, Chapter 1, The Foundation of Pharmacology: Quality and Safety
q q q q q q q q
1. A woman diagnosed with obsessive–
q q q q
compulsive disorder has been prescribed oral paroxetine hydrochloride. What is the
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expected effect for this prescription?
q q q q
A. Curative effect on symptoms q q q
B. Systemic effect on symptoms q q q
C. Local effect on symptoms q q q
D. Parenteral effect on symptoms q q q
ANS: B q
Rationale: Drugs that produce systemic effects are taken into the body, circulated through the b
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loodstream to their sites of action in various body tissues, and eventually eliminated from the b
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ody. Curative agents are given to cure a disease process. In this case, paroxetine hydrochloride
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will control the symptoms but not cure the disorder. Drugs with local effects, such as sunscreen
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and local anesthetics, act mainly at the site of application. Paroxetine hydrochloride is not adm
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inistered parenterally. Parenteral agents are administered subcutaneously, intramuscularly, or
q q q q q q q q q
intravenously.
PTS: 1 REF: p. 3, Introduction OBJ: 1 q q
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
q q q q q q q q q
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety q q q q q q q q
KEY: Integrated Process: Nursing Process
q q q q
BLM: Cognitive Level: Understand NOT: Multiple Choice
GRADESBOOST.COM
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2. A client has been prescribed an antibiotic. This medication is a naturally occurring
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substance that has been cheG
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edication?
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A. Synthetic drug q
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B. Semisynthetic drug
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C. Biotechnology drug q
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D. Prototype drug q
q
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ANS: B q
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Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances that
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have been chemically modified. Synthetic drugs are more standardized in their chemical charac
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teristics, more consistent in their effects, and less likely to produce allergic reactions. Biotechn
q q q q q q q q q q q q q
ology drugs involve manipulating DNA and RNA and recombining genes into hybrid molecul
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es that can be inserted into living organisms. Prototype drugs are the first drug of a particular gr
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oup to be developed.
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PTS: 1 REF: p. 3, Drug Sources OBJ: 1 q q q
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
q q q q q q q q q
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety q q q q q q q q
KEY: Integrated Process: Nursing Process
q q q q
BLM: Cognitive Level: Understand
q NOT: Multiple Choice q q q q
3. Which classification applies to morphine?
q q q q
A. Central nervous system depressant q q q
B. Central nervous system stimulant q q q
, C. Anti-inflammatory
D. Antihypertensive
ANS: A q
Rationale: Drugs are classified according to their effects on particular body systems, their ther
q q q q q q q q q q q q q
apeutic uses, and their chemical characteristics. Morphine is classified as a central nervous sys
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tem depressant and will produce this effect in the client. A central nervous system stimulant inc
q q q q q q q q q q q q q q q
reases attention and raises mood. An anti-
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inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An antih
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ypertensive agent reduces blood pressure. q q q q
PTS: 1 REF:
p. 3, Drug Classifications and Prototypes OBJ:
q q 1 q q q q
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
q q q q q q q q q
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety q q q q q q q q
KEY: Integrated Process: Nursing Process
q q q q
BLM: Cognitive Level: Remember
q NOT: Multiple Choice q q q q
4. A client is administered amoxicillin. The generic name of this medication belongs to which dr
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ug group?
q
A. Selective serotonin reuptake inhibitors q q q
B. Diuretics
C. Penicillins
D. ACE inhibitors q
GRADESBOOST.COM
q
ANS: C q
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Rationale: The generic nameGRADESBOOST.COM
often indicates the drug group (e.g., drugs with generic names en
q
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ding in ―cillin‖ are penicillins). Selective serotonin reuptake inhibitors are medications that ha
q
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ve antidepressant effects; SSRI is a broad classification, not a generic name. Diuretics are medi
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cations that increase urine output; diuretic is a broad classification, not a generic name. ACE in
q
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hibitor is the broad classification for the angiotensin receptor blockers, not the generic name.
q
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PTS: 1 REF: p. 3, Drug Names OBJ: 2 q q q
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NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
q
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OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
q
q q q q q q q q
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KEY: Integrated Process: Nursing Process
q q q q
BLM: Cognitive Level: Understand
q NOT: Multiple Choice q q q q
5. The administration of diphenhydramine is regulated by which U.S. government agency?
q q q q q q q q q q
A. Public Health Service q q
B. Federal Trade Commission q q
C. Occupational Safety and Health Administration q q q q
D. Food and Drug Administration q q q q
ANS: D q
, Rationale: The Food and Drug Administration approves drugs for over-the-
q q q q q q q q q
counter availability, including the transfer of drugs from prescription to OTC status, and may r
q q q q q q q q q q q q q q
equire clinical trials to determine the safety and effectiveness of OTC use. The Public Health
q q q q q q q q q q q q q q q
Service is regulated by the state to maintain the health of individual citizens of the state. The F
q q q q q q q q q q q q q q q q q
ederal Trade Commission regulates imports and exports throughout the nation. The Occupatio
q q q q q q q q q q q
nal Safety and Health Administration regulates safety within the workplace.
