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Name at least 3 abnormalities on bloodwork you would expect to see in
a dog with cushings disease ---------CORRECT ANSWER-----------------1
stress leukogram
2 elevated PCV
3 elevated ALP
4 elevated cholesterol
5 elevated glucose
6 low BUN
7 low USG
What is the most common cause of cushing disease in dogs ---------
CORRECT ANSWER-----------------85% pituitary dependent (pituitary
gland adenoma)
15 % adrenal gland hyperplasia (50/50 benign/ malignant)
,Low dose dex diagnostic shows that cushing's is pituitary dependent if
(low/high) at 4 hours and (low/high) at 8 hours ---------CORRECT
ANSWER-----------------low at 4 hours
high at 8 hours
Name at least 3 blood work abnormalities consistent with addison's
disease ---------CORRECT ANSWER-----------------1 Na:K < 27
2 elevated calcium
3 low chloride
4 low glucose
5 low USG
What is the most common cause of addison's disease ---------CORRECT
ANSWER-----------------1 primary adrenal problem- idiopathic/ immune
mediated attack of adrenals
2 pituitary ACTH deficiency- iatrogenic
What are 3 bloodwork abnormalities seen with hypothyroidism ---------
CORRECT ANSWER-----------------1 hypercholesterolemia
2 elevated CL
,3 non regenerative anemia
How is hypothyroidism diagnosed ---------CORRECT ANSWER----------------
-High TSH, Low T4 and T3
Total T4 screening- low resting levels
Free T4 by electrodialysis
TSH stim test- non responsive T3/T4, high TSH
What is the most common cause of hypothyroidism ---------CORRECT
ANSWER-----------------1 95% thyroid problem (idiopathic atrophy)
2 pituitary problem- no TSH
3 hypothalamic- no TRH
A dog presents with a history of PUPD and nocturia. owners are very
sure this is not behavioral. there is no glycosuria and no azotemia. CBC
chem UA are normal aside from a USG of 1.006. what is your top
differential and what diagnostic test would you run ---------CORRECT
ANSWER-----------------diabetes insipidus
water deprivation test- only psychogenic can concentrate
, water + ADH- central concentrates
gradual water deprivation- medullary wash out
What are at least 2 possible causes of diabetes inspidus ---------
CORRECT ANSWER-----------------1 nephrogenic DI- inability of renal
tubules to respond to ADH
2 central pituitary DI- problem with ADH release
3 central hypothalamus DI-problem with ADH vasopressin production
4 psychogenic- excessive water intake, disorder of thurst centers
Production/ release of vasopressin is controlled by serum ____ and
blood volume ---------CORRECT ANSWER-----------------osmolality
Treatment of choice for central diabetes insipidus ---------CORRECT
ANSWER-----------------vasopressin, unlimited water
Name at least 4 differentials for hypercalcemia ---------CORRECT
ANSWER-----------------1 excesss vit D