,Test Bank
po p o Rubin's p o Pathology: Clinicopathologic Foundations of
p o p o p o p o Medicine p o 7th p o
Edition
p o
Table of Contents:
p o p o
Chapter 1: Cell Adaptation, Injury and Death
po p o p o p o po p o
Chapter 2: Inflammation
p o p o
Chapter 3: Repair, Regeneration and Fibrosis
po p o p o p o p o
Chapter 4: Immunopathology
p o p o
Chapter 5: Neoplasia
p o p o
Chapter 6: Developmental and Genetic Diseases
po p o p o p o p o
Chapter 7: Hemodynamic Disorders
p o p o p o
Chapter 8: Environmental and Nutritional Pathology
po p o p o p o p o
Chapter 9: Infectious and Parasitic Diseases
po p o p o p o p o
Section II: Pathogenesis of Systemic Conditions Expandable section
p o p o p o p o p o p o p o
Chapter 10: Agingp o p o
Chapter 11: Systemic Autoimmune Diseases
po p o p o p o
Chapter 12: Sepsis
p o p o
Chapter 13: Obesity and Diabetes Mellitus
p o p o po p o p o
Chapter 14: The Pathology of Pregnancy
p o p o p o po p o
Chapter 15: The Amyloidoses
p o p o p o
Section III: Diseases of Individual Organ SystemsExpandable section
po p o p o p o p o p o p o
Chapter 16: Blood Vessels
p o p o p o
Chapter 17: The Heart
po p o p o
Chapter 18: The Respiratory System
po p o p o po
Chapter 19: The Gastrointestinal Tract
po p o p o p o
Chapter 20: The Liver and Biliary System
p o p o p o p o p o po
Chapter 21: The Pancreas
p o p o p o
Chapter 22: The Kidney
p o p o p o
Chapter 23: The Lower Urinary Tract and Male Reproductive System
po p o p o p o po p o p o p o p o
Chapter 24: The Female Reproductive System and Peritoneum
po p o p o p o p o p o p o
Chapter 25: The Breast
p o p o p o
Chapter 26: Hematopathology
p o p o
Chapter 27: The Endocrine System
p o p o p o p o
Chapter 28: The Skin
po p o p o
Chapter 29: The Head and Neck
p o p o p o p o p o
Chapter 30: Bones, Joints and Soft Tissue
po p o p o p o p o p o
Chapter 31: Skeletal Muscle and Peripheral Nervous System
po p o p o p o p o p o p o
Chapter 32: The Central Nervous System
po p o po p o p o
Chapter 33: The Eye
p o p o p o
Chapter 34: Forensic Pathology
po p o p o
,Rubin's Pathology: Clinicopathologic Foundations of Medicine
po po po po po
Chapter 1: Cell Adaptation, Injury and Death
po p o p o p o p o p o p o
Ischemia and other toxic injuries increase the accumulation of intracellular
po po po po p o po po po po
1. pocalcium as a result of: po po po p o
A) release of stored calcium from the mitochondria.
p o po po p o po p o
B) improved intracellular volume regulation. po po po
C) decreased influx across the cell membrane. p o p o po po po
D) attraction of calcium to fatty infiltrates.
p o p o p o po po
The patient is found to have liver disease, resulting in the removal of a
p o p o p o p o p o p o p o p o p o p o p o p o p o
2. lobe of his liver. Adaptation to the reduced size of the liver leads to
p o p o p o po p o p o p o p o p o p o p o p o p o p o
_ of the remaining liver cells.
p o p o po po po po
A) metaplasia
B) organ atrophy po
C) compensatory hyperplasia po
D) physiologic hypertrophy po
A person eating peanuts starts choking and collapses. His airway
p o p o p o p o p o p o p o p o p o
obstruction is partially cleared, but he remains hypoxic until he
p o p o po p o p o p o p o p o p o p o
3. reaches the hospital. The prolonged cell hypoxia caused a cerebral
p o p o p o p o po p o p o p o p o p o
infarction and resulting
p o p o _ in the p o po po
brain.
po
A) caspase activation po
B) coagulation necrosis po
C) rapid phagocytosis po
D) protein p53 deficiency po p o
Bacteria and viruses cause cell damage by
p o , which is unique
p o p o p o p o p o po po po
4. from the intracellular damage caused by other injurious agents.
