applied pathophysiology a conceptual
approach to the mechanisms of
disease test bank
4th edition braun ||all chapters covered 1-
18(with answer key)
,table of contents
chapter 1introduction to pathophysiology ..........................................3
chapter 2 altered cells and tissues .................................................... 10
chapter 3 inflammation and tissue repair ......................................... 17
chapter 4 altered immunity .............................................................. 25
chapter 5 infection ........................................................................... 32
chapter 6 genetic and developmental disorders ................................ 39
chapter 7 altered cellular proliferation and differentiation ............... 46
chapter 8 altered fluid, electrolyte, and acid-base balance ............... 51
chapter 9 altered neuronal transmission .......................................... 66
chapter 10 altered sensory function and pain perception .................. 73
chapter 11 altered hormonal and metabolic regulation .................... 80
chapter 12 altered reproductive function .......................................... 88
chapter 13 altered ventilation and diffusion ................................... 102
chapter 14 altered perfusion ............................................................ 51
chapter 15 altered nutrition ........................................................... 110
chapter 16 altered elimination ....................................................... 117
chapter 17 degenerative changes in aging ...................................... 124
chapter 18 integrated pathophysiologic concepts: diabetes mellitus
...................................................................................................... 135
,applied pathophysiology a conceptual approach to the mechanisms of
disease 4th edition braun
chapter 1introduction to pathophysiology
1. the nucleus , which is essential for function and survival of
the cell.
a) is the site of protein synthesis
b) contains the genetic code
c) transforms cellular energy
d) initiates aerobic metabolism
2. although energy is not made in mitochondria, they are known as
the power plants of the cell because they:
a) contain rna for protein synthesis.
b) utilize glycolysis for oxidative energy.
c) extract energy from organic compounds.
d) store calcium bonds for muscle contractions.
3. although the basic structure of the cell plasma membrane is
formed by a lipid bilayer, most of the specific membrane functions are
carried out by:
a) bound and transmembrane proteins.
b) complex, long carbohydrate chains.
c) surface antigens and hormone receptors.
d) a gating system of selective ion channels.
4. to effectively relay signals, cell-to-cell communication utilizes
chemical messenger systems that:
,a) displace surface receptor proteins.
b) accumulate within cell gap junctions.
c) bind to contractile microfilaments.
d) release secretions into extracellular fluid.
5. aerobic metabolism, also known as oxidative metabolism,
provides energy by:
a) removing the phosphate bonds from atp.
b) combining hydrogen and oxygen to form water.
c) activating pyruvate stored in the cytoplasm.
d) breaking down glucose to form lactic acid.
6. exocytosis, the reverse of endocytosis, is important in into the
extracellular fluid.
a) engulfing and ingesting fluid and proteins for transport
b) killing, degrading, and dissolving harmful microorganisms
c) removing cellular debris and releasing synthesized substances
d) destruction of particles by lysosomal enzymes for secretion
7. the process responsible for generating and conducting
membrane potentials is:
a) diffusion of current-carrying ions.
b) millivoltage of electrical potential.
c) polarization of charged particles.
d) ion channel neurotransmission.
,8. epithelial tissues are classified according to the shape of the cells
and the number of layers. which of the following is a correctly
matched description and type of epithelial tissue?
a) simple epithelium: cells in contact with intercellular matrix;
some do not extend to surface
b) stratified epithelium: single layer of cells; all cells rest on
basement membrane
c) glandular epithelium: arise from surface epithelia and
underlying connective tissue
d) pseudostratified epithelium: multiple layers of cells; deepest
layer rests on basement membrane
9. connective tissue contains fibroblasts that are responsible for:
a) providing a fibrous framework for capillaries.
b) synthesis of collagen, elastin, and reticular fibers.
c) forming tendons and the fascia that covers muscles.
d) filling spaces between tissues to keep organs in place.
10. although all muscle tissue cells have some similarities, smooth
muscle (also known as involuntary muscle) differs by:
a) having dense bodies attached to actin filaments.
b) containing sarcomeres between z lines and m bands.
c) having rapid contractions and abundant cross-striations.
d) contracting in response to increased intracellular calcium.
