TEST BANK – Katzung’s Basic and Clinical Pharmacology, 16th Edition (Lange Medical Books) by Todd W. Vanderah | Updated 2025/2026 Exam Guide

TEST BANK FOR BASIC AND CLINICAL PHARMACOLOGY
16TH EDITION KATZUNG’S TESTBANK /ALL CHS 1-
66/COMPLETE GUIDE 2024-2025

,CH 1. Introduction: The Nature of Drugs & Drug Development & Regulation
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1. A nurse working in radiology administers iodine to a hospital client who
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is having a computed tomography (CT) scan. The nursing attendant
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working on the oncology unit administers chemotherapy to hospital
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clients who have cancer. At the Public Health Department, a nursing
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attendant administers a measles-mumps-rubella (MMR) vaccine to a 14-
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month-old child as a routine immunization. Which branch of
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pharmacology best describes the actions of all three
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nursing attendants? V



A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ACCURATE CHOICE:- V B
Reasoning :->>>>>> V




Pharmacology is the study of the biologic effects of chemicals. Nursing
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attendants are involved with clinical pharmacology or
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pharmacotherapeutics, which is a branch of pharmacology that deals with
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the uses of drugs to treat,prevent, and diagnose disease. The radiology
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nursing attendant is administering a drug to help diagnose a disease. The
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oncology nursing attendant is administering a drug to help treat a disease.
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Pharmacoeconomics includes any costs involved in drug therapy.
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Pharmacodynamics involves how a drug affects the body and V V V V V V V V


pharmacokinetics is how the body acts on the body. V V V V V V V V




2. When involved in phase III drug evaluation studies,
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whatresponsibilities would the nursing attendant have?
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A) Working with animals who are given experimental drugs
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B) Choosing appropriate hospital clients to be involved in the drug study
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C) Monitoring and observing hospital clients closely for adverse effects
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D) Conducting research to determine effectiveness of the drug
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,ACCURATE CHOICE:-
V C
Reasoning:->>>>>>

Phase III studies involve use of a drug in a vast clinical population in
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whichhospital clients are asked to record any symptoms they experience
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Vwhile taking the drugs. Nursing attendants may be responsible for
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Vhelping collect and analyzethe information to be shared with the Food
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Vand Drug Administration (FDA)but would not conduct research
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Vindependently because nursing attendants donot prescribe medications.
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VUse of animals in drug testing is done in the preclinical trials. Select
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Vhospital clients who are involved in phase II studies to participate in
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Vstudies where the participants have the disease the drug is intended to
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Vtreat. These hospital clients are monitored closely for drug action and
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Vadverse effects. Phase I studies involve healthy human volunteers who
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Vare usually paid for their participation. Nursing attendants may observe
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Vfor
adverse effects and toxicity.
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3. A physician has ordered intramuscular (IM) injections of morphine, a
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narcotic, every 4 hours as needed for pain in a motor vehicle accident
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victim.The nursing attendant is aware this drug has a high abuse
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potential. Under what category would morphine be classified?
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A) Schedule I V




B) Schedule II V




C) Schedule III V




D) Schedule IV V




ACCURATE CHOICE:-
V B
Reasoning:->>>>>>

Narcotics with a high abuse potential are classified as Schedule II drugs
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because of severe dependence liability. Schedule I drugs have high abuse
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potential and no accepted medical use. Schedule III drugs have a lesser
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abuse potential than II and an accepted medical use. Schedule IV drugs
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havelow abuse potential and limited dependence liability.
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4. What concept is considered when generic drugs are substituted for
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brandname drugs?
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A) Bioavailability

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B) Critical concentration V




C) Distribution
D) Half-life
ACCURATE CHOICE:-AV




Reasoning:->>>>>>

Bioavailability is the portion of a dose of a drug that reaches the
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systemic circulation and is available to act on body cells. Binders used
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in a generic drug may not be the same as those used in the brand name
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drug. Therefore, the way the body breaks down and uses the drug may
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differ, which may eliminate a generic drug substitution. Critical
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concentration is the amount ofa drug that is needed to cause a
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therapeutic effect and should not differ between generic and brand name
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medications. Distribution is the phase of pharmacokinetics, which
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involves the movement of a drug to the bodys tissues and is the same in
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generic and brand name drugs. A drugs half-life isthe time it takes for
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the amount of drug to decrease to half the peak level, which should not
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change when substituting a generic medication.
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5. A nursing attendant is assessing the hospital clients home medication use. After
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listening to the hospital client list current medications, the nursing
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Vattendant askswhat priority question? V V V V




A) Do you take any generic medications?
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B) Are any of these medications orphan drugs?
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C) Are these medications safe to take during pregnancy?
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D) Do you take any over-the-counter medications?
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ACCURATE CHOICE:- V D
Reasoning:->>>>>>

It is important for the nursing attendant to specifically question use of
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Vover- the-counter medications because hospital clients may not consider
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Vthem important. The hospital client is unlikely to know the meaning of
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Vorphan drugs unless they too are primary health care providers. Safety
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Vduring pregnancy, use of a genericmedication, or classification of orphan
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Vdrugs are things the hospital client would be unable to answer but could
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Vbe found in reference books if the nursing attendant wishes to research
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Vthem.