Test Bank Verified Practice For: NUR 552 – Advanced
Pharmacotherapeutics for Advanced Practice Nurse Prescribers Exam
Questions with A+ Answers | Final Exam Guide FOR 2025/2026 (the
most recent quizzes)
Nurse Practitioner Prescriptive Authority - Regulated by State Boards of Nursing or
Pharmacy.
Benefits of APRN Prescribers - Extensive pharmacology knowledge, holistic care, less likely
to prescribe narcotics.
Clinical Judgment in Prescribing - Considers patient cost, prescribes newest meds, avoids
narcotics, and uses generics.
Criteria for Choosing Effective Drug - Based on patient input, disease guidelines, samples,
and DEA guidelines.
Nurse Practitioner Practice under Health-Care Reform - NPs control costs, practice
independently, and may shift Medicaid accountability.
Nutritional Intake Impact on Prescribing - Hypoalbuminemia affects drug distribution and
free drug availability.
Drugs with First-Pass Effect - Metabolized rapidly by the liver and may have limited desired
action.
Route of Excretion for Volatile Drugs - Likely through lungs for volatile drugs.
Storage Reservoirs for Intramuscular Drugs - Create drug reservoirs for sustained effect.
Loading Dose Purpose - Rapidly achieves therapeutic drug levels.
Therapeutic Effect Indicator on Drug Concentration Curve - Peak of action on the
concentration curve.
Phenytoin Trough Level Importance - Determines if drug is in therapeutic range.
Peak Drug Level Interpretation - Above toxic concentration may lead to adverse effects.
Receptor Agonist Property - Demonstrates reversible binding to drug receptor sites.
Receptor Antagonist Effects - May cause partial blockade of agonist drug effects.
, Factors Affecting Gastric Drug Absorption - Include liver enzyme activity and drug
properties.
IV Drug Administration - Drugs begin immediate distribution in the body.
Synergistic Drug Effects - Combined effects greater than individual drug effects.
Bioavailability Importance - Critical for drugs with narrow therapeutic ranges.
Distribution Barriers - Blood-brain barrier slows drug entry into brain cells.
Drug Metabolism Purpose - To make drugs more ionized and polar for excretion.
Metabolites Activity - May be more or less active than parent drugs.
Renal Excretion Enhancement Factors - Include reduced kidney perfusion and competition
for transport sites.
Steady State Definition - When drug intake equals elimination.
Nonvolatile - Drug not easily vaporized
Steady state - When drug absorption equals excretion
Drug-drug interaction - Effect when two medications are taken together
Oxidative-reductive processes - Metabolic processes needing specific nutrients
Half-life - Time for drug concentration to decrease by 50%
Agonist - Activates receptor for a response
Drug antagonism - Decreased physiological response when combined with another drug
Enteric-coated tablets - Oral tablets with a coating for intestinal absorption
Sustained-release capsule - Capsule releasing drug gradually over time
Drug absorption - Process of drug entering the bloodstream
Sublingual medication - Medication absorbed under the tongue
CYP 3A4 isoenzymes - Enzymes involved in drug metabolism
Therapeutic drug levels - Concentration when drug reaches steady state
Upregulation - Increased response to a drug
Pharmacotherapeutics for Advanced Practice Nurse Prescribers Exam
Questions with A+ Answers | Final Exam Guide FOR 2025/2026 (the
most recent quizzes)
Nurse Practitioner Prescriptive Authority - Regulated by State Boards of Nursing or
Pharmacy.
Benefits of APRN Prescribers - Extensive pharmacology knowledge, holistic care, less likely
to prescribe narcotics.
Clinical Judgment in Prescribing - Considers patient cost, prescribes newest meds, avoids
narcotics, and uses generics.
Criteria for Choosing Effective Drug - Based on patient input, disease guidelines, samples,
and DEA guidelines.
Nurse Practitioner Practice under Health-Care Reform - NPs control costs, practice
independently, and may shift Medicaid accountability.
Nutritional Intake Impact on Prescribing - Hypoalbuminemia affects drug distribution and
free drug availability.
Drugs with First-Pass Effect - Metabolized rapidly by the liver and may have limited desired
action.
Route of Excretion for Volatile Drugs - Likely through lungs for volatile drugs.
Storage Reservoirs for Intramuscular Drugs - Create drug reservoirs for sustained effect.
Loading Dose Purpose - Rapidly achieves therapeutic drug levels.
Therapeutic Effect Indicator on Drug Concentration Curve - Peak of action on the
concentration curve.
Phenytoin Trough Level Importance - Determines if drug is in therapeutic range.
Peak Drug Level Interpretation - Above toxic concentration may lead to adverse effects.
Receptor Agonist Property - Demonstrates reversible binding to drug receptor sites.
Receptor Antagonist Effects - May cause partial blockade of agonist drug effects.
, Factors Affecting Gastric Drug Absorption - Include liver enzyme activity and drug
properties.
IV Drug Administration - Drugs begin immediate distribution in the body.
Synergistic Drug Effects - Combined effects greater than individual drug effects.
Bioavailability Importance - Critical for drugs with narrow therapeutic ranges.
Distribution Barriers - Blood-brain barrier slows drug entry into brain cells.
Drug Metabolism Purpose - To make drugs more ionized and polar for excretion.
Metabolites Activity - May be more or less active than parent drugs.
Renal Excretion Enhancement Factors - Include reduced kidney perfusion and competition
for transport sites.
Steady State Definition - When drug intake equals elimination.
Nonvolatile - Drug not easily vaporized
Steady state - When drug absorption equals excretion
Drug-drug interaction - Effect when two medications are taken together
Oxidative-reductive processes - Metabolic processes needing specific nutrients
Half-life - Time for drug concentration to decrease by 50%
Agonist - Activates receptor for a response
Drug antagonism - Decreased physiological response when combined with another drug
Enteric-coated tablets - Oral tablets with a coating for intestinal absorption
Sustained-release capsule - Capsule releasing drug gradually over time
Drug absorption - Process of drug entering the bloodstream
Sublingual medication - Medication absorbed under the tongue
CYP 3A4 isoenzymes - Enzymes involved in drug metabolism
Therapeutic drug levels - Concentration when drug reaches steady state
Upregulation - Increased response to a drug
