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College aantekeningen Mechanismen van ziekte inflammatie en immunopathologie histologie

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College aantekeningen Mechanismen van ziekte inflammatie en immunopathologie histologie Immuunrespons op auto-antigenen Auto-immuunziekten Pathogenese van auto-immuunziekten: algemeen T cel gemedieerd Coeliakie Innate immune response IBD

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Uploaded on
September 22, 2025
Number of pages
25
Written in
2022/2023
Type
Class notes
Professor(s)
Ferdinand
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Deel II : Inflammatie en
immunopathologie

,Deel II: Inflammatie en
immunopathologie
Immuunrespons op auto-antigenen
Auto-immuunziekten
Pathogenese van auto-immuunziekten: algemeen
T cel gemedieerd
Coeliakie
Innate immune response
IBD

, INFLAMMATIE
• Protectieve respons
• Soms schadelijk ipv nuttig
• Complexe reactie van vnl. bloedvaten en leukocyten in
respons op inflammatoire mediatoren
• Oorzaken:
– Infecties en microbiële toxines
• Cfr. opleidingsonderdeel ‘Infecties en afweer’
– Necrose tgv ischemie, trauma of fysische of chemische schade
• Vb. myocardinfarct
– Vreemd materiaal, endogeen of exogeen toxisch agens
• Vb. slikpneumonie
– Immuun-gemedieerde inflammatoire aandoeningen,
autoimmuunziekten, immuunreacties
• Vb. ziekte van Crohn, astma
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