11. which of the following aspects of the function of the nucleus is
performed by ribosomal rna (rrna)?
,a) copying and carrying dna instructions for protein synthesis
b) carrying amino acids to the site of protein synthesis
c) providing the site where protein synthesis occurs
d) regulating and controlling protein synthesis
12. breakdown and removal of foreign substances and worn-out cell
parts are performed by which of the following organelles?
a) lysosomes
b) golgi apparatus
c) ribosomes
d) endoplasmic reticulum (er)
13. impairment in the function of peroxisomes would result in:
a) inadequate sites for protein synthesis.
b) an inability to transport cellular products across the cell
membrane.
c) insufficient energy production within a cell.
d) accumulation of free radicals in the cytoplasm.
14. after several months of trying to conceive, a couple is
undergoing fertility testing. semen analysis indicates that the mans
sperm have decreased motility, a finding that is thought to underlie
the couples inability to become pregnant.
which of the following cellular components may be defective within
the mans sperm?
a) ribosomes
b) microtubules
, c) mitochondria
d) microfilaments
15. which of the following statements is true of glycolysis?
a) glycolysis requires oxygen.
b) glycolysis occurs in cells without mitochondria.
c) glycolysis provides the majority of the bodys energy needs.
d) glycolysis produces energy, water, and carbon dioxide.
16. which of the following membrane transport mechanisms
requires the greatest amount of energy?
a) facilitated diffusion
b) passive transport
c) vesicular transport
d) simple diffusion
17. a male patient with a diagnosis of type 1 diabetes mellitus is
experiencing hyperglycemia because he lacks sufficient insulin to
increase the availability of glucose transporters in his cell membranes.
consequently, his cells lack intracellular glucose and it accumulates in
his blood. which of the following processes would best allow glucose
to cross his cell membranes?
a) facilitated diffusion
b) simple diffusion
c) secondary active transport
d) endocytosis
approach to the mechanisms of
disease test bank
4th edition braun ||all chapters covered 1-
18(with answer key)
,table of contents
chapter 1introduction to pathophysiology ..........................................3
chapter 2 altered cells and tissues .................................................... 10
chapter 3 inflammation and tissue repair ......................................... 17
chapter 4 altered immunity .............................................................. 25
chapter 5 infection ........................................................................... 32
chapter 6 genetic and developmental disorders ................................ 39
chapter 7 altered cellular proliferation and differentiation ............... 46
chapter 8 altered fluid, electrolyte, and acid-base balance ............... 51
chapter 9 altered neuronal transmission .......................................... 66
chapter 10 altered sensory function and pain perception .................. 73
chapter 11 altered hormonal and metabolic regulation .................... 80
chapter 12 altered reproductive function .......................................... 88
chapter 13 altered ventilation and diffusion ................................... 102
chapter 14 altered perfusion ............................................................ 51
chapter 15 altered nutrition ........................................................... 110
chapter 16 altered elimination ....................................................... 117
chapter 17 degenerative changes in aging ...................................... 124
chapter 18 integrated pathophysiologic concepts: diabetes mellitus
...................................................................................................... 135
,applied pathophysiology a conceptual approach to the mechanisms of
disease 4th edition braun
chapter 1introduction to pathophysiology
1. the nucleus , which is essential for function and survival of
the cell.
a) is the site of protein synthesis
b) contains the genetic code
c) transforms cellular energy
d) initiates aerobic metabolism
2. although energy is not made in mitochondria, they are known as
the power plants of the cell because they:
a) contain rna for protein synthesis.
b) utilize glycolysis for oxidative energy.
c) extract energy from organic compounds.
d) store calcium bonds for muscle contractions.
3. although the basic structure of the cell plasma membrane is
formed by a lipid bilayer, most of the specific membrane functions are
carried out by:
a) bound and transmembrane proteins.
b) complex, long carbohydrate chains.
c) surface antigens and hormone receptors.
d) a gating system of selective ion channels.
