Test Bank Verified Practice For: NUR 552 – Advanced
Pharmacotherapeutics for Advanced Practice Nurse Prescribers Exam
Questions with A+ Answers | Final Exam Guide FOR 2025/2026 (the
most recent quizzes)
Nurse practitioner prescriptive authority is regulated by who? - The State Board of Nursing
for Each State
What is the benefits of having an APRN prescriber? - APRN's care for patients more
holistically and include patients in making decisions regarding their care
What does clinical judgement in prescribing include? - Factoring in the cost of the particular
What is included in the criteria for choosing and effective drug for a disorder? - Consulting
nationally recognized guidelines for disease management
NP's thrive under the new health-care reform because of what? - NP's have the ability to
control care cost and improve patient outcome
Nutritional intake and lab results reflect hypoalbuminemia; why is this important for prescribers?
- The Distribution of drugs to target tissues may be affected
Drugs that have an significant first-pass effect what? - they are rapidly metabolized by the
liver and may have little if any desired action
The route of excretion of a volatile drug will likely be? - Lungs
Medroxyprogesterone (Depo Provera) is prescribed IM to create storage reservoir of the drug.
What are storage reserviors> - Increased the length of time a drug is available and active
Why is Cephalexin given every 8 hours? What knowledge of the drug does the NP know? -
Half Life
Azithromycin doing requires that the first day's doing be twice those of the other four day; This
is considered a loading does. What is a loading dose? - Rapidly actives drug levels in the
therapeutic range
The point in time on the drug concentration curve that indicates the first sign of a therapeutic
effect is the: - Onset of action
Phenytoin required that a trough level be drawn. When and why are peak and trough levels are
done - To determine if a d rug is in the therapeutic range
, Drugs that are receptor agonists may demonstrate what property? - Concentrations will
produce an adverse effect
Factors that affect gastric drug absorption include - Lipid solubility of the drug
Drugs that are receptors antagonists, such as beta-blockers, may cause what? - An
exaggerated response if abrupt discontinues
Drug administration via IV:
1) need to be lipid soluble in order to absorb easily
2) Begin distribution in the body immediately
3) Are easily absorbed if they are nonionized
4) May use pinocytosis to be absorbed - Are easily absorbed if they are nonionized
What is the combination effect when a medication is added to a regimen for a synergistic effect?
- Greater than the sum of the effects of each drug individually
Which of the following statements about bioavailability is true?
1) Bioavailability issues are especially important for drugs with narrow therapeutic
ranges or sustained-release mechanisms.
2) brands of a drug have the same bioavailability.
3) Drugs that are administered more than once a day have greater bioavailability than
drugs given once daily.
4) Combining an active drug with an inert substance does not affect bioavailability. -
Bioavailability issues are especially important for drugs with narrow therapeutic
Which of the following statements about the major distribution barriers (blood-brain or fetal-
placental) is true?
1) Water soluble and ionized drugs cross these barriers rapidly.
2) The blood-brain barrier slows the entry of many drugs into and from brain cells.
3) The fetal-placental barrier protects the fetus from drugs taken by the mother.
4) Lipid-soluble drugs do not pass these barriers and are safe for pregnant women - The
blood-brain barrier slows the entry of many drugs into and from brain cells.
Pharmacotherapeutics for Advanced Practice Nurse Prescribers Exam
Questions with A+ Answers | Final Exam Guide FOR 2025/2026 (the
most recent quizzes)
Nurse practitioner prescriptive authority is regulated by who? - The State Board of Nursing
for Each State
What is the benefits of having an APRN prescriber? - APRN's care for patients more
holistically and include patients in making decisions regarding their care
What does clinical judgement in prescribing include? - Factoring in the cost of the particular
What is included in the criteria for choosing and effective drug for a disorder? - Consulting
nationally recognized guidelines for disease management
NP's thrive under the new health-care reform because of what? - NP's have the ability to
control care cost and improve patient outcome
Nutritional intake and lab results reflect hypoalbuminemia; why is this important for prescribers?
- The Distribution of drugs to target tissues may be affected
Drugs that have an significant first-pass effect what? - they are rapidly metabolized by the
liver and may have little if any desired action
The route of excretion of a volatile drug will likely be? - Lungs
Medroxyprogesterone (Depo Provera) is prescribed IM to create storage reservoir of the drug.
What are storage reserviors> - Increased the length of time a drug is available and active
Why is Cephalexin given every 8 hours? What knowledge of the drug does the NP know? -
Half Life
Azithromycin doing requires that the first day's doing be twice those of the other four day; This
is considered a loading does. What is a loading dose? - Rapidly actives drug levels in the
therapeutic range
The point in time on the drug concentration curve that indicates the first sign of a therapeutic
effect is the: - Onset of action
Phenytoin required that a trough level be drawn. When and why are peak and trough levels are
done - To determine if a d rug is in the therapeutic range
, Drugs that are receptor agonists may demonstrate what property? - Concentrations will
produce an adverse effect
Factors that affect gastric drug absorption include - Lipid solubility of the drug
Drugs that are receptors antagonists, such as beta-blockers, may cause what? - An
exaggerated response if abrupt discontinues
Drug administration via IV:
1) need to be lipid soluble in order to absorb easily
2) Begin distribution in the body immediately
3) Are easily absorbed if they are nonionized
4) May use pinocytosis to be absorbed - Are easily absorbed if they are nonionized
What is the combination effect when a medication is added to a regimen for a synergistic effect?
- Greater than the sum of the effects of each drug individually
Which of the following statements about bioavailability is true?
1) Bioavailability issues are especially important for drugs with narrow therapeutic
ranges or sustained-release mechanisms.
2) brands of a drug have the same bioavailability.
3) Drugs that are administered more than once a day have greater bioavailability than
drugs given once daily.
4) Combining an active drug with an inert substance does not affect bioavailability. -
Bioavailability issues are especially important for drugs with narrow therapeutic
Which of the following statements about the major distribution barriers (blood-brain or fetal-
placental) is true?
1) Water soluble and ionized drugs cross these barriers rapidly.
2) The blood-brain barrier slows the entry of many drugs into and from brain cells.
3) The fetal-placental barrier protects the fetus from drugs taken by the mother.
4) Lipid-soluble drugs do not pass these barriers and are safe for pregnant women - The
blood-brain barrier slows the entry of many drugs into and from brain cells.