po po po p o p o p o p o p o p o
A) disrupting the sodium/potassium ATPase pumppo p o p o po
B) interrupting oxidative metabolism processes p o po po
C) replicating and producing continued po po po p o injury
D) decreasing protein synthesis and function po po p o po
The patient has a prolonged interruption in arterial blood flow to his left kidney,
po p o po po p o p o po po p o po po p o po
5. pocausing hypoxic cell injury and the release of free radicals. Free radicals
po p o p o p o p o p o p o p o p o p o p o
damage cells by:
p o p o p o
A) destroying phospholipids in the cell membrane. po p o po po po
, B) altering the immune response of the cell.
po p o po p o po po
C) disrupting calcium storage in the cell.
po po p o po po
D) inactivation of enzymes and mitochondria. p o po p o po
6. Injured cells have impaired flow of substances through the cell membrane as a
po p o p o p o p o po p o po po po p o po
result of:
po p o
A) increased fat load. po po
B) altered permeability.
po
C) altered glucose utilization.
po po
D) increased surface receptors.
po po
7. Reversible adaptive intracellular responses are initiated by:
po p o po p o po p o
A) stimulus overload. p o
B) genetic mutations.
po
C) chemical messengers. po
D) mitochondrial DNA. po
8. Injured cells become very swollen as a result
po p o p o po p o p o po p o of:
A) increased cell protein synthesis.
p o po po
B) altered cell volume regulation.
po p o po
C) passive entry of potassium
p o po po p o into the cell. po po
D) bleb formation in the plasma membrane.
p o p o p o po po
A diabetic patient has impaired sensation, circulation, and oxygenation of his
po po po po po po po po po po
feet. He steps on a piece of glass, the wound does not heal, and the
po po po p o p o p o p o p o p o p o p o p o p o p o p o
9. area tissue becomes necrotic. The necrotic cell death is characterized by:
p o p o p o po p o p o p o p o p o p o p o
A) rapid apoptosis.
po
B) cellular rupture. po
C) shrinkage and collapse. po po
D) chronic inflammation.
po
A 99-year-old woman has experienced the decline of cell function associated with
po po po po po po po po po po po
10. age. A group of theories of cellular aging focus on programmed:
po po po p o p o p o p o p o p o p o p o
A) changes with genetic influences.
p o po po
B) elimination of cell receptor sites. p o po po po
C) insufficient telomerase enzyme. po po
D) DNA mutation or faulty repair.
po p o p o po
po p o Rubin's p o Pathology: Clinicopathologic Foundations of
p o p o p o p o Medicine p o 7th p o
Edition
p o
Table of Contents:
p o p o
Chapter 1: Cell Adaptation, Injury and Death
po p o p o p o po p o
Chapter 2: Inflammation
p o p o
Chapter 3: Repair, Regeneration and Fibrosis
po p o p o p o p o
Chapter 4: Immunopathology
p o p o
Chapter 5: Neoplasia
p o p o
Chapter 6: Developmental and Genetic Diseases
po p o p o p o p o
Chapter 7: Hemodynamic Disorders
p o p o p o
Chapter 8: Environmental and Nutritional Pathology
po p o p o p o p o
Chapter 9: Infectious and Parasitic Diseases
po p o p o p o p o
Section II: Pathogenesis of Systemic Conditions Expandable section
p o p o p o p o p o p o p o
Chapter 10: Agingp o p o
Chapter 11: Systemic Autoimmune Diseases
po p o p o p o
Chapter 12: Sepsis
p o p o
Chapter 13: Obesity and Diabetes Mellitus
p o p o po p o p o
Chapter 14: The Pathology of Pregnancy
p o p o p o po p o
Chapter 15: The Amyloidoses
p o p o p o
Section III: Diseases of Individual Organ SystemsExpandable section
po p o p o p o p o p o p o
Chapter 16: Blood Vessels
p o p o p o
Chapter 17: The Heart
po p o p o
Chapter 18: The Respiratory System
po p o p o po
Chapter 19: The Gastrointestinal Tract
po p o p o p o
Chapter 20: The Liver and Biliary System
p o p o p o p o p o po
Chapter 21: The Pancreas
p o p o p o
Chapter 22: The Kidney
p o p o p o
Chapter 23: The Lower Urinary Tract and Male Reproductive System
po p o p o p o po p o p o p o p o
Chapter 24: The Female Reproductive System and Peritoneum
po p o p o p o p o p o p o
Chapter 25: The Breast
p o p o p o
Chapter 26: Hematopathology
p o p o
Chapter 27: The Endocrine System
p o p o p o p o
Chapter 28: The Skin
po p o p o
Chapter 29: The Head and Neck
p o p o p o p o p o
Chapter 30: Bones, Joints and Soft Tissue
po p o p o p o p o p o
Chapter 31: Skeletal Muscle and Peripheral Nervous System
po p o p o p o p o p o p o
Chapter 32: The Central Nervous System
po p o po p o p o
Chapter 33: The Eye
p o p o p o
Chapter 34: Forensic Pathology
po p o p o
,Rubin's Pathology: Clinicopathologic Foundations of Medicine
po po po po po
Chapter 1: Cell Adaptation, Injury and Death
po p o p o p o p o p o p o
Ischemia and other toxic injuries increase the accumulation of intracellular
po po po po p o po po po po
1. pocalcium as a result of: po po po p o
A) release of stored calcium from the mitochondria.
