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Evolutionary Analysis 5th Edition by Herron Jon; Freeman Scott ISBN 9780321998378
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Chapter 1-20
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Chapter 1 A Case for Evolutionary
w w w w w Thinking: Understanding HIV
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1) In which of the following regions has AIDS killed the largest number of
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individuals?
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A) India
B) Sub-Saharan Africa w
C) United States w
D) China
E) United Kingdom w
wAnswer: B w
wSection: 1.1
Skill: Knowledge/Comprehension
2) The HIV virus contains all of the following components
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A) integrase
B) double-stranded RNA w
C) single-stranded RNA w
D) reverse transcriptase w
E) protease
wAnswer:
B Section:
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1.1
Skill: Knowledge/Comprehension
3) The acronym HIV stands for which of the following?
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A) human intercellular virus w w
B) human immune virus w w
C) human immunodeficiency virus
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D) human immunity virus w w
E) human immunodeficiency vector
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wAnswer: C
Section: 1.1
Skill: Knowledge/Comprehension
4) Which of the following enzymes is responsible for transcribing viral RNA into
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DNA?
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A) RNA polymerase w
B) reverse transcriptase w
C) DNA polymerase w
D) reverse integrase w
E) RNA duplicase w
wAnswer: B w
wSection: 1.1
2
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,Skill: Knowledge/Comprehension
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Copyright © 2014 Pearson
, 5) The proteins that enable the HIV virus to bind to cells are typically
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CD4 and CCR5. On what type of cells are these proteins typically
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observed?
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A) plasma cells w
B) dendritic cells w
C) effector helper T cells w w w
D) memory helper T cells w w w
E) both C and w w
D Answer:
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E Section:
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1.1
Skill: Knowledge/Comprehension
6) The AIDS phase of HIV infection begins when the concentration of CD4 T
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cells in the blood drops below what concentration?
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A) 2,000 cells per cubic millimeter
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B) 1,000 cells per cubic millimeter
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C) 500 cells per cubic millimeter
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D) 200 cells per cubic millimeter
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E) No CD4 T cells are
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wobserved. Answer: D w w
wSection: 1.1 w
Skill: Knowledge/Comprehension
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7) Which of the following drug categories are used to treat HIV infections?
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A) integrase inhibitors w
B) protease inhibitors w
C) reverse transcriptase inhibitors w w
D) DNAse inhibitors w
E) fusion inhibitors w
Answer: D
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Section: 1.2
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Skill: Knowledge/Comprehension
8) Coreceptor inhibitors block HIV infection by preventing which of the following?
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A) binding of the HIV virion onto the plasma membrane
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B) binding of the HIV virion onto the CCR5 receptor
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C) binding of the HIV virion onto the gp120 protein
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D) degrading the coreceptor so the virion cannot attach
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E) binding of the HIV virion onto the
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w CD4 receptor Answer: B
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Section: 1.2
Skill: Application/Analysis
9) What is the effect of the ∆32 allele of CCR5 on HIV binding?
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A) appears on the surface of CD4 T cells, but the HIV virion is unable to
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infect the host cell
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