Part I: Basic Immunologic Mechanisms
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1. Highlights of Innate and Adaptive Immune Systems
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2. Soluble Mediators of the Immune System
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3. Antigens and Antibodies b b
4. Cellular Activities and Clinical Disorders of Innate and Adaptive Immunity
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Part II: The Theory of Immunologic and Serologic Procedures
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5. Basic Safety in the Immunology-Serology Laboratory
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6. Quality Assurance and Quality Control Practices
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7. Basic Serologic Laboratory: Techniques and Clinical Applications
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8. Precipitation and Particle Agglutination Methods b b b b
9. Electrophoresis Techniques b
10. Labeling Techniques in Immunoassay b b b
11. Flow Cytometry b
12. Molecular Laboratory Techniques b b
Part III: Immunologic Manifestations of Infectious Diseases
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13. Infectious Diseases: Overview & TORCH Diseases b b b b b
14. Streptococcal Infections b
15. Syphilis
16. Vector-Borne Diseases b
17. Infectious Mononucleosis b
18. Viral Hepatitis b
Part IV: Immune Disorders
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19. Primary and Acquired (Secondary) Immune Deficiencies
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20. Hypersensitivity Reactions b
21. Immunoproliferative Disorders b
22. Tolerance, Autoimmunity and Autoimmune Disorders b b b b
23. Systemic Lupus Erythematosus b b
,24. Rheumatoid Arthritis b
Part V: Transplantation & Tumor Immunology
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25. Transplantation: HLA, Solid Organ, and Hematopoietic Stem Cells
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26. Tumor Immunology and Up-to-Date Applications of Next Generation Sequencing
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Part VI: Vaccines
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27. Primer on Vaccines b b
Chapter 01: Highlights ofthe Innate andAdaptive Immune Systems
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MULTIPLE CHOICE b
1. The―father‖ ofimmunologyisgenerallyconsidered to be
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a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS: B b
, Louis Pasteur is generally considered to be the ―father of immunology.‖
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DIF: Cognitive Level: I b b
2. An early form of immunization was practiced by the
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a. Romans.
b. Greeks.
c. Chinese.
d. Native Americans. b
ANS: C b
Beginning about 1000 AD, the Chinese practiced a form of immunization by inhaling dried powders
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derived from the crusts of smallpox lesions.
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DIF: Cognitive Level: I b b
3. A specific function of the immune system is to
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a. recognize self from nonself. b b b
b. defend the body against nonself. b b b b
c. amplify specific functions. b b
d. Both A and B. b b b
ANS: D b
The function ofthe immune system is to recognize self from nonself and defend the body against
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nonself. Such a system is necessary for survival. The immune system also has nonspecific
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effector mechanisms that usually amplify the specific functions. Nonspecific components of the
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immune system include mononuclear phagocytes, polymorphonuclear leukocytes, and soluble
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factors (e.g., complement).
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DIF: Cognitive Level: I b b
4. An undesirable consequence of immunity is
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a. natural resistance. b
b. acquired resistance to infectious diseases. b b b b