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NURS 611 Exam 1 (85 Questions) – Pathophysiology, Genetics, Neuro, Fluid Balance – Maryville University

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This document contains a complete set of 85 accurately answered questions for Exam 1 in NURS 611: Advanced Pathophysiology, tailored for the 2025/2026 academic year. It serves as a comprehensive study resource covering a wide range of high-yield topics essential for advanced nursing and healthcare education. Core subjects include cellular function, organelle roles, membrane dynamics, fluid and electrolyte regulation, osmosis, and oncotic vs hydrostatic pressure. The material explains protein synthesis, osmolality between ICF/ECF, and types of membrane transport such as diffusion, facilitated diffusion, and active transport, as well as the impact of various IV fluid types on cellular behavior. Genetic and epigenetic concepts are thoroughly reviewed, including mutation types, chromosomal abnormalities, gene expression, DNA methylation, and conditions like Down syndrome, Turner syndrome, and Klinefelter's syndrome. The document also delves into neurophysiology, exploring action potentials, neurotransmitters, seizures, CVAs, neurodegenerative disorders (e.g., Parkinson’s, MS, Myasthenia Gravis), and more. Students will benefit from concise comparisons (e.g., apoptosis vs necrosis, ischemia vs hypoxia, physiologic vs pathologic cellular changes) and practical clinical insights that align with current nursing curricula and board preparation standards. This resource is ideal for: Nurse Practitioner (NP) students MSN and DNP candidates Advanced Practice Registered Nurses (APRNs) Students in graduate pathophysiology or related healthcare programs Individuals preparing for certification exams in clinical or academic settings Keywords: pathophysiology, NURS 611, cellular function, fluid balance, osmolality, membrane transport, action potential, resting potential, neurotransmitters, seizures, CVA types, epigenetics, gene expression, mutations, apoptosis, necrosis, ischemia, hypoxia, genetic disorders, Down syndrome, Klinefelter, Turner syndrome, advanced nursing, exam prep, nurse practitioner, neurophysiology, Maryville University

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Uploaded on
October 2, 2025
Number of pages
37
Written in
2025/2026
Type
Exam (elaborations)
Contains
Questions & answers

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Maryville NURS 611 Exam 1 2025/2026
Exam Questions with 100% Correct
Answers | Latest Update



Nucleus - 🧠 ANSWER ✔✔DNA and RNA are housed here. Contains all

genetic material.


Ribosomes - 🧠 ANSWER ✔✔Responsible for protein synthesis


Mitochondria - 🧠 ANSWER ✔✔Produces ATP. This structure generates

ATP by oxidative phosphorylation. Cells power plant. The more a cell

needs energy the more it will need this. The heart would need more of this

than the eyes, bones, or skin.


Golgi apparatus - 🧠 ANSWER ✔✔Responsible for packaging and

distribution. Processes and packages proteins for delivery. Shipping and

receiving center. Receives newly synthesized proteins and lipids from the

ER. Modified with sugar molecules for their destination. Then sends them

on their way.

,Lysosome - 🧠 ANSWER ✔✔Degrades and recycles waste. Contains

digestive enzymes. Does this with hydrolase enzymes


Peroxisome - 🧠 ANSWER ✔✔Has a byproduct of H2O2 which produces

Free Radicals. Can detoxify compounds and fatty acids. (Think peroxide)

they break things down using oxygen. Byproduct is H2O2 (hydrogen

peroxide). Digest and breakdown organic molecules - uses molecular

oxygen.


Free Radical - 🧠 ANSWER ✔✔Any molecular species capable of

independent existence that contains a single unpaired electron in an outer

orbit. Having one unpaired electron makes the molecule unstable; the

molecule becomes stabilized either by donating or by accepting an electron

from another molecule.


Reactive Oxygen Species (ROS) - 🧠 ANSWER ✔✔Chemically reactive

molecules from molecular oxygen formed as natural oxidant species in

cells during mitochondrial respiration and energy generation.


Damage by free radicals/ROS - 🧠 ANSWER ✔✔When excessive ROSs

overwhelm the endogenous antioxidant systems, oxidative stress occurs. A

,very large excess of ROS tends to cause necrosis, but smaller excess of

ROS can cause apoptosis.

Free radicals can cause lipid peroxidation or the destruction of unsaturated

fatty acid, alterations of proteins, and alterations in DNA


What is the plasma membrane made up of? - 🧠 ANSWER ✔✔Lipids,

proteins, and polysaccharides


Why do we need a cell membrane? - 🧠 ANSWER ✔✔To keep the ICF and

ECF separate, structure, protection, activation of cell, transport, and cell-to-

cell interaction


How is osmolality different between ICF and ECF? - 🧠 ANSWER ✔✔The

osmolality of ICF and ECF tends to equalize and therefore provides a

measure of body fluid concentration and thus the body's hydration status.


What do proteins do for the cell? - 🧠 ANSWER ✔✔Proteins act as


Recognition and binding units (receptors) for substances moving in and out

of the cell;

Pores or transport channels for various electrically charged particles called

ions or electrolytes and specific carriers for amino acids and

monosaccharides;

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, Specific enzymes that drive active pumps that promote concentration of

certain ions, particularly potassium (K+), within the cell while keeping

concentrations of other ions, for example sodium (Na+), below

concentrations found in the extracellular environment;

Cell surface markers, such as glycoproteins (proteins attached to

carbohydrates), that identify a cell to its neighbor;

Cell adhesion molecules (CAMs), or proteins that allow cells to hook

together and form attachments to the cytoskeleton for maintaining cellular

shape; and

Catalysts of chemical reactions, for example, conversion of lactose to

glucose.

How much of the cell membrane is made up of protein? - 🧠 ANSWER

✔✔55% the cell membrane is made up of protein


What is a protein? - 🧠 ANSWER ✔✔A protein is made from a chain of

amino acids, known as polypeptides. There are 20 types of amino acids in

proteins, and each type of protein has a unique sequence of amino acids.

Proteins are the major workhorses of the cell.

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