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,Psychopharmacology Drugs the Brain And Behavior3rd Edition Meyer Nursing
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TestBank
toaccompany
Psychopharmacology,ThirdEdition
Meyer•Quenzer
Chapter1:PrinciplesofPharmacology
MultipleChoice
1. refer(s) to specific molecular changes that occur when a drug binds to
aparticulartargetsiteor receptor,while
aretheresultingwidespreadalterationsinfunction.
a. Drugaction;therapeuticeffects
b. Sideeffects;drugeffects
c. Therapeuticeffects; sideeffects
d. Drugaction; drugeffects
Answer:d
TextbookReference:Pharmacology:TheScience ofDrugAction
2. Afterdrugadministrationhasoccurred, theamount ofdruginthebloodthatisfreetobindat
specifictarget sites isreferred toas
a. thetherapeuticdose.
b. first-passeffects.
c. bioavailability.
d. ED50.
Answer:c
TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
3. Thespecificmolecularchangesthat occurwhena drugbinds toaparticulartarget
siteorreceptor arereferred to as
a. drugeffects.
b. drugaction.
c. sideeffects.
d. placeboeffects.
Answer:b
TextbookReference:Pharmacology: TheScienceofDrugAction
4. Whichofthefollowingisnot apossibleexplanation forplaceboeffects?
a. Pavlovianconditioning
b. Geneticvariation
c. Drugcompetition
d. Expectationofoutcome
Answer:c
TextbookReference:Pharmacology: TheScienceofDrugAction
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,Psychopharmacology Drugs the Brain And Behavior3rd Edition Meyer Nursing
Test Bank
5. The administrationofoxytocinhasbeenproposedas a treatmentforautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer:c
TextbookReference:PharmacokineticFactors DeterminingDrugAction
6. Whichfactordoesnotaffectthepharmacokineticsofadrug?
a. Routeofadministration
b. Lipidsolubility
c. Depotbinding
d. Drugaction
Answer:d
TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
7. First-passmetabolismoccurswhendrugsaretaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer:a
TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
8. Theareapostrema isone area inthebrain wherethe isnot complete.
a. cerebrospinalfluid
b. blood–brainbarrier
c. choroidplexus
d. phospholipidmembrane
Answer:b
TextbookReference:PharmacokineticFactorsDeterminingDrugAction
9. First-passmetabolism occurswithorallyadministereddrugsbecause
a. theirabsorption is slowed byfood.
b. drugsabsorbedintothe bloodstreamfromthestomachgoto theliveron
thewaytogeneralcirculation.
c. drugsmust firstsurvivetheacidic environmentof thestomach.
d. salivaryenzymesin themouth begintheprocessofmetabolism.
Answer:b
TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
10. Toxicsubstances in theblood trigger avomitingresponse byactivatingthe
a. blood–brainbarrier.
b. choroidplexus.
c. areapostrema.
d. medianeminence.
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, Psychopharmacology Drugs the Brain And Behavior3rd Edition Meyer Nursing
Test Bank
Answer:c
TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
11. Drugsadministered_ havethemost rapidonset ofaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer:d
TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
12. Ionizationofadrugdependson the ofthe solution and the
ofthedrug.
a. pH;pKa
b. pKa;pH
c. concentration;lipid solubility
d. pH;concentration
Answer:a
TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
13. Theabsorption ofadrugdependson all ofthefollowing except
a. lipidsolubility.
b. ionization.
c. bodytemperature.
d. theconcentrationofthedrug.
Answer:c
TextbookReference:PharmacokineticFactorsDeterminingDrugAction
14. Drugsthatare shouldbeavoided bywomen ofchildbearingage.
a. teratogenic
b. abletocrosstheplacental barrier
c. psychoactive
d. highlylipid-soluble
Answer:a
TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
15. Agentsthatinducedevelopmentalabnormalitiesinafetusareknown as
a. psychoactivedrugs.
b. illicitdrugs.
c. teratogens.
d. placentaldrugs.
Answer:c
TextbookReference:Pharmacokinetic FactorsDeterminingDrugAction
16. Depotbindingissaidtooccurwhendrugs
a. bindtotheirtargetsites.
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