of renal injury from contrast.
Q3
A 28-year-old woman taking isotretinoin must adhere to which safety protocol?
Enroll in iPLEDGE and use two forms of contraception
Rationale: Isotretinoin is highly teratogenic.
Q4
Which antidepressant is most likely to cause sexual dysfunction?
Fluoxetine
Rationale: SSRIs decrease libido via serotonergic inhibition.
Q5
What is the mechanism of action of thiazide diuretics?
Inhibit sodium reabsorption in the distal convoluted tubule
Rationale: Reduces plasma volume and lowers blood pressure.
Q6
Which antibiotic carries a black-box warning for tendinitis and tendon rupture?
, Ciprofloxacin
Rationale: Fluoroquinolone class effect, especially in older adults.
Q7
Which drug is first-line for chronic heart failure with reduced ejection fraction?
ACE inhibitor
Rationale: Reduces afterload and mortality by inhibiting RAAS activation.
Q8
What should be monitored with long-term amiodarone therapy?
Thyroid, liver, and pulmonary function
Rationale: Amiodarone accumulates in tissues causing systemic toxicity.
Q9
Which insulin has the longest duration of action?
Insulin degludec (Tresiba)
Rationale: Ultra-long-acting basal insulin with >24-hour coverage.
Q10
Which medication should never be given with nitrates?
Sildenafil
Rationale: Additive vasodilation → severe hypotension.
Q11
What is the preferred treatment for a pregnant patient with hypertension?
Labetalol
Rationale: Safe in pregnancy; ACEIs/ARBs contraindicated.
Q12
Which antidepressant is also used for smoking cessation?
Bupropion
Rationale: Dopamine-norepinephrine reuptake inhibitor; minimal sexual side effects.
