NR566 Final Exam 2025/2026 Exam
Questions and Verified Answers |
Already Graded A+
Naltrexone/Bupropion BB - 🧠 ANSWER ✔✔suicidal ideation-children,
adolescents and young adults
taking or discontinuing bupropion (Aplenzin, Budeprion, Bupropion,
Wellbutrin, and Zyban), severe neuropsychiatric reactions, including
depression, mania, psychosis, and homicidal ideation
H1 antagonists Adverse effects - 🧠 ANSWER ✔✔most common: sedation
dizzy, incoordination, confusional states, fatigue, paradoxical excitation
(insomnia, nervouseness, tremors, seizures)
,CNS stimulation: children + OD
GI (give with food)
anticholinergic: urinary hesitancy, constipation, palpitations
H1 antagonist Indication: drug selection - 🧠 ANSWER ✔✔sedating (h1) vs
non-sedations (h2)
H1 antagonist sleep aids - 🧠 ANSWER ✔✔every OTC sleep aid contains
H1 antagonist as active ingredient (diphenhydramine or pyrilamine)
H1 antagonists life span considerations: Infant - 🧠 ANSWER ✔✔-sedation
H1 antagonists 1st gen - 🧠 ANSWER ✔✔SEDATES
1st gen: Alkylamines (-pheniramine), Ethanolamines (clemastine,
diphenhydramine)
Phenothiazine (promethazine), Piperazine (hyroxyzine)
H1 antagonists life span considerations: Children/adolescents - 🧠 ANSWER
✔✔small doses
,Promethazine contraindicated <2
H1 antagonists life span considerations: pregnant - 🧠 ANSWER ✔✔avoid if
possible
H1 antagonists life span considerations: BF - 🧠 ANSWER ✔✔use with
caution
H1 antagonists life span considerations: older adults - 🧠 ANSWER
✔✔Beers criteria (avoid)
worsen glaucoma/BPH
small doses titrate if needed
H1 antagonists 2nd gen - 🧠 ANSWER ✔✔Non-sedate
Cetirizine, Levocetirizine, Fexofenadine, Loratadine, Desloratadine
Fexofenadine food-drug interactions - 🧠 ANSWER ✔✔fruit juices (4 hours
before or 1-2hours after)
Glucocorticoids MOA - 🧠 ANSWER ✔✔1. glucocorticoid receptors are
located inside the cell rather than on the cell surface
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED
3
, 2. glucocorticoids modulate the production of regulatory proteins rather
than the activity of signaling pathways.
*penetrate CM-bind w receptors cytoplasm- receptor inactive form to active
form- receptor steroid complex migrates to cell nucleus-bind to chromatin in
DNA- alter activity target gene.
Glucocorticoids pharmacologic effects - 🧠 ANSWER ✔✔anti-inflammatory
and immunosuppressive effects
metabolism and electrolytes: high dose= glucose rise, protein synthesis
suppressed, fat deposits mobilized
high dose= inhibit intestinal absorption of calcium
Glucocorticoids AE - 🧠 ANSWER ✔✔osteoporosis, infection, impaired
wound healing, hyperglycemia, myopathy, fluid/electrolyte disturbance,
growth delay, psych disturbances, cataracts/glaucoma, PUD, Iatrogenic
Cushing syndrome, adrenal suppression
Questions and Verified Answers |
Already Graded A+
Naltrexone/Bupropion BB - 🧠 ANSWER ✔✔suicidal ideation-children,
adolescents and young adults
taking or discontinuing bupropion (Aplenzin, Budeprion, Bupropion,
Wellbutrin, and Zyban), severe neuropsychiatric reactions, including
depression, mania, psychosis, and homicidal ideation
H1 antagonists Adverse effects - 🧠 ANSWER ✔✔most common: sedation
dizzy, incoordination, confusional states, fatigue, paradoxical excitation
(insomnia, nervouseness, tremors, seizures)
,CNS stimulation: children + OD
GI (give with food)
anticholinergic: urinary hesitancy, constipation, palpitations
H1 antagonist Indication: drug selection - 🧠 ANSWER ✔✔sedating (h1) vs
non-sedations (h2)
H1 antagonist sleep aids - 🧠 ANSWER ✔✔every OTC sleep aid contains
H1 antagonist as active ingredient (diphenhydramine or pyrilamine)
H1 antagonists life span considerations: Infant - 🧠 ANSWER ✔✔-sedation
H1 antagonists 1st gen - 🧠 ANSWER ✔✔SEDATES
1st gen: Alkylamines (-pheniramine), Ethanolamines (clemastine,
diphenhydramine)
Phenothiazine (promethazine), Piperazine (hyroxyzine)
H1 antagonists life span considerations: Children/adolescents - 🧠 ANSWER
✔✔small doses
,Promethazine contraindicated <2
H1 antagonists life span considerations: pregnant - 🧠 ANSWER ✔✔avoid if
possible
H1 antagonists life span considerations: BF - 🧠 ANSWER ✔✔use with
caution
H1 antagonists life span considerations: older adults - 🧠 ANSWER
✔✔Beers criteria (avoid)
worsen glaucoma/BPH
small doses titrate if needed
H1 antagonists 2nd gen - 🧠 ANSWER ✔✔Non-sedate
Cetirizine, Levocetirizine, Fexofenadine, Loratadine, Desloratadine
Fexofenadine food-drug interactions - 🧠 ANSWER ✔✔fruit juices (4 hours
before or 1-2hours after)
Glucocorticoids MOA - 🧠 ANSWER ✔✔1. glucocorticoid receptors are
located inside the cell rather than on the cell surface
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED
3
, 2. glucocorticoids modulate the production of regulatory proteins rather
than the activity of signaling pathways.
*penetrate CM-bind w receptors cytoplasm- receptor inactive form to active
form- receptor steroid complex migrates to cell nucleus-bind to chromatin in
DNA- alter activity target gene.
Glucocorticoids pharmacologic effects - 🧠 ANSWER ✔✔anti-inflammatory
and immunosuppressive effects
metabolism and electrolytes: high dose= glucose rise, protein synthesis
suppressed, fat deposits mobilized
high dose= inhibit intestinal absorption of calcium
Glucocorticoids AE - 🧠 ANSWER ✔✔osteoporosis, infection, impaired
wound healing, hyperglycemia, myopathy, fluid/electrolyte disturbance,
growth delay, psych disturbances, cataracts/glaucoma, PUD, Iatrogenic
Cushing syndrome, adrenal suppression
