Maryville University – NURS 615 Advanced
Pathophysiology Exam 2 Questions and Answers
2024 A+ (Updated for 2025/2026) – Complete Exam
Preparation Material
Aminoglycosides block protein production and consist of which antibiotics? - gentamicin,
streptomycin, tobramycin
Anti-depressant that is to be used with caution in cardiac patients due to behaving like class 1
anti-arrythmics? - TCAs
Are cephalosporins bactericidal or bacteriostatic? - Bacteriocidal
Are PCNs bactericidal or bactriostatic? - Bactericidal
Are sulfonamides bacteriocidal or bacteriostatic? - Bacteriostatic
Are tetracyclines bacteriostatic or bacteriocidal? - bacteriostatic
Are tetracyclines broad or narrow in spectruM? - Broad and they have a lot of resistance issues
Benzodiazepines affect what neurotransmitter and how? - Increases the effects of GABA
Can valproate (Depakote) be used during pregnancy? - It is a known teratogen. If needed, must
be used after 1st trimester.
, Do cephalosporins become more broad or narrow in spectrum as you go up in generation? -
More broad spectrum
Does Lithium have a broad or narrow therapeutic range? - Narrow therapeutic range; toxicity
may show nausea and drowsiness
How and when is silver sulfadiazine used? - Used for burns, but its usefulness is poor
How are acyclovir and valcyclovir metabolized? - 10% by the liver and 90% by the kidneys
How are sexual side effects linked to SSRIs? - Sexual side effects may start after 1 month;
especially common in Paxil
How do anti-TB drugs work? - They inhibit the formation of mycolic acids which are an
important part of the cell wall
How do anti-virals (neuramidase inhibitors) work? - These medications break the bond that
attaches the viral particles to the host cell and keeps them from replicating
How do anti-virals for HSV and VZV work? - They block an enzyme that is essential in the
production of new viruses so they can't replicate
How do SSRIs work? - They block the reuptake of serotonin at the synaptic cleft so there is more
serotonin around
How do you discontinue an SSRI? - Taper by reducing the dose by 50% for 3-4 days
Pathophysiology Exam 2 Questions and Answers
2024 A+ (Updated for 2025/2026) – Complete Exam
Preparation Material
Aminoglycosides block protein production and consist of which antibiotics? - gentamicin,
streptomycin, tobramycin
Anti-depressant that is to be used with caution in cardiac patients due to behaving like class 1
anti-arrythmics? - TCAs
Are cephalosporins bactericidal or bacteriostatic? - Bacteriocidal
Are PCNs bactericidal or bactriostatic? - Bactericidal
Are sulfonamides bacteriocidal or bacteriostatic? - Bacteriostatic
Are tetracyclines bacteriostatic or bacteriocidal? - bacteriostatic
Are tetracyclines broad or narrow in spectruM? - Broad and they have a lot of resistance issues
Benzodiazepines affect what neurotransmitter and how? - Increases the effects of GABA
Can valproate (Depakote) be used during pregnancy? - It is a known teratogen. If needed, must
be used after 1st trimester.
, Do cephalosporins become more broad or narrow in spectrum as you go up in generation? -
More broad spectrum
Does Lithium have a broad or narrow therapeutic range? - Narrow therapeutic range; toxicity
may show nausea and drowsiness
How and when is silver sulfadiazine used? - Used for burns, but its usefulness is poor
How are acyclovir and valcyclovir metabolized? - 10% by the liver and 90% by the kidneys
How are sexual side effects linked to SSRIs? - Sexual side effects may start after 1 month;
especially common in Paxil
How do anti-TB drugs work? - They inhibit the formation of mycolic acids which are an
important part of the cell wall
How do anti-virals (neuramidase inhibitors) work? - These medications break the bond that
attaches the viral particles to the host cell and keeps them from replicating
How do anti-virals for HSV and VZV work? - They block an enzyme that is essential in the
production of new viruses so they can't replicate
How do SSRIs work? - They block the reuptake of serotonin at the synaptic cleft so there is more
serotonin around
How do you discontinue an SSRI? - Taper by reducing the dose by 50% for 3-4 days
