1|Page
NURS 5334 ANTIMICROBIALS FINAL EXAM VERSION 1 AND 2
NEWEST 2025/2026 ACTUAL EXAM WITH COMPLETE QUESTIONS
AND CORRECT DETAILED ANSWERS (100% VERIFIED ANSWERS)
|ALREADY GRADED A+| ||PROFESSOR VERIFIED||
Which of the following cephalosporins has activity against gram
negative anaerobic pathogens such as Bacteroides Fragilis -
ANSWER-Cefoxitin [Mefoxin]
20 year comes in with UTI. Based on symptoms and UA,
diagnosed with UTI. Cultures reveal Enterococcus faecalis that is
sensitive to all antibiotics usually tested for potential treatment.
Which of the following is an appropriate oral option to treat the
UTI - ANSWER-Amoxicillin
1st line antibiotic for patient with comorbidities
[immunosuppression] who has pneumonia and can be treated as
an outpatient would be - ANSWER-Levofloxacin
John is 4 week old infant who has been diagnosed with
Chlamydial pneumonia. An appropriate treatment for his
pneumonia would be - ANSWER-Erythromycin
,2|Page
Which is primary method of B-lactamase resistance with
streptococcus pneumoniae - ANSWER-Modification of target site
An 80 year old patient will be taking Cefdinir [Omnicef]. Before
initiating therapy, the NP should order - ANSWER-Creatinine
clearance
Bacteriostatic - ANSWER-ECSTaTic
Erythromycin
Clindamycin
Sulfamethoxazole
Trimethroprim
Tetracycline
Chloramphenicol
Minimum Bactericidal Concentration (MBC) - ANSWER-Lowest
concentration of an antibacterial agent requirement to kill a
particular bacterium
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Minimum Inhibitory Concentration (MIC) - ANSWER-Lowest
concentration of an antimicrobial agent that will inhibit the visible
growth of a microorganism after overnight incubation (In vitro)
Antibiogram - ANSWER-Chart of local resistance patterns to
antibiotics developed by laboratories
When is combination therapy appropriate - ANSWER-- Febrile,
leukopenic patient
- Infections with multiple pathogens
- Synergism (i.e. Trimethoprim/sulfamethoxazole)
- TB
- HIV
Disadvantages of combo thearpy - ANSWER-Risk of allergies
Risk of superinfection
Risk of drug interactions
Increased cost
, 4|Page
Antibiotics to use with caution - ANSWER-Aminoglycosides
Vancomycin
Clindamycin
Gentamycin (effects even after discontinues, allows once daily
dosing)
Imipenem
Cilastatin (Helps Imipenem work more efficiently)
Trimpethoprim
Nitrofurantoin (Pulmonary Fibrosis)
Antibiotics contraindicated in pregnancy - ANSWER-
Chloramphenicol-gray baby syndrome
Erythromycin estolate- cholestatic hepatitis in mother
Tetracycline- limb abnormalities, dental staining, decrease in bone
growth
Fluoroquinolones- abnormalities in cartilage
TMP/SMX- hemolysis, increased risk of kernicterus
-Dose on TMP portion of the drug in children(4mg/Kg q 12hr)
NURS 5334 ANTIMICROBIALS FINAL EXAM VERSION 1 AND 2
NEWEST 2025/2026 ACTUAL EXAM WITH COMPLETE QUESTIONS
AND CORRECT DETAILED ANSWERS (100% VERIFIED ANSWERS)
|ALREADY GRADED A+| ||PROFESSOR VERIFIED||
Which of the following cephalosporins has activity against gram
negative anaerobic pathogens such as Bacteroides Fragilis -
ANSWER-Cefoxitin [Mefoxin]
20 year comes in with UTI. Based on symptoms and UA,
diagnosed with UTI. Cultures reveal Enterococcus faecalis that is
sensitive to all antibiotics usually tested for potential treatment.
Which of the following is an appropriate oral option to treat the
UTI - ANSWER-Amoxicillin
1st line antibiotic for patient with comorbidities
[immunosuppression] who has pneumonia and can be treated as
an outpatient would be - ANSWER-Levofloxacin
John is 4 week old infant who has been diagnosed with
Chlamydial pneumonia. An appropriate treatment for his
pneumonia would be - ANSWER-Erythromycin
,2|Page
Which is primary method of B-lactamase resistance with
streptococcus pneumoniae - ANSWER-Modification of target site
An 80 year old patient will be taking Cefdinir [Omnicef]. Before
initiating therapy, the NP should order - ANSWER-Creatinine
clearance
Bacteriostatic - ANSWER-ECSTaTic
Erythromycin
Clindamycin
Sulfamethoxazole
Trimethroprim
Tetracycline
Chloramphenicol
Minimum Bactericidal Concentration (MBC) - ANSWER-Lowest
concentration of an antibacterial agent requirement to kill a
particular bacterium
,3|Page
Minimum Inhibitory Concentration (MIC) - ANSWER-Lowest
concentration of an antimicrobial agent that will inhibit the visible
growth of a microorganism after overnight incubation (In vitro)
Antibiogram - ANSWER-Chart of local resistance patterns to
antibiotics developed by laboratories
When is combination therapy appropriate - ANSWER-- Febrile,
leukopenic patient
- Infections with multiple pathogens
- Synergism (i.e. Trimethoprim/sulfamethoxazole)
- TB
- HIV
Disadvantages of combo thearpy - ANSWER-Risk of allergies
Risk of superinfection
Risk of drug interactions
Increased cost
, 4|Page
Antibiotics to use with caution - ANSWER-Aminoglycosides
Vancomycin
Clindamycin
Gentamycin (effects even after discontinues, allows once daily
dosing)
Imipenem
Cilastatin (Helps Imipenem work more efficiently)
Trimpethoprim
Nitrofurantoin (Pulmonary Fibrosis)
Antibiotics contraindicated in pregnancy - ANSWER-
Chloramphenicol-gray baby syndrome
Erythromycin estolate- cholestatic hepatitis in mother
Tetracycline- limb abnormalities, dental staining, decrease in bone
growth
Fluoroquinolones- abnormalities in cartilage
TMP/SMX- hemolysis, increased risk of kernicterus
-Dose on TMP portion of the drug in children(4mg/Kg q 12hr)
