MULTIPLE CHOICE OF QUESTIONS AND
DETAILED SOLVED SOLUTIONS
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What is the method of action of salicylates? - CORRECT ANSWER-
Inhibit synthesis of prostaglandin and inhibit platelet
aggregation
What is aspirin indicated for? - CORRECT ANSWER-Treatment of
mild to moderate pain
Fever
Some inflammatory conditions
Where is aspirin absorbed? - CORRECT ANSWER-Stomach
What is the purpose of enteric coated aspirin? - CORRECT ANSWER-
Aspirin is absorbed in the stomach, but it is very irritating. EC
aspirin prevents stomach irritation/bleeding by allowing the
aspirin to be absorbed in the intestines.
What allergies contraindicates the use of aspirin? - CORRECT
ANSWER-Allergy to salicylates, NSAIDs, or tartrazine
,What antiinflammatory drug is contraindicated for use in
children? - CORRECT ANSWER-Aspirin
Why should children not receive aspirin? - CORRECT ANSWER-
Increases the risk of Reye syndrome
A patient has a surgery scheduled in 1 week. What medication
should the nurse advise the patient not to take? - CORRECT ANSWER-
Aspirin
What occurs if a patient takes high levels of aspirin? - CORRECT
ANSWER-Salicylism
What are the differences between salicylism and salicylate
toxicity? - CORRECT ANSWER-Salicylism- Dizziness, tinnitus,
difficulty hearing, n/v/d, and confusion
Salicylate Toxicity- Hyperpnea, tachypnea, hemorrhage,
excitement, pulmonary edema, convulsions, metabolic acidosis,
and coma
A patient presents with metabolic acidosis, high RR, tachypnea,
and agitation. What is the patient experiencing? - CORRECT
ANSWER-Salicylate toxicity
If an adult is given 20-25 g of a salicylate in one dose, what are
they at risk of developing? - CORRECT ANSWER-Salicylate toxicity
, If a child is given 4 g of a salicylate in one dose, what are they at
risk of developing? - CORRECT ANSWER-Salicylate toxicity
How should aspirin be administered? - CORRECT ANSWER-With food
to reduce GI distress
What organ function will we monitor for a patient on aspirin? -
CORRECT ANSWER-Renal function
What are the properties of NSAIDs? - CORRECT ANSWER-analgesic,
anti-inflammatory, antipyretic
NSAIDs have a black box warning for what? - CORRECT ANSWER-
The increased risk of CV events and GI bleeding
What is the method of action for NSAIDs? - CORRECT ANSWER-
Block COX enzymes
Where is COX-1 found? - CORRECT ANSWER-all tissues
Where is COX 2 found? - CORRECT ANSWER-Only in
inflamed/damaged tissue
Which COX enzyme functions to maintain renal function,
maintain gastric mucosa integrity, and increases hemostasis? -
CORRECT ANSWER-COX-1