p o po po p o po p o
B) improved intracellular volume regulation. po po po
C) decreased influx across the cell membrane. p o p o po po po
D) attraction of calcium to fatty infiltrates.
p o p o p o po po
The patient is found to have liver disease, resulting in the removal of a
p o p o p o p o p o p o p o p o p o p o p o p o p o
2. lobe of his liver. Adaptation to the reduced size of the liver leads to
p o p o p o po p o p o p o p o p o p o p o p o p o p o
_ of the remaining liver cells.
p o p o po po po po
A) metaplasia
B) organ atrophy po
C) compensatory hyperplasia po
D) physiologic hypertrophy po
A person eating peanuts starts choking and collapses. His airway
p o p o p o p o p o p o p o p o p o
obstruction is partially cleared, but he remains hypoxic until he
p o p o po p o p o p o p o p o p o p o
3. reaches the hospital. The prolonged cell hypoxia caused a cerebral
p o p o p o p o po p o p o p o p o p o
infarction and resulting
p o p o _ in the p o po po
brain.
po
A) caspase activation po
B) coagulation necrosis po
C) rapid phagocytosis po
D) protein p53 deficiency po p o
Bacteria and viruses cause cell damage by
p o , which is unique
p o p o p o p o p o po po po
4. from the intracellular damage caused by other injurious agents.
po po po p o p o p o p o p o p o
A) disrupting the sodium/potassium ATPase pumppo p o p o po
B) interrupting oxidative metabolism processes p o po po
C) replicating and producing continued po po po p o injury
D) decreasing protein synthesis and function po po p o po
The patient has a prolonged interruption in arterial blood flow to his left kidney,
po p o po po p o p o po po p o po po p o po
5. pocausing hypoxic cell injury and the release of free radicals. Free radicals
po p o p o p o p o p o p o p o p o p o p o
damage cells by:
p o p o p o
A) destroying phospholipids in the cell membrane. po p o po po po
, B) altering the immune response of the cell.
po p o po p o po po
C) disrupting calcium storage in the cell.
po po p o po po
D) inactivation of enzymes and mitochondria. p o po p o po
6. Injured cells have impaired flow of substances through the cell membrane as a
po p o p o p o p o po p o po po po p o po
result of:
po p o
A) increased fat load. po po
B) altered permeability.
po
C) altered glucose utilization.
po po
D) increased surface receptors.
po po
7. Reversible adaptive intracellular responses are initiated by:
po p o po p o po p o
A) stimulus overload. p o
B) genetic mutations.
po
C) chemical messengers. po
D) mitochondrial DNA. po
8. Injured cells become very swollen as a result
po p o p o po p o p o po p o of:
A) increased cell protein synthesis.
p o po po
B) altered cell volume regulation.
po p o po
C) passive entry of potassium
p o po po p o into the cell. po po
D) bleb formation in the plasma membrane.
p o p o p o po po
A diabetic patient has impaired sensation, circulation, and oxygenation of his
po po po po po po po po po po
feet. He steps on a piece of glass, the wound does not heal, and the
po po po p o p o p o p o p o p o p o p o p o p o p o p o
9. area tissue becomes necrotic. The necrotic cell death is characterized by:
p o p o p o po p o p o p o p o p o p o p o
A) rapid apoptosis.
po
B) cellular rupture. po
C) shrinkage and collapse. po po
D) chronic inflammation.
po
A 99-year-old woman has experienced the decline of cell function associated with
po po po po po po po po po po po
10. age. A group of theories of cellular aging focus on programmed:
po po po p o p o p o p o p o p o p o p o
A) changes with genetic influences.
p o po po
B) elimination of cell receptor sites. p o po po po
C) insufficient telomerase enzyme. po po
D) DNA mutation or faulty repair.
po p o p o po