q q q q q q q q q
PTS: 1 REF:
p. 4, Prescription and Nonprescription Drugs OBJ: 4
q q q q q q
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
q q q q q q q q q
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety q q q q q q q q
KEY: Integrated Process: Nursing Process
q q q q
BLM: Cognitive Level: Understand
q NOT: Multiple Choice q q q q
6. In the U.S., the administration of anabolic steroids is regulated by which law?
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A. The Food, Drug, and Cosmetic Act of 1938
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B. The Comprehensive Drug Abuse Prevention and Control Act
q q q q q q q
C. The Harrison Narcotic Act q q q
D. The Sherley Amendment q q
ANS: B q
Rationale: The Comprehensive Drug Abuse Prevention and Control Act regulates the manufac
q q q q q q q q q q q
ture and distribution of narcotics, stimulants, depressants, hallucinogens, and anabolic steroids
q q q q q q q q q q
. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA powers and responsi
q q q q q q q q q q q q q q q
GRADESBOOST.COM
bilities, giving the FDA control over drug safety. The Harrison Narcotic Act restricted the impo
q
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rtation, manufacture, sale, and use of opium, cocaine, marijuana, and other drugs that the act d e
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ectiveness.
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q
q
PTS: 1 REF:
q
p. 4, Prescription and Nonprescription Drugs OBJ: 3
q q q q q q
q
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
q
q q q q q q q q q
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
q
q q q q q q q q
q
KEY: Integrated Process: Nursing Process
q q q q
q
BLM: Cognitive Level: Remember
q NOT: Multiple Choice q q q q
q
7. A nurse is responsible for maintaining an accurate count and record of the controlled substa
q q q q q q q q q q q q q q
nces on the nursing division. This nursing action is regulated by which U.S. law or agency?
q q q q q q q q q q q q q q q
A. The Food, Drug, and Cosmetic Act of 1938
q q q q q q q
B. The Public Health Service q q q
C. The Drug Enforcement Administration
q q q
D. The Sherley Amendment q q q
ANS: C q
q q q q q q q q
1. A woman diagnosed with obsessive–
q q q q
compulsive disorder has been prescribed oral paroxetine hydrochloride. What is the
q q q q q q q q q q q
expected effect for this prescription?
q q q q
A. Curative effect on symptoms q q q
B. Systemic effect on symptoms q q q
C. Local effect on symptoms q q q
D. Parenteral effect on symptoms q q q
ANS: B q
Rationale: Drugs that produce systemic effects are taken into the body, circulated through the b
q q q q q q q q q q q q q q
loodstream to their sites of action in various body tissues, and eventually eliminated from the b
q q q q q q q q q q q q q q q
ody. Curative agents are given to cure a disease process. In this case, paroxetine hydrochloride
q q q q q q q q q q q q q q q
will control the symptoms but not cure the disorder. Drugs with local effects, such as sunscreen
q q q q q q q q q q q q q q q q
and local anesthetics, act mainly at the site of application. Paroxetine hydrochloride is not adm
q q q q q q q q q q q q q q
inistered parenterally. Parenteral agents are administered subcutaneously, intramuscularly, or
q q q q q q q q q
intravenously.
PTS: 1 REF: p. 3, Introduction OBJ: 1 q q
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
q q q q q q q q q
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety q q q q q q q q
KEY: Integrated Process: Nursing Process
q q q q
BLM: Cognitive Level: Understand NOT: Multiple Choice
GRADESBOOST.COM
q q q q q
q
q
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
q
q q q q q q q q q q q q
q
substance that has been cheG
mRicA
alDlyEm
SoBdOifOieSd.TW
q haOt Mi s another name for this type of m
.C q q q q q q q q q q q
q
edication?
q
A. Synthetic drug q
q
B. Semisynthetic drug
q
q
q
C. Biotechnology drug q
q
D. Prototype drug q
q
q
ANS: B q
q
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances that
q
q q q q q q q q q q q
have been chemically modified. Synthetic drugs are more standardized in their chemical charac
q q q q q q q q q q q q
teristics, more consistent in their effects, and less likely to produce allergic reactions. Biotechn
q q q q q q q q q q q q q
ology drugs involve manipulating DNA and RNA and recombining genes into hybrid molecul
q q q q q q q q q q q q
es that can be inserted into living organisms. Prototype drugs are the first drug of a particular gr
q q q q q q q q q q q q q q q q q
oup to be developed.
q q q
PTS: 1 REF: p. 3, Drug Sources OBJ: 1 q q q
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
q q q q q q q q q
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety q q q q q q q q
KEY: Integrated Process: Nursing Process
q q q q
BLM: Cognitive Level: Understand
q NOT: Multiple Choice q q q q
3. Which classification applies to morphine?
q q q q
A. Central nervous system depressant q q q
B. Central nervous system stimulant q q q
, C. Anti-inflammatory
D. Antihypertensive
ANS: A q
Rationale: Drugs are classified according to their effects on particular body systems, their ther
q q q q q q q q q q q q q
apeutic uses, and their chemical characteristics. Morphine is classified as a central nervous sys
q q q q q q q q q q q q q
tem depressant and will produce this effect in the client. A central nervous system stimulant inc
q q q q q q q q q q q q q q q
reases attention and raises mood. An anti-
q q q q q q
inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An antih
q q q q q q q q q q q q q
ypertensive agent reduces blood pressure. q q q q
PTS: 1 REF:
p. 3, Drug Classifications and Prototypes OBJ:
q q 1 q q q q
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
q q q q q q q q q
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety q q q q q q q q
KEY: Integrated Process: Nursing Process
q q q q
BLM: Cognitive Level: Remember
q NOT: Multiple Choice q q q q
4. A client is administered amoxicillin. The generic name of this medication belongs to which dr
q q q q q q q q q q q q q q
ug group?
