RUBIN'S PATHOLOGY: CLIN
3 3
ICOPATHOLOGIC FOUNDATI 3
ONS OF MEDICINE3 3
7th Edition By David S. Strayer, Emanuel Rubin
3 3 3 3 3 3 3
3
,Test3Bank3Rubin's3Pathology:3Clinicopathologic3Foundations3of3Medicine37th3 Edition
Table3of3Contents:
Chapter31:3Cell3Adaptation,3Injury3and3Death
Chapter32:3Inflammation
Chapter33:3Repair,3Regeneration3and3Fibrosis
Chapter34:3Immunopathology
Chapter35:3Neoplasia
Chapter36:3Developmental3and3Genetic3Diseases
Chapter37:3Hemodynamic3Disorders
Chapter38:3Environmental3and3Nutritional3Pathology
Chapter39:3Infectious3and3Parasitic3Diseases
Section3II:3Pathogenesis3of3Systemic3Conditions3Expandable3section
Chapter310:3Aging
Chapter311:3Systemic3Autoimmune3Diseases
Chapter312:3Sepsis
Chapter313:3Obesity3and3Diabetes3Mellitus
Chapter314:3The3Pathology3of3Pregnancy
Chapter315:3The3Amyloidoses
Section3III:3Diseases3of3Individual3Organ3SystemsExpandable3section
Chapter316:3Blood3Vessels
Chapter317:3The3Heart
Chapter318:3The3Respiratory3System
Chapter319:3The3Gastrointestinal3Tract
Chapter320:3The3Liver3and3Biliary3System
Chapter321:3The3Pancreas
Chapter322:3The3Kidney
Chapter323:3The3Lower3Urinary3Tract3and3Male3Reproductive3System
Chapter324:3The3Female3Reproductive3System3and3Peritoneum
Chapter325:3The3Breast
Chapter326:3Hematopathology
Chapter327:3The3Endocrine3System
Chapter328:3The3Skin
Chapter329:3The3Head3and3Neck
Chapter330:3Bones,3Joints3and3Soft3Tissue
Chapter331:3Skeletal3Muscle3and3Peripheral3Nervous3System
Chapter332:3The3Central3Nervous3System
Chapter333:3The3Eye
Chapter334:3Forensic3Pathology
,Rubin's3Pathology:3Clinicopathologic3Foundations3of3Medicine3Chapt
er31:3Cell3Adaptation,3Injury3and3Death
Ischemia3and3other3toxic3injuries3increase3the3accumulation3of3intracellular3calcium3as3a3result
1. 3of:
A) release3of3stored3calcium3from3the3mitochondria.
B) improved3intracellular3volume3regulation.
C) decreased3influx3across3the3cell3membrane.
D) attraction3of3calcium3to3fatty3infiltrates.
The3patient3is3found3to3have3liver3disease,3resulting3in3the3removal3of3a3lobe3of3his3liver.3A
2. daptation3to3the3reduced3size3of3the3liver3leads3to3_ of3the3remaining3liver3cells.
A) metaplasia
B) organ3atrophy
C) compensatory3hyperplasia
D) physiologic3hypertrophy
A3person3eating3peanuts3starts3choking3and3collapses.3His3airway3obstruction3is3partiall
y3cleared,3but3he3remains3hypoxic3until3he3reaches3the3hospital.3The3prolonged3cell3hypo
3. xia3caused3a3cerebral3infarction3and3resulting _3in3the3brain.
A) caspase3activation
B) coagulation3necrosis
C) rapid3phagocytosis
D) protein3p533deficiency
Bacteria3and3viruses3cause3cell3damage3by
4. ,3which3is3unique3from3the3intracellula
r3damage3caused3by3other3injurious3agents.
A) disrupting3the3sodium/potassium3ATPase3pump
B) interrupting3oxidative3metabolism3processes
C) replicating3and3producing3continued3injury
D) decreasing3protein3synthesis3and3function
The3patient3has3a3prolonged3interruption3in3arterial3blood3flow3to3his3left3kidney,3causing3hypo
5. xic3cell3injury3and3the3release3of3free3radicals.3Free3radicals3damage3cells3by:
A) destroying3phospholipids3in3the3cell3membrane.
B) altering3the3immune3response3of3the3cell.
C) disrupting3calcium3storage3in3the3cell.
, D) inactivation3of3enzymes3and3mitochondria.
6. Injured3cells3have3impaired3flow3of3substances3through3the3cell3membrane3as3a3result3of:
A) increased3fat3load.
B) altered3permeability.
C) altered3glucose3utilization.
D) increased3surface3receptors.
7. Reversible3adaptive3intracellular3responses3are3initiated3by:
A) stimulus3overload.
B) genetic3mutations.
C) chemical3messengers.
D) mitochondrial3DNA.
8. Injured3cells3become3very3swollen3as3a3result3of:
A) increased3cell3protein3synthesis.
B) altered3cell3volume3regulation.
C) passive3entry3of3potassium3into3the3cell.
D) bleb3formation3in3the3plasma3membrane.
A3diabetic3patient3has3impaired3sensation,3circulation,3and3oxygenation3of3his3feet.3He3steps3o
n3a3piece3of3glass,3the3wound3does3not3heal,3and3the3area3tissue3becomes3necrotic.3The3necrot
9. ic3cell3death3is3characterized3by:
A) rapid3apoptosis.
B) cellular3rupture.
C) shrinkage3and3collapse.
D) chronic3inflammation.
A399-year-
10. old3woman3has3experienced3the3decline3of3cell3function3associated3with3age.3A3group3of3theo
ries3of3cellular3aging3focus3on3programmed:
A) changes3with3genetic3influences.
B) elimination3of3cell3receptor3sites.
C) insufficient3telomerase3enzyme.
D) DNA3mutation3or3faulty3repair.
An389-year-
old3female3patient3has3experienced3significant3decreases3in3her3mobility3and3stamina3during3
a33-
11. week3hospital3stay3for3the3treatment3of3a3femoral3head3fracture.3Which3of3the3following3phen
omena3most3likely3accounts3for3the3patients3decrease3in3muscle3function3that3underlies3her3r