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Exam (elaborations)

NURS 611 Exam 4 (95 Questions) – Renal, GI, Reproductive, Hepatic Disorders – Maryville University

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This document includes 95 expertly answered questions from Exam 4 of NURS 611: Advanced Pathophysiology for the 2025/2026 academic year at Maryville University. It is an extensive, high-yield study guide ideal for students preparing for advanced clinical exams in systems-based pathology, particularly focused on renal, gastrointestinal, hepatic, pancreatic, and reproductive systems. Topics include kidney physiology, glomerulonephritis, nephrotic syndrome, acute kidney injury (AKI), chronic renal insufficiency, electrolyte imbalances, and urinary tract infections (UTIs). The guide also explores pyelonephritis, interstitial cystitis, renal clearance measures (e.g., creatinine clearance, GFR, BUN), nephron structure, uromodulin (Tamm-Horsfall protein), and the renal implications of systemic disease. GI pathologies covered include GERD, bowel obstructions, peptic ulcer disease (PUD), dumping syndrome, Crohn’s disease, ulcerative colitis, and metabolic syndromes. The document also comprehensively addresses hepatitis A, B, C (phases and clinical signs), cirrhosis, portal hypertension, hepatic encephalopathy, and acute pancreatitis, detailing complications like SIRS and MODS. Reproductive and endocrine topics include PCOS, menstrual cycle physiology, ovarian cysts, dysmenorrhea, LH/FSH hormone actions, and follicular development. This document is particularly valuable for: Nurse Practitioner (NP) students MSN and DNP candidates Advanced Practice Registered Nurses (APRNs) Students in advanced renal, GI, hepatic, and reproductive pathophysiology courses Healthcare professionals preparing for certifying board exams or clinical rotations Keywords: renal physiology, nephrotic syndrome, glomerulonephritis, pyelonephritis, kidney injury, GFR, creatinine clearance, BUN, UTI, Tamm-Horsfall protein, metabolic syndrome, PUD, Crohn’s disease, ulcerative colitis, GERD, cirrhosis, hepatitis B, hepatic encephalopathy, portal hypertension, pancreatitis, PCOS, dysmenorrhea, LH, FSH, menstrual cycle, ovarian cysts, dumping syndrome, inflammation, reproductive pathophysiology, NURS 611, Maryville University

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Uploaded on
October 2, 2025
Number of pages
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Written in
2025/2026
Type
Exam (elaborations)
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Questions & answers

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Maryville NURS 611 Exam 4 2025/2026
Exam Questions and Correct Answers |
New Update



How much of the cardiac output do the kidneys require? - 🧠 ANSWER

✔✔20-25%


What causes the umbilical referred pain with kidney stones? - 🧠 ANSWER

✔✔sensory innervation of the upper part of the ureter arising from the 10th

thoracic nerve root.

What are the clinical manifestations of a UTI in older adults? - 🧠 ANSWER

✔✔confusion and poorly localized abdominal discomfort (symptoms are

vague).


What is pyelonephritis? - 🧠 ANSWER ✔✔it is an infection of one or both

upper urinary tracts(ureter, renal pelvis, and kidney interstitium).

,What are the underlying risk factors for the development of pyelonephritis?

- 🧠 ANSWER ✔✔urinary obstruction and reflux of urine from the bladder

(vesicoureteral reflux).

What microorganisms are associated with acute pyelonephritis? - 🧠

ANSWER ✔✔e. coli, proteus, or pseudomonas.


What do the microorganisms that cause pyelonephritis do to increase the

risk of stone formation? - 🧠 ANSWER ✔✔the microorganisms split urea into

ammonia, making alkaline urine that increases the risk.


Define painful bladder syndrome (interstitial cystitis). - 🧠 ANSWER ✔✔it is a

condition that includes nonbacterial infectious cystitis and noninfectious

cystitis.

It is possible that noninfectious cystitis is caused by an autoimmune

response. What happens during an autoimmune reaction? - 🧠 ANSWER

✔✔it may be responsible for inflammatory response, which includes mast

cell activation, altered epithelial permeability, neuroinflammation, and

increased sensory nerve stimulation.

How is a diagnosis of IC differentiated from a diagnosis of pyelonephritis? -

🧠 ANSWER ✔✔urine culture, urinalysis, and clinical signs and symptoms.

, White blood cell casts indicate pyelonephritis, but they are not always

present in the urine.


What lab values point to a reduced GFR? - 🧠 ANSWER ✔✔elevated

plasma urea, creatinine concentration, or reduced renal creatinine

clearance.


What is acute glomerulonephritis? - 🧠 ANSWER ✔✔it is a term that

includes renal diseases that cause glomerular inflammation through

immune mechanisms.

What happens to the GFR during an inflammatory response? - 🧠 ANSWER

✔✔the glomerular capillary filtration membrane including the endothelium,

basement membrane, and epithelium (podocytes) are damaged by

inflammation causing immune mechanisms.

What are the classic symptoms of acute glomerulonephritis? - 🧠 ANSWER

✔✔sudden onset of hematuria including red blood cell casts and

proteinuria (milder than nephrotic syndrome), and in more severe cases,

these symptoms are also accompanied by edema, hypertension, and

impaired renal function.




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