q
A. Selective serotonin reuptake inhibitors q q q
B. Diuretics
C. Penicillins
D. ACE inhibitors q
GRADESBOOST.COM
q
ANS: C q
q
Rationale: The generic nameGRADESBOOST.COM
often indicates the drug group (e.g., drugs with generic names en
q
q q q q q q q q q q q q q q
ding in ―cillin‖ are penicillins). Selective serotonin reuptake inhibitors are medications that ha
q
q q q q q q q q q q q q
q
ve antidepressant effects; SSRI is a broad classification, not a generic name. Diuretics are medi
q q q q q q q q q q q q q q
q
cations that increase urine output; diuretic is a broad classification, not a generic name. ACE in
q
q q q q q q q q q q q q q q q
hibitor is the broad classification for the angiotensin receptor blockers, not the generic name.
q
q q q q q q q q q q q q q
q
q
PTS: 1 REF: p. 3, Drug Names OBJ: 2 q q q
q
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
q
q q q q q q q q q
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
q
q q q q q q q q
q
KEY: Integrated Process: Nursing Process
q q q q
BLM: Cognitive Level: Understand
q NOT: Multiple Choice q q q q
5. The administration of diphenhydramine is regulated by which U.S. government agency?
q q q q q q q q q q
A. Public Health Service q q
B. Federal Trade Commission q q
C. Occupational Safety and Health Administration q q q q
D. Food and Drug Administration q q q q
ANS: D q
, Rationale: The Food and Drug Administration approves drugs for over-the-
q q q q q q q q q
counter availability, including the transfer of drugs from prescription to OTC status, and may r
q q q q q q q q q q q q q q
equire clinical trials to determine the safety and effectiveness of OTC use. The Public Health
q q q q q q q q q q q q q q q
Service is regulated by the state to maintain the health of individual citizens of the state. The F
q q q q q q q q q q q q q q q q q
ederal Trade Commission regulates imports and exports throughout the nation. The Occupatio
q q q q q q q q q q q
nal Safety and Health Administration regulates safety within the workplace.
q q q q q q q q q
PTS: 1 REF:
p. 4, Prescription and Nonprescription Drugs OBJ: 4
q q q q q q
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
q q q q q q q q q
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety q q q q q q q q
KEY: Integrated Process: Nursing Process
q q q q
BLM: Cognitive Level: Understand
q NOT: Multiple Choice q q q q
6. In the U.S., the administration of anabolic steroids is regulated by which law?
q q q q q q q q q q q q
A. The Food, Drug, and Cosmetic Act of 1938
q q q q q q q
B. The Comprehensive Drug Abuse Prevention and Control Act
q q q q q q q
C. The Harrison Narcotic Act q q q
D. The Sherley Amendment q q
ANS: B q
Rationale: The Comprehensive Drug Abuse Prevention and Control Act regulates the manufac
q q q q q q q q q q q
ture and distribution of narcotics, stimulants, depressants, hallucinogens, and anabolic steroids
q q q q q q q q q q
. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA powers and responsi
q q q q q q q q q q q q q q q
GRADESBOOST.COM
bilities, giving the FDA control over drug safety. The Harrison Narcotic Act restricted the impo
q
q q q q q q q q q q q q q q
rtation, manufacture, sale, and use of opium, cocaine, marijuana, and other drugs that the act d e
q
q q q q q q q q q q q q q q q
f i Gn eRd Aa Ds E
naSrcBoO
tiO
csSTh.eCSOhM
q
.T erley Amendment of 1912 prohibited fraudulent claims of drug eff
q q q q q q q q q q q
q
ectiveness.
q
q
q
PTS: 1 REF:
q
p. 4, Prescription and Nonprescription Drugs OBJ: 3
q q q q q q
q
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies T
q
q q q q q q q q q
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
q
q q q q q q q q
q
KEY: Integrated Process: Nursing Process
q q q q
q
BLM: Cognitive Level: Remember
q NOT: Multiple Choice q q q q
q
7. A nurse is responsible for maintaining an accurate count and record of the controlled substa
q q q q q q q q q q q q q q
nces on the nursing division. This nursing action is regulated by which U.S. law or agency?
q q q q q q q q q q q q q q q
A. The Food, Drug, and Cosmetic Act of 1938
q q q q q q q
B. The Public Health Service q q q
C. The Drug Enforcement Administration
q q q
D. The Sherley Amendment q q q
ANS: C q
