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For quick relief of Anxiety - 🧠 ANSWER ✔✔2 wk course of intermediate
acting benzodiazepine PRN Q 8 hrs.
Buspirone (BuSpar) - 🧠 ANSWER ✔✔o Not habit forming
o Not a CNS depressant
o MOA
• Mostly unknown
• High affinity for serotonin & lesser affinity for dopamine receptors
Hydroxyzine (Atarax, Vistaril) - 🧠 ANSWER ✔✔o No abuse or addiction
concerns
o Strong antihistamine
,• Anticholinergic effects
Performance anxiety - 🧠 ANSWER ✔✔o Beta-blocker
• Taken an hour before can help decrease symptoms without causing
sedation.
• Propranolol (Inderal)
• Atenolol (Tenormin)
Info about Benzodiazepines - 🧠 ANSWER ✔✔o PRESCRIBE cautiously &
for as short a time as possible!!
o Scheduled IV
o Low abuse when used short term
o Routine daily use may lead to dependence
o Quick relief for anxiety
DO NOT STOP abruptly
• Can cause seizures
• Discontinue over many weeks
Benzodiazepine MOA - 🧠 ANSWER ✔✔• Rapid onset
,• Those with fastest onset are associated w/ abuse
• Metabolized in liver & CYP450
• Use caution if alcohol or drug use is suspected
CNS effects
• Sedation
• Decreased anxiety
• Muscle relaxation
• Anti-convulsant action
Diazepam (valium) - 🧠 ANSWER ✔✔• Long half life
• Effective in reducing spasm & decrease seizure activity
Alprazolam (Xanax) - 🧠 ANSWER ✔✔• Works quickly
• Moderate half-life
• Rapid relief of symptoms
• Most addictive
Lorazepam (Ativan) - 🧠 ANSWER ✔✔• Used for anxiety
• Slow onset
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, • Shorter half-life
SSRIs - 🧠 ANSWER ✔✔o Many types of anxiety disorders
• PTSD
• OCD
• Panic attacks
• Social anxiety
o Paroxetine (paxil)
Medications for Anxiety - 🧠 ANSWER ✔✔Benzodiazepines
SSRIs
SNRIs
Others... hydroxyzine, propranolol etc.
Info for insomnia - 🧠 ANSWER ✔✔•Challenge to promote sleep & avoid
dependency on meds
•Essential to rule out other causes
o Pain
o Sleep apnea