4. to effectively relay signals, cell-to-cell communication utilizes
chemical messenger systems that:
,a) displace surface receptor proteins.
b) accumulate within cell gap junctions.
c) bind to contractile microfilaments.
d) release secretions into extracellular fluid.
5. aerobic metabolism, also known as oxidative metabolism,
provides energy by:
a) removing the phosphate bonds from atp.
b) combining hydrogen and oxygen to form water.
c) activating pyruvate stored in the cytoplasm.
d) breaking down glucose to form lactic acid.
6. exocytosis, the reverse of endocytosis, is important in into the
extracellular fluid.
a) engulfing and ingesting fluid and proteins for transport
b) killing, degrading, and dissolving harmful microorganisms
c) removing cellular debris and releasing synthesized substances
d) destruction of particles by lysosomal enzymes for secretion
7. the process responsible for generating and conducting
membrane potentials is:
a) diffusion of current-carrying ions.
b) millivoltage of electrical potential.
c) polarization of charged particles.
d) ion channel neurotransmission.
,8. epithelial tissues are classified according to the shape of the cells
and the number of layers. which of the following is a correctly
matched description and type of epithelial tissue?
a) simple epithelium: cells in contact with intercellular matrix;
some do not extend to surface
b) stratified epithelium: single layer of cells; all cells rest on
basement membrane
c) glandular epithelium: arise from surface epithelia and
underlying connective tissue
d) pseudostratified epithelium: multiple layers of cells; deepest
layer rests on basement membrane
9. connective tissue contains fibroblasts that are responsible for:
a) providing a fibrous framework for capillaries.
b) synthesis of collagen, elastin, and reticular fibers.
c) forming tendons and the fascia that covers muscles.
d) filling spaces between tissues to keep organs in place.
10. although all muscle tissue cells have some similarities, smooth
muscle (also known as involuntary muscle) differs by:
a) having dense bodies attached to actin filaments.
b) containing sarcomeres between z lines and m bands.
c) having rapid contractions and abundant cross-striations.
d) contracting in response to increased intracellular calcium.
11. which of the following aspects of the function of the nucleus is
performed by ribosomal rna (rrna)?
,a) copying and carrying dna instructions for protein synthesis
b) carrying amino acids to the site of protein synthesis
c) providing the site where protein synthesis occurs
d) regulating and controlling protein synthesis
12. breakdown and removal of foreign substances and worn-out cell
parts are performed by which of the following organelles?
a) lysosomes
b) golgi apparatus
c) ribosomes
d) endoplasmic reticulum (er)
13. impairment in the function of peroxisomes would result in:
a) inadequate sites for protein synthesis.
b) an inability to transport cellular products across the cell
membrane.
c) insufficient energy production within a cell.
d) accumulation of free radicals in the cytoplasm.
14. after several months of trying to conceive, a couple is
undergoing fertility testing. semen analysis indicates that the mans
sperm have decreased motility, a finding that is thought to underlie
the couples inability to become pregnant.
which of the following cellular components may be defective within
the mans sperm?
a) ribosomes
b) microtubules
, c) mitochondria
d) microfilaments
15. which of the following statements is true of glycolysis?
a) glycolysis requires oxygen.
b) glycolysis occurs in cells without mitochondria.
c) glycolysis provides the majority of the bodys energy needs.
d) glycolysis produces energy, water, and carbon dioxide.
16. which of the following membrane transport mechanisms
requires the greatest amount of energy?
a) facilitated diffusion
b) passive transport
c) vesicular transport
d) simple diffusion
17. a male patient with a diagnosis of type 1 diabetes mellitus is
experiencing hyperglycemia because he lacks sufficient insulin to
increase the availability of glucose transporters in his cell membranes.
consequently, his cells lack intracellular glucose and it accumulates in
his blood. which of the following processes would best allow glucose
to cross his cell membranes?
a) facilitated diffusion
b) simple diffusion
c) secondary active transport
d) endocytosis
