TEST BANK for Katzung’s Basic & Clinical Pharmacology (16th Edition, Vanderah) | Latest Update 2025/2026 | Verified & Complete

TEST BANK FOR BASIC AND CLINICAL PHARMACOLOGY
16TH EDITION KATZUNG’S TESTBANK /ALL CHS 1-
66/COMPLETE GUIDE .

,CH 1. Introduction: The Nature of Drugs & Drug Development & Regulation
E E E E E E E E E E E




1. A nurse working in radiology administers iodine to a hospital client who
E E E E E E E E E E E


is having a computed tomography (CT) scan. The nursing attendant
E E E E E E E E E E


working on the oncology unit administers chemotherapy to hospital
E E E E E E E E E


clients who have cancer. At the Public Health Department, a nursing
E E E E E E E E E E E


attendant administers a measles-mumps-rubella (MMR) vaccine to a 14-
E E E E E E E E E E


month-old child as a routine immunization. Which branch of
E E E E E E E E


pharmacology best describes the actions of all three
E E E E E E E E


nursing attendants? E



A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ACCURATE CHOICE:- E B
Reasoning :->>>>>> E




Pharmacology is the study of the biologic effects of chemicals. Nursing
E E E E E E E E E E


attendants are involved with clinical pharmacology or
E E E E E E E


pharmacotherapeutics, which is a branch of pharmacology that deals with
E E E E E E E E E E


the uses of drugs to treat,prevent, and diagnose disease. The radiology
E E E E E E E E E E E E


nursing attendant is administering a drug to help diagnose a disease. The
E E E E E E E E E E E E


oncology nursing attendant is administering a drug to help treat a disease.
E E E E E E E E E E E E


Pharmacoeconomics includes any costs involved in drug therapy.
E E E E E E E E


Pharmacodynamics involves how a drug affects the body and E E E E E E E E


pharmacokinetics is how the body acts on the body. E E E E E E E E




2. When involved in phase III drug evaluation studies,
E E E E E E E


whatresponsibilities would the nursing attendant have?
E E E E E E E




A) Working with animals who are given experimental drugs
E E E E E E E




B) Choosing appropriate hospital clients to be involved in the drug study
E E E E E E E E E E




C) Monitoring and observing hospital clients closely for adverse effects
E E E E E E E E




D) Conducting research to determine effectiveness of the drug
E E E E E E E

,ACCURATE CHOICE:- E C
Reasoning:->>>>>>

Phase III studies involve use of a drug in a vast clinical population in
E E E E E E E E E E E E E


whichhospital clients are asked to record any symptoms they experience
E E E E E E E E E E E


while taking the drugs. Nursing attendants may be responsible for helping
E E E E E E E E E E E


collect and analyzethe information to be shared with the Food and Drug
E E E E E E E E E E E E E


Administration (FDA)but would not conduct research independently
E E E E E E E E


because nursing attendants donot prescribe medications. Use of animals
E E E E E E E E E E


in drug testing is done in the preclinical trials. Select hospital clients who
E E E E E E E E E E E E E


are involved in phase II studies to participate in studies where the
E E E E E E E E E E E E


participants have the disease the drug is intended to treat. These hospital
E E E E E E E E E E E E


clients are monitored closely for drug action and adverse effects. Phase I
E E E E E E E E E E E E


studies involve healthy human volunteers who are usually paid for their
E E E E E E E E E E E


participation. Nursing attendants may observe for
E E E E E E


adverse effects and toxicity. E E E




3. A physician has ordered intramuscular (IM) injections of morphine, a
E E E E E E E E E


narcotic, every 4 hours as needed for pain in a motor vehicle accident
E E E E E E E E E E E E E


victim.The nursing attendant is aware this drug has a high abuse potential.
E E E E E E E E E E E E E


Under what category would morphine be classified?
E E E E E E E




A) Schedule I E




B) Schedule II E




C) Schedule III E




D) Schedule IV E




ACCURATE CHOICE:- E B
Reasoning:->>>>>>

Narcotics with a high abuse potential are classified as Schedule II drugs
E E E E E E E E E E E


because of severe dependence liability. Schedule I drugs have high abuse
E E E E E E E E E E E


potential and no accepted medical use. Schedule III drugs have a lesser
E E E E E E E E E E E E


abuse potential than II and an accepted medical use. Schedule IV drugs
E E E E E E E E E E E E


havelow abuse potential and limited dependence liability.
E E E E E E E E




4. What concept is considered when generic drugs are substituted for
E E E E E E E E E


brandname drugs?
E E E




A) Bioavailability

, Page 5 of 822 E E E




B) Critical concentration E




C) Distribution
D) Half-life
ACCURATE CHOICE:-AE




Reasoning:->>>>>>

Bioavailability is the portion of a dose of a drug that reaches the systemic
E E E E E E E E E E E E E


circulation and is available to act on body cells. Binders used in a generic
E E E E E E E E E E E E E E


drug may not be the same as those used in the brand name drug.
E E E E E E E E E E E E E E


Therefore, the way the body breaks down and uses the drug may differ,
E E E E E E E E E E E E E


which may eliminate a generic drug substitution. Critical concentration is
E E E E E E E E E E


the amount ofa drug that is needed to cause a therapeutic effect and
E E E E E E E E E E E E E E


should not differ between generic and brand name medications.
E E E E E E E E E


Distribution is the phase of pharmacokinetics, which involves the
E E E E E E E E E


movement of a drug to the bodys tissues and is the same in generic and
E E E E E E E E E E E E E E E


brand name drugs. A drugs half-life isthe time it takes for the amount of
E E E E E E E E E E E E E E E


drug to decrease to half the peak level, which should not change when
E E E E E E E E E E E E E


substituting a generic medication.
E E E E




5. A nursing attendant is assessing the hospital clients home medication use. After
E E E E E E E E E E E


listening to the hospital client list current medications, the nursing
E E E E E E E E E


Eattendant askswhat priority question? E E E E




A) Do you take any generic medications?
E E E E E




B) Are any of these medications orphan drugs?
E E E E E E




C) Are these medications safe to take during pregnancy?
E E E E E E E




D) Do you take any over-the-counter medications?
E E E E E




ACCURATE CHOICE:-
E D
Reasoning:->>>>>>

It is important for the nursing attendant to specifically question use of
E E E E E E E E E E E


Eover- the-counter medications because hospital clients may not consider
E E E E E E E E


Ethem important. The hospital client is unlikely to know the meaning of
E E E E E E E E E E E


Eorphan drugs unless they too are primary health care providers. Safety
E E E E E E E E E E


Eduring pregnancy, use of a genericmedication, or classification of orphan
E E E E E E E E E E


Edrugs are things the hospital client would be unable to answer but could
E E E E E E E E E E E E


Ebe found in reference books if the nursing attendant wishes to research
E E E E E E E E E E E


Ethem.