questions & verified answers
naloxone - correct answer MOA: Pure opioid antagonist that competes and displaces opioids at
opioid receptor sites.
methadone, buprenorphine, buprenorphine+naloxone - correct answer Treatments for opioid use
disorder.
buprenorphine+naloxone - correct answer Treatment for opioid use disorder with comorbid pain.
opioids - correct answer Inappropriate use of what substance may be due to uncontrolled pain?
tablet, injectable, implant - correct answer Naltrexone delivery methods.
implant - correct answer Form of naltrexone limited to inpatient use.
buprenorphine - correct answer Mu receptor partial agonist for opioid withdrawal.
buprenorphine - correct answer Taking this medication too soon after last opioid use increases the
chances of intense withdrawal that comes on very quickly (precipitated withdrawal).
opioid intoxication - correct answer Symptoms include nausea and vomiting, respiratory
depression, constipation, itching, mioisis (small pupil). Patient will experience euphoria and sedation.
opioid withdrawal - correct answer Symptoms include N/V/D and dehydration, irritability,
restlessness, yawning, and twitching, increased HR/BP, chills, increased temperature, rhinorrhea,
lacrimation, dilated pupils.
, naloxone - correct answer Treatment for opioid intoxication during which cardiac or respiratory
depression is a concern.
cocaine intoxication - correct answer Symptoms include dilated pupils, HA, tremor, hyper-reflexia,
twitching, seizures, or coma, increased HR/BP, arrhythmias, and MI, N/V, incontinence/ARF, or
rhabdomyolysis
cocaine intoxication - correct answer Treatment includes BZD, antipsychotics, and management of
medical problems including HTN, stroke, cardiac arrhythmias, hyperthermia, and seizures.
cocaine - correct answer The use of beta blockers for treatment of chest pain and MI during this
intoxication is to be avoided due to unopposed a adrenergic stimulation.
alcohol intoxication - correct answer Signs vary with blood levels, from decreased reaction time,
muscle incoordination, ataxia, dysarthria, to respiratory failure and coma.
severe alcohol intoxication - correct answer Treatment includes cardiopulmonary function
maintenance, thiamine, and haloperidol PRN agitation.
thiamine - correct answer Given IM/IV for 3 days to prevent Wernicke's encephalopathy, along with
IV fluids and a banana bag.
benzodiazepines - correct answer Class of drugs to avoid for acute alcohol intoxication.
uncomplicated alcohol withdrawal - correct answer Treatment includes BZD in either symptom
triggered or fixed dose; diazepam and chlordiazepoxide have a longer half life, and oxazepam and
lorazepam are suitable for patients with hepatic dysfunction.
diazepam and chlordiazepoxide - correct answer BZDs with a long half-life used to treat